Pakistan Journal of Pharmaceutical Sciences: Recent submissions

  • A study of serological markers and lipid profile in non-alcoholic liver cirrhosis patients 
    Khan, Sadaf; Jamal, Siddiqua (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    Cirrhosis is the end result of chronic liver damage, associated with altered serum biomarkers and lipid profile. However, only few studies regarding serum biomarkers and plasma lipid profile in non-alcoholic liver cirrhosis ...
  • Effect of the serum of rats treated with Suo Quan pill on embryonic stem cells 
    Xu, Jing- Jing; Huang, Ping; Xiang, Yun-Ya; Tan, Bo; Wu, Qing-He; Ze-Hui Qin, Hong-Ying Cao (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-01-04)
    Suo Quan pill(SQP), a well-known and classical traditional Chinese medicine compound, consists of three traditional Chinese medicine: Alpinia oxyphylla Miq., Lindera aggregata (Sims) Kosterm., Dioscorea opposite. Its ...
  • Neurite outgrowth properties of Calotropis procera: In search for a neuroprotectant 
    Aisha Kamal, Aisha Kamal; Zafar Saeed Saify, Zafar Saeed Saify; Khawar Saeed Jamali, Khawar Saeed Jamali; Priya Tufail, Priya Tufail; Aiman Kanwal, Aiman Kanwal; Khan, Faisal; Sonia Siddiqui, Sonia Siddiqui (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-01-03)
    In view of the well-documented medicinal properties of Calotropis procera (CP), the present study was designed to evaluate the neuroprotective effect of the extract. We have prepared a methanolic extract of Calotropis ...
  • Squid ink polysaccharide prevents chemotherapy induced injury in the testes of reproducing mice 
    Luo, Ping; Liu, Hua-Zhong; Yan Le, Xiao; Du, Hui; Kang, Xin-Huang (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    The present study was conducted to investigate the preventive effects of squid ink polysaccharides (SIP) on the damage of sperm and reproduction induced by cyclophosphamide that is most commonly used for treating clinically ...
  • Biosurfactants production potential of native strains of Bacillus cereus and their antimicrobial, cytotoxic and antioxidant activities 
    Madiha Basit, Madiha Basit; Muhammad Hidayat Rasool, Muhammad Hidayat Rasool; Naqvi, Syed Ali Raza; Muhammad Waseem, Muhammad Waseem; Bilal Aslam, Bilal Aslam (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-01-02)
    Present study was designed to evaluate the biosurfactant production potential by native strains of Bacillus cereus as well as determine their antimicrobial and antioxidant activities. The strains isolated from garden soil ...
  • Zein based magnesium oxide nanoparticles: Assessment of antimicrobial activity for dental implications 
    Naguib, Ghada H; Khaled M Hosny, Khaled M Hosny; Ali H. Hassan, Ali H. Hassan; Faten Al Hazmi, Faten Al Hazmi; yman Al Dharrab, yman Al Dharrab; Hala M Alkhalid, Hala M Alkhalid; Mohamed T Hamed, Mohamed T Hamed; Abeer M Alnowaiser, Abeer M Alnowaiser; Pashley, David H (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-01-01)
    MgO nanoparticles have been recently discovered as an antibacterial, however, they limited by property degradation due to agglomeration. The addition of a coating agent, such as a zein polymer, is effective in preventing ...
  • Synthesis, optimization