Pakistan Journal of Pharmaceutical Sciences: Recent submissions

  • REVIEW DOES VITAMIN E HAVE A ROLE IN TREATMENT AND PREVENTION OF ANEMIA’S? 
    TANVEER JILANI; MOHAMMAD PERWAIZ IQBAL (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2011-04-23)
    Vitamin E is a highly effective fat-soluble vitamin with a variety of cellular membrane stabilizing-antioxidant and non-antioxidant functions. Vitamin E has been suggested to prevent the oxidation of polyunsaturated ...
  • SHORT COMMUNICATION INVESTIGATION OF HYPERICUM PERFORATUM EXTRACT ON CONVULSION INDUCED BY PICROTOXIN IN MICE 
    ETEMAD, LEILA; MAHMOUD REZA HEIDARI; MOHAMMAD HEIDARI; MOHAMMAD MOSHIRI; BEHRAVAN, EFFAT; ABBASIFARD, MITRA; AZIMZADEH, BEHZAD SARVAR (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2011-04-22)
    Therapeutic effect of Hypericum perforatum L. has been well known. The aim of this study is to investigate the anticonvultant effects of Hypericum methanolic extract against seizure induced by picrotoxin in mice. The ...
  • REPORT TREATMENT OF NIGELLA SATIVA IN EXPERIMENTAL SEPSIS MODEL IN RATS 
    ALICI, OZLEM; KAVAKLI, HAVVA SAHIN; KOCA, CEMILE; ALTINTAS, NERIMAN DEFNE (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2011-04-21)
    This experimental study was designed to determine effects of Nigella sativa oil (NSO) on endothelin-1 (ET-1) level and oxidative stress parameters, superoxide dismutase (SOD) and malondialdehyde (MDA) in a rat sepsis ...
  • ANTI LIPID PEROXIDATION ACTIVITY OF PIPER TRIOICUM ROXB. AND PHYSALIS MINIMA L. EXTRACTS 
    DINAKARAN, SATHIS KUMAR; SARASWATHI, NARASIMHA RAJU; RAO NALINI, VENKATA RAMA; SRISUDHARSON; BODANAPU, VENKAT RAM REDDY; HARANI AVASARALA; DAVID BANJI (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2011-07-20)
    Attempt has been made to evaluate free radical scavenging activity of ethanolic extract of Piper trioicum Roxb. and Physalis minima L. individually. In this study goat liver has been used as lipid source. This in ...
  • REPORT IN VIVO ANTIOXIDANT ACTIVITY OF ZATARIA MULTIFLORA BOISS ESSENTIAL OIL 
    FARIBA SHARIFIFAR; AMIN DERAKHSHANFAR; DEHGHAN-NUDEH, GHOLAMREZA; ABBASI, NAJMA; ABBASI, REZA; GHARAEI, REZA REZAEI; KOOHPAYEH, ABED; DANESHPAJOUH, MOHAMMAD (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2011-04-20)
    Zataria multiflora Boiss. (Lamiaceae) is an endemic plant to Iran with many traditional uses. We have reported previously in vitro antioxidant activity of the essential oil of the plant. In the present work we aimed to ...
  • SERUM ESTROGEN AND INTERLEUKIN-6 LEVELS IN POSTMENOPAUSAL FEMALE OSTEOARTHRITIS PATIENTS 
    SADIA AFZAL; AZIZA KHANAM (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2011-04-19)
    The objective of the present study is to determine whether the levels of endogenous estrogen and interleukin-6 (IL-6) are associated with osteoarthritis (OA) in postmenopausal women. Forty-three patients who were suffering ...
  • DESIGN AND EVALUATION OF A NEW FORMULATION OF ENALAPRIL MALEATE TABLET 
    REHANA BIBI; BAQIR SHYUM NAQVI; MUHAMMAD HARRIS SHOAIB; NAJIA RAHIM (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2011-04-18)
    Enalapril maleate, one of the Angiotensin converting enzyme (ACE) inhibitor is effective in the treatment of hypertension. Enalapril maleate is selected for the present study. The aim of this study was to develop a ...
  • ANTI-INFLAMMATORY AND ANALGESIC ACTIVITIES OF ETHANOLIC EXTRACT OF SPHAERANTHUS INDICUS LINN 
    ADAM ALI; NAQVI, SYED BAQIR SHYUM; SHAHNAZ GAUHAR; REHANA SAEED (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2011-07-20)
    The aim of the present study was to evaluate the intensity of the anti-inflammatory and analgesic activities of Sphaeranthus indicus on albino mice and rat of either sex. The flowers of S. indicus are an important herb ...
  • STEROID SENSITIVE NEPHROTIC SYNDROME IN PAEDIATRICS 
    SYEDA JAVARIA NADIR; NAZISH SALEEM; FATIMA AMIN; KHAWAJA TAHIR MAHMOOD (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2011-04-17)
    Nephrotic syndrome is basically a set of signs or symptoms that may point to kidney problems, a condition when large amounts of protein leak out into the urine. In children protein excretion greater than 40 mg/m2 .hr-1 ...
  • ANTIDIARRHOEAL AND ANTIULCER ACTIVITIES OF HIPPOCRATEA AFRICANA ROOT EXTRACT 
    OKOKON, JUDE EFIOM; AKPAN, HENRY DAN; UMOH, EMEM EKPO; EKAIDEM, ITEMOBONG SUNDAY (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2011-04-16)
    The effect of ethanol root extract of H. africana on experimentally induced diarrhoea and ulcer was studied in rodents. The extract (200 – 600mg/kg) considerably inhibited castor oil induced diarrhoea, small intestine transit ...
