Abstract:
A
series
of
Copper(I)
complexes with thiones of the general formula
[CuaLbScXd](H2O)e and [CuaLbSc]Xd.(H2O)e (where a = 1 - 6, b = 1 - 6, c = 0 - 6,
d = 0 - 6, e = 0 - 1 and X = Cl, Br & I) were prepared and characterized by elemental,
IR and NMR (1H and 13C) spectroscopic methods. Crystal structures of nine complexes,
[Cu(Metu)4]Cl 1, [Cu4(Dmtu)4(S)(μ-S)Cl]Cl.(H2O) 2, [Cu(DeTu)Cl]3 3, [Cu(Metu)4]Br 4,
[Cu(Dphtu)2Br]H2O 5, ([Cu(Metu)]I)6
6,
[Cu(Mtu)4]I 7, [Cu(Detu)3I] 8 and
[Cu(Dbtu)3I]0.6(H2O) 9 were determined by single crystal x-ray diffraction. An upfield
shift in the >C=S resonance of thiones in
13
C-NMR and downfield shift in the N-H
resonance in 1H-NMR were consistent with the sulfur coordination of thiones to
Copper(I). The crystal structures of 1, 4, 7, 8 and 9 show that they are monomeric having
tetrahedral or distorted tetrahedral geometries at Copper(I) center. The crystal structure of
2 showed that it consists of a tetrameric cationic complex having terminal as well as
doubly bridged Dmtu and S ligands. The complex has two kinds of coordination
environments around four Copper atoms, a distorted tetrahedral and a trigonal planer.
[Cu(Detu)Cl]3 is a trinuclear complex consisting of Cu3S3 six-membered ring possessing
chair conformation. The geometry around each Cu center was nearly trigonal planar. In 5,
the Cu(I) atom adopts a slightly distorted trigonal planar coordination. The X-ray studies
of 6 showed that the complex was hexanuclear consisting of [Metu-Cu-I] units. The
geometry around each Cu center was distorted tetrahedral. In all these complexes intra
or/and intermolecular hydrogen bonding is present in 2-D or 3-D network. The
antimicrobial activities of Copper(I) bromide complexes were evaluated by minimum
inhibitory concentrations (MIC) and they showed wide range of activity against the test
isolates.