Pakistan Journal of Pharmaceutical Sciences: Recent submissions

  • 6-shogaol protects against diabetic nephropathy and cardiomyopathy via modulation of oxidative stress/NF-κB pathway 
    Waleed H Al Malki; Ihab T Abdel-Raheem; Mohamed Z Dawoud; Randa F Abdou (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-09-13)
    Diabetes dramatically increases the risk of numerous heart and kidney troubles. Diabetic nephropathy (DN) and cardiomyopathy (DC) are major causes of death. The pathophysiology of DN/DC includes inflammatory and oxidative ...
  • Imbalances of Pro-inflammatory cytokines in myocardial infarction patients 
    Farhan Jaleel; Allah Bux Ghanghro; Saima Aqil; Muhammad Sameer Qureshi; Tariq Ashraf (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-09-12)
    To assess levels of Interleukin-1 β and CRP, in Diabetic and Non-diabetic Myocardial Infarction patients, prior to and post angioplasty. 200 patients were recruited in the study. MI patients between the age of 40 and 60 ...
  • Chitosan coated chlorogenic acid and rutincomposite phospholipid liposomes: Preparation, characterizations, permeability and pharmacokinetic 
    Zeng, Cheng; Zheng, Ruifang; Jiang, Wen; He, Chenghui; Li, Jianguang; Xing, Jianguo (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-09-11)
    In order to research and enhance bioavailability of chlorogenic acid and rutin(CA-R) via the oral route, chitosan coated composite phospholipid liposomes (C-CPLs) were applied to study on preparation, permeability and ...
  • Prevalence of mecA: Genotyping screening of community acquiredMRSA isolates in Karachi, Pakistan 
    Tuba Siddiqui; Iyad Naeem Muhammad; Khan, Muhammad Naseem; Sakina Fatima; Nausheen Alam; Rida Masood; Rehana Saeed; Ghazala Raza Naqvi; Talat Naqvi (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-09-10)
    Among resistant nosocomial and community pathogens, MRSA has become the most serious pathogen, causing life threatening infections worldwide. In S.aureus, quick and exact recognition of methicillin (cefoxitin) resistance ...
  • Beyond conventional therapies: Complementary and alternative medicine in the management of hypertension: An evidence-based review 
    Wong, Ang Peng; Kassab, Yaman Walid; Mohamed, Abdul Latiff; Abdul Qader, Amelah Mohammed (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    Hypertension is one of the major causes of morbidity and mortality. Worldwide, Hypertension is estimated to cause 7.5 million deaths, about 12.8% of the total of all deaths. This accounts for 57 million disability adjusted ...
  • REVIEW MicroRNAs: A new paradigm towards mechanistic insight of diseases 
    Asif Nadeem; Muhammad Rizwan Ashraf; Maryam Javed; Tanveer Hussain; Muhammad Salman Tariq; Masroor Ellahi Babar (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-10-04)
    : In 1993 miRNAs were discovered during a research on Caenorhabditis elegans conducted by Victor Ambros and Gary Ruvkun. The gene lin-4 that played important role in development in C. elgans was observed not encoding any ...
  • MINI REVIEW Epigenetics: Quest for no-escape to HIV, a persistent pathogen 
    Bhatti, Muhammad Umar; Haseeb Amir Riaz; Bushra Tabassum; Nida Toufiq; Khan, Anwar; Muhammad Tariq; Iqra Yousaf; Imtiaz Ahmad Sajid; Mariam Shahid; Maryam Zameer (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-10-03)
    Acquired Immune Deficiency Syndrome (AIDS) is a disease infection mix, which is primarily because of 'deficient' immune system. Human Immune-deficiency Virus (HIV) makes the immune system susceptible to many infections ...
  • REPORT Physicochemical and Antimicrobial properties of canola (Brassica napus L.) seed oil 
    Nazima Batool; Muhammad Arshad; Fayyaz-ul-Hassan; Noshin Ilyas; Armghan Shahzad (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-10-02)
    Canola oil has been used in the Pakistan for the treatment of various diseases and skin infections. Oil was extracted with n-hexane from the seeds of canola (Brassica napus L.) and was evaluated for free fatty acid value. ...
  • Fast chromatographic screening method for 7 drugs of potential threat in drug facilitated crimes 
    Beril Anılanmert; Ibrahim Narın; Ibrahim Aydın; Munevver Acıkkol (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    In cases where pharmaceuticals and pharmaceutical candidates are involved in drug facilitated crimes (DFC), like organ theft, robbery, rape and suicides, the analysis of drug powders or solution residues found in crime ...
  • REPORT Ouabain inhibits RAW264.7 cells proliferation and induces apoptosis via Bcl-2 and bax expression 
    Luo, Yi; Qin, Hongxia; Zhao, Lin; Jin, Long; Jiang, Anan; Li, Xuewei; Li, Mingzhou; Wang, Xun (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-10-01)