  • FORMULATION AND EVALUATION OF FICUS GLOMERATA MUCILAGE SUSTAINED RELEASE MATRIX TABLETS OF GLICLAZIDE 
    AHAD, HINDUSTAN ABDUL; KUMAR, CHITTA SURESH; BUDIDET, KISHORE KUMAR REDDY; BATTULA, SUMA PADMAJA; AYYAVALA, CHANDRA SEKHAR (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2011-07-20)
    The main aim of present investigation was to develop sustained release matrix tablets of Gliclazide using fruit mucilage from the plant Ficus glomerata. Varying ratios of drug and polymer viz. 1:0.25, 1:0.5, 1:0.75, ...
  • ANTI DIABETIC EFFECT OF ACHYRANTHES RUBROFUSCA LEAF EXTRACTS ON ALLOXAN INDUCED DIABETIC RATS 
    GEETHA, GOVINDARAJULU; GOPINATHAPILLAI, PRASANTH KALAVALARASARIEL; SANKAR, VEINDRAMUTHU (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2011-04-15)
    The aqueous and ethanolic extracts of Achyranthes rubrofuca leaves (AR) were studied for their hypoglycemic activity. Thirty animals were taken and they were divided into five groups. First group acts as control, remaining ...
  • INVESTIGATING THE IN VITRO DRUG RELEASE KINETICS FROM CONTROLLED RELEASE DICLOFENAC POTASSIUM-ETHOCEL MATRIX TABLETS AND THE INFLUENCE OF CO-EXCIPIENTS ON DRUG RELEASE PATTERNS 
    SHEFAAT ULLAH SHAH; KIFAYAT ULLAH SHAH; ASIMUR REHMAN; KHAN, GUL MAJID (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2011-04-14)
    The objective of the study was to formulate and evaluate controlled release polymeric tablets of Diclofenac Potassium for the release rate, release patterns and the mechanism involved in the release process of the drug. ...
  • EFFECT OF NATURAL HONEY ON HUMAN PLATELETS AND BLOOD COAGULATION PROTEINS 
    ASIF AHMED; KHAN, RAFEEQ ALAM; AZIM, M. KAMRAN; SAEED, S. ARSHAD; MESAIK, M. AHMED; SHAKIL AHMED; IMRAN IMRAN (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2011-07-20)
    Present study was conducted to determine the effects of honey on blood hemostasis, in-vitro effect of honey was observed on platelet aggregation and blood coagulation employing, activated partial prothrombin time (aPTT), ...
  • ANTAGONISTIC BACTERIA FROM LIVE CORALS, TUTICORIN COASTAL WATERS, SOUTHEASTERN INDIA 
    CHELLARAM, CHINNACHAMY; SREENIVASAN, SUBRAMANI; ANAND, THANKAPPAN PREM; KUMARAN, SEKARGOUNDER; KESAVAN, DHAMODARAN; PRIYA, GOVINDARAJAN (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2011-04-13)
    The objective of this study is to isolate and production of secondary metabolites with bioactive substances by coral reef (Acropora formosa and Favia palida) associated bacteria was carried out from the Tuticorin ...
  • ANTISPASMODIC ACTIVITY OF TEUCRIUM STOCKSIANUM BOISS. 
    NIAZ ALI; SYED WADOOD ALI SHAH (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2011-04-12)
    The aim of the study was to explore the traditional antispasmodic use of Teucrium stocksianum on scientific grounds, and preliminary screen the specie for phytochemical constituents. Crude methanolic extract of aerial parts ...
  • LICHENS AS POSSIBLE SOURCES OF ANTIOXIDANTS 
    KOSANIĆ, MARIJANA; RANKOVIĆ, BRANISLAV (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2011-04-11)
    Acetone, methanol and aqueous extracts of the lichen Cetraria islandica, Lecanora atra, Parmelia pertusa, Pseudoevernia furfuraceae and Umbilicaria cylindrica were investigated for antioxidant activity by five different ...
  • EFFECTS OF DEXAMETHASONE AND ATORVASTATIN ON ATRIAL SODIUM CURRENT AND ITS EARLY TACHYCARDIA-INDUCED ELECTRICAL REMODELING IN RABBITS 
    ROMAN LASZLO; MAREIKE SCHWIEBERT; MENZEL, KAREN ANNA; CHRISTIAN EICK; BIRGIT SCHREINER; JUERGEN SCHREIECK (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2011-07-20)
    ABSTRACT Purpose: Atrial fibrillation (AF) results in tachycardia-induced ionic remodeling. Pharmacological prevention of tachycardia-induced ionic remodeling not only with “classical” antiarrhythmics but also with drugs ...
  • PREPARATION, IN-VITRO AND IN-VIVO CHARACTERIZATION OF TRANSDERMAL PATCH CONTAINING GLIBENCLAMIDE AND ATENOLOL: A COMBINATIONAL APPROACH 
    ANITHA, POSINA; RAMKANTH, SUNDARAPANDIYAN; MOHAMED T S SALEEM; UMASANKARI, KOMMIREDDY; REDDY, BODDU PRAVEEN; CHETTY, MADHUSUDHANA (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2011-04-10)
    A novel aspiration in treatment of chronic disease like diabetes associated with other non communicable disease risk factors, such as hypertension is to provide greater therapeutic effect, overcome the side effects by ...
  • MODIFIED PICRATE METHOD FOR DETERMINATION OF CYANIDE IN BLOOD 
    MUHAMMAD AVAIS; KHAN, MUHAMMAD SARWAR; KHAN, MUHAMMAD ARIF; KAMRAN ASHRAF; AMAR NASIR; MASOOD RABBANI; ABU SAEED HASHMI (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2011-04-09)
    Cyanide (CNֿ) is widely distributed in the ecosystem and has been associated with toxic effects in humans and animals. Most outbreaks of CNֿ poisoning in animals result from ingestion of plants containing cyanogenic glycosides. ...

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