Pakistan Journal of Pharmaceutical Sciences: Recent submissions

  • MECHANICAL PROPERTIES AND WATER VAPOUR PERMEABILITY OF FILM FROM HARUAN (Channa striatus) AND FUSIDIC ACID SPRAY FOR WOUND DRESSING AND WOUND HEALING 
    FEBRIYENTI, FEBRIYENTI; MOHD. NOOR, AZMIN; BIN BAI, SARINGAT (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2010-04-07)
    Aerosol is a new dosage form for wound dressing and wound healing. Concentrate of aerosols which were prepared for wound dressing and wound healing will produced films after sprayed onto the surface of wounds. The aim ...
  • GREEN TEA AMELIORATES RENAL OXIDATIVE DAMAGE INDUCED BY GENTAMICIN IN RATS 
    ABDEL-RAHEEM, IHAB T; A EL-SHERBINY, GAMAL; TAYE, ASHRAF (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2010-01-20)
    Recent studies indicate that free radicals are important mediators of renal damage induced by gentamicin (GM), an aminoglycoside antibiotic widely used in treating severe gram-negative infections. Green tea extract ...
  • DEVELOPMENT OF NEW OPHTHALMIC SUSPENSION PREDNISOLONE ACETATE 1% 
    AKRAM, MUHAMMAD; BAQIR SHYUM NAQVI, SYED; GAUHAR, SHAHNAZ (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2010-04-05)
    Formulation of a new Prednisolone acetate (1%) ophthalmic suspension to obtain a better contactibility of the drug at the site of action. The formulation was evaluated and optimized based on physiological, physicochemical ...
  • COMPARATIVE EVALUATION OF DIFFERENT EXTRACTS OF LEAVES OF PSIDIUM GUAJAVA LINN. FOR HEPATOPROTECTIVE ACTIVITY 
    K ROY, CHANCHAL; KUMAR DAS, AMIT (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2010-01-20)
    The study was designed to evaluate the hepatoprotective activity of different extracts (petroleum ether, chloroform, ethyl acetate, methanol and aqueous) of P. guajava in acute experimental liver injury induced by carbon ...
  • INTERACTION STUDY BETWEEN LEVOFLOXACIN AND OMEPRAZOLE USING URINARY PHARMACOKINETIC DATA 
    FARHANA FARUQUEE, CHOWDHURY; ULLAH, MD. ASHIK; ABUL KALAM AZAD, MOHAMMAD; RAYHAN, MD. ISRAT; PARVEEN, SEHELI; HASNAT, ABUL (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2010-04-04)
    The objective of this study was to observe the drug interaction between levofloxacin and omeprazole using urinary excretion data. Levofloxacin tablet and omeprazole capsule were administered separately as well as ...
  • IMPACT OF THE AQUEOUS EXTRACT OF ECLIPTA ALBA ON MATERNAL AGGRESSION IN RATS 
    BANJ, DAVID; JF BANJI, OTILIA; ANNAMALAI, AR; M, SHANTHMURTHY (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2010-04-03)
    Parturient females display impulsive behavior represented in the form of aggressive bouts when exposed to conspecifics. Prolonged aggression during the postpartum period could affect maternal care. Eclipta alba is traditionally ...
  • PATTERN OF ADVERSE DRUG REACTIONS DUE TO CANCER CHEMOTHERAPY IN A TERTIARY CARE TEACHING HOSPITAL IN NEPAL 
    MALLIK, S.; PALAIAN, SUBISH; OJHA, PRADIP; MISHRA, PRANAYA (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2007-07-20)
    Use of cancer chemotherapeutic drugs is associated with several adverse drug reactions (ADRs) ranging from mild nausea to fatal myelosuppression. Data regarding safety profile of cancer chemotherapy is lacking in Nepal. ...
  • DETERMINATION OF RESIDUES OF SULPHONAMIDE IN EGGS AND LAYING HENS 
    TABASSUM, SHAZIA; AHMAD, H.B.; NAWAZ, R. (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2007-07-20)
    Eggs were collected from different areas of Faisalabad city. The quantity of sulphonamides was determined in yolk, white and whole egg and compared with the permissible limit 1µg/ml for sulphadimethoxine available in ...
  • TOXIC EFFECTS OF MULTIPLE ANTICANCER DRUGS ON SKIN 
    KAMIL, NOOR; KAMIL, SABA; P. AHMED, SHAHIDA; ASHRAF, RIZWAN; KHURRAM, MOHAMMAD; OBAID ALI, MUHAMMAD (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2010-01-20)
    In this study, cutaneous toxicities associated with the administration of chemotherapy in combination are discussed. Rapidly growing cells are the targets of chemotherapy, so the skin, hair follicles, and nail matrix are ...
  • W-7 (A CALMODULIN ANTAGONIST) INHIBITS CARRAGEENAN-INDUCED PAW EDEMA IN INTACT AND ADRENALECTOMIZED RATS 
    KHAKSARI, MOHAMMAD; SHAMSIZADEH, ALI; AZARANG, AFROOZ; MAHMOODI, MEHDI (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2007-07-20)
    The aim of present study was to investigate the effect of W-7, a calmodulin antagonist, on carrageenaninduced rat’s paw edema. W-7(50 µMol/kg) was given intraperitoneally synchronous with the intraplantar injection of 0.1 ...
