Serum LH, FSH and Estradiol Levels in Women Using Injectable Contraceptive (Norigest) Over Long Periods of Time

Abstract

Blood glucose, serum bilirubin, serum enzymes, i.e. SAP, SGPT and SGOT, sodium and potassium, LH, FSH and estradiol level were determined in 93 women (aged 25-45). These subjects were grouped according to the time of receiving intragluteal injections (200 mg NETEN 8-weeks intervals). The groups of women receiving injections for 19-24 months showed a significant decrease (P < 0.01) in LH, FSH and estradiol levels. The pregnancy rate was 2%. Levels of LH, FSH and estradiol were elevated in women receiving injections for 25-38 months. The pregnancy rate was 3%. 17,e values were not significantly different when compared with controls. A significant increase in serum bilirubin, SAP, SGPT, SGOT, sodium and potassium levels were recorded in all treated groups. 17,e control and treated groups did not show any significant difference with respect to blood glucose levels.