    Ouabain is used in the clinical treatment of the cardiovascular diseases and it can be extensively investigated due to its promising pharmacological, pathological, and physiological properties. The present study is aimed ...
  • Regional variation in the chemical composition and antioxidant activity of Rosmarinus officinalis L. from China and the Mediterranean region 
    Bing Wang; Ling Ma; Lei Yin; Jing Chen; Yuanbin Zhang; Lin Dong; Xinhui Zhang; Xueyan Fu (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    Rosemary is an aromatic evergreen shrubby herb that is native to the Mediterranean region. This herb is now widely cultivated in many regions of the world. Rosemary is widely used in traditional Chinese medicines, foods, ...
  • REPORT Model studies of transmembrane interaction of FcεRIα/FcRγ reveal novel strategies to inhibit allergic responses 
    Asifa Majeed; Amir Rashid; Birgit Helm (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-09-30)
    The high-affinity IgE receptor complex plays an essential part in allergic responses and involved in downstream signaling, released inflammatory mediators that cause allergic responses. The transmembrane region of the ...
  • Knowledge of modes of HIV transmission among public secondary school students in urban and rural areas in Malaysia 
    Khan, Muhammad Anwar Nawab; Nurul Aida Md Rosly; Abu Bakar Abdul Majeed; Nahlah Elkudssiah Ismail (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-09-29)
    The school students are of particular importance in the HIV/AIDS awareness policies at both local and international level. This study was conducted to assess the level of knowledge of the modes of HIV transmission among ...
  • Palladium glutathione, N-acetylcysteine, D-penicillamine conjugation chemistry 
    Muhammad Mukhtiar; Syed Umer Jan; Khan, Muhammad Farid; Naseem Ullah; Abid Hussain; Saif ur Rehman; Qureshi, Muhammad Murtaza (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    The metalloelement Palladium has a number of potential Pharmaco-clinical advantages. Palladium compounds have antiviral, antibacterial, neuroprotective and antitumor properties. However studies have also indicated some ...
  • Pharmacological studies of Adhatoda vasica and Calotropis procera as resource of bio-active compounds for various diseases 
    Waseem Ahmed; Rafia Azmat; Khan, Shah Masaud; Khan, M Safeer; Abdul Qayyum; Ayaz Mehmood; Khan, Sami Ullah; Ijaz Hussain (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-09-28)
    Adhatoda vasica and Calotropis procera species were investigated as a resource for new diverse pharmacological agents including B complex, individual total phenolic compounds and antioxidants for curing and treatments of ...
  • GC-MS profile of bioactive compounds from medicinally important Periploca hydaspidis 
    Rafi Ullah; Jehan Bakht; Mohammad Shafi; Muhammad Raza Shah (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-09-27)
    The aim of the present study was to investigate bioactive compounds in different solvent extracted samples from the stem tissues of P. hydaspidis using Gas Chromatography and Mass Spectroscopy techniques. GC-mass spectrum ...
  • Preparation of levodopa/carbidopa compound drug resins 
    Hongfei Liu; Hui Ding; Dandan Zhang; Fengsi; Changshan Sun (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    The main objective of this study was to prepare the levodopa/carbidopa compound drug resins and investigate affecting factors such as drug concentration, temperature, particle size. The drug resins were made by bath method ...
  • Effect of haloperidol on behavioral sensitization and cognition in methylphenidate and buspirone-methylphenidate co-administered rats 
    Nausheen Alam; Rahila Ikram (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-09-26)
    Attenuation of methylphenidate-induced behavioral sensitization and cognitive tolerance by buspirone coadministration has been reported previously. Dopamine D2-receptors are considered to be important in methylphenidateinduced ...
  • Anti-inflammatory effect of the compounds from the flowers of Trollius chinensis 
    Liu, Li-Jia; Hu, Xiu-Hua; Guo, Li-Na; Wang, Ru-Feng; Zhao, Qi-Tao (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-09-25)
    In order to investigate the anti-inflammatory activity of flavonoids, phenolic acids, and alkaloids from the flowers of Trollius chinensis, some representative compounds, namely, orientin, 2"-O-β-L-galactopyranosylorientin, ...
  • Disposition kinetics of omeprazole in healthy female volunteers in Pakistan 
    Sadia Ashraf; Tanweer Khaliq; Ijaz Javed; Bilal Aslam; Nazia Qadir; Nadia Noor (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    Omeprazole (OMP) a proton pump inhibitor is widely used to suppress gastric acid secretions of parietal cells of stomach and metabolized predominantly by CYP2C19. The objective of the present study was to investigate the ...

Search DSpace


Advanced Search

Browse

My Account