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Downstream approaches for pure biofine chemicals and aroma substances from Cannabis sativa essential Oil

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dc.contributor.author Naz, Saima
dc.date.accessioned 2019-05-29T07:09:27Z
dc.date.accessioned 2020-04-15T02:12:04Z
dc.date.available 2020-04-15T02:12:04Z
dc.date.issued 2016
dc.identifier.govdoc 12977
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/11207
dc.description.abstract Essential oils are complex mixtures of biologically active substances used since along time as flavoring agents and constituents of number of commercial products. Currently, their importance is more highlighted due to their increasing demand for food,cosmetics and pharmaceutical industries. Recent scientific literature revealed theantimicrobial, antifungal, antioxidant and pharmacological potential of essential oils. In view of themultiple applications of essential oils, their characterization based on their chemicalprofiles, is of great importance.In the present study, indigenous specie of Cannabaceae family “Cannabis sativa” was screenedfor the isolation of essential oils. Essential oil components were fractioned, separated and isolated. The variations in the yield, chemical composition and biological activities of theessential oils and fractions were investigated in the present study with respect to temperature and technique of extraction.The hydro-distilled, steam distilled and supercritical fluid extracted essential oils were characterized fortheir physico-chemical and biological activities. It was tried to purify and separate the major constituents of Cannabis sativa essential oil by vacuum fractionation. GC-MS analysis of thechemical constituents of the isolated oils and fractions mainly revealed the presence of monoterpene hydrocarbons, sesquiterpene hydrocarbons, oxygenated monoterpenes, and oxygenated sesquiterpenes. The investigated essential oils and fractions exhibited good antioxidant, antimicrobial, cytotoxic, insecticidal, anti-inflammatory, antitumor, gastroprotective, nephroprotective, hepatoprotective activities as measured by different in- vivo and in-vitro assays and experimental models. en_US
dc.description.sponsorship Higher Education Commission, Pakistan en_US
dc.language.iso en_US en_US
dc.publisher University of Agriculture, Faisalabad. en_US
dc.subject Chemistry en_US
dc.title Downstream approaches for pure biofine chemicals and aroma substances from Cannabis sativa essential Oil en_US
dc.type Thesis en_US


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