  • THYMOQUINONE SUPPLEMENTATION AMELIORATES ACUTE ENDOTOXEMIA-INDUCED LIVER DYSFUNCTION IN RATS 
    HELAL, GOUDA K (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2010-04-02)
    Endotoxemia caused by lipopolysaccharide (LPS) produced an inflammatory condition contributing to multiple organ failure. This study was carried out to investigate the effects of thymoquinone (TQ), the main constituent of ...
  • EFFECTIVENESS OF SILDENAFIL CITRATE (VIAGRATM) AND TADALAFIL (CIALISTM) ON SEXUAL RESPONSES IN SAUDI MEN WITH ERECTILE DYSFUNCTION IN ROUTINE CLINICAL PRACTICE 
    TABREZ ALI, SYED (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2008-07-12)
    Satisfaction with the sexual experience is considered important when evaluating the impact of treatments for erectile dysfunction, yet enhanced satisfaction has been infrequently assessed in the sexual trials. We evaluated ...
  • NEUROCHEMICAL AND BEHAVIORAL EFFECTS OF M-CPP IN A RAT MODEL OF TARDIVE DYSKINESIA 
    IKRAM, HUMA; SAMAD, NOREEN; HALEEM, DARAKHSHAN JABEEN (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2007-07-20)
    Present study was designed to monitor the responsiveness of 5HT (5-Hydroxytryptamine) -2C receptors following the long-term administration of haloperidol in rats. Effects of m-CPP (meta-Chlorophenyl piperazine) were monitored ...
  • HEPATOTOXICITY OF CARBON TETRACHLORIDE: PROTECTIVE EFFECT OF GONGRONEMA LATIFOLIUM 
    OE, ETIM; EJ, AKPAN; IF, USOH (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2008-07-11)
    The protective effect of the ethanolic extract of Gongronema latifolium (GLE) on carbon tetrachloride (CCI4) induced hepatic toxicity was studied. Liver enzymes studied included alanine aminotransferase (ALT), aspartate ...
  • BEHAVIORAL EFFECTS OF 1-(m-CHLOROPHENYL)PIPERAZINE (m-CPP) IN A RAT MODEL OF TARDIVE DYSKINESIA 
    SAMAD, NOREEN; A HALEEM, MUHAMMAD; J HALEEM, DARAKHSHAN (Karachi:Pakistan Journal of Botany, Botanical Garden, University of Karachi, 2008-07-10)
    The present study was designed to monitor the responsiveness of 5-hydroxy tryptamine (5-HT)-2C receptor in rats treated with haloperidol exhibiting tardive dyskinesia (TD). Results show that haloperidol injected at a ...
  • ANTI-INFLAMMATORY AND ANALGESIC ALKALOID FROM SIDA CORDIFOLIA LINN. 
    SUTRADHAR, RANAJIT KUMAR; RAHMAN, AKM MATIOR; AHMAD, MESBAHUDDIN; BACHAR, SITESH; SAHA, ACHINTO; ROY, TAPASHI (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2007-07-20)
    The analgesic and anti-inflammatory activities of a new alkaloid, 1,2,3,9-tetrahydro-pyrrolo [2,1-b] quinazolin 3-ylamine (compound 1) isolated from Sida cordifolia Linn. were investigated in animal models. In the acetic ...
  • PROTECTIVE EFFECT OF CAPTOPRIL AGAINST CISPLATIN-INDUCED NEPHROTOXICITY IN RATS 
    M EL-SAYED, EL-SAYED; F ABD-ELLAH, MOHAMED; M ATTIA, SABRY (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2008-07-09)
    This study has been initiated to determine whether captopril, an angiotensin-converting enzyme (ACE) inhibitor containing sulfhydryl (-SH) group can protect against cisplatin-induced nephrotoxicity in rats. A single dose ...
  • SYSTEMATIC REVIEW ON “VITAMIN E AND PREVENTION OF COLORECTAL CANCER” 
    ARAIN, MUBASHIR ASLAM; QADEER, ASMA ABDUL (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2010-04-01)
    Colorectal cancers (CRC) are highly prevalent cancer all over the world and need appropriate and timely prevention and treatment. Since years it has been argued that antioxidant vitamins have a potential role in the prevention ...
  • EVALUATION OF ANTIOXIDANT PROPERTIES OF SILYMARIN AND ITS POTENTIAL TO INHIBIT PEROXYL RADICALS IN VITRO 
    ASGHAR, ZARBAN; MASOOD, ZIAEE (Karachi:Pakistan Journal of Botany, Botanical Garden, University of Karachi, 2008-07-08)
    Silymarin (milk thistle) has been used for centuries as a natural remedy for diseases of liver and biliary tract. The present study was carried out to evaluate the in vitro free radical scavenging activity and ...
  • IN VITRO ANTIOXIDANT ACTIVITY OF ROOTS OF THESPESIA LAMPAS DALZ AND GIBS 
    SWARAN B, SANGAME; KRISHNAN BR, BALA; DESHRAJ, CHUMBHALE; B, JAYAKAR (Karachi: Faculty of Pharmacy, University of Karachi, 2009-10-04)
    The free radical scavenging potential of roots of Thespesia lampas Dalz and Gibs was studied by different antioxidant models. Free radicals are implicated for more than 80 diseases including Diabetes mellitus, arthritis, ...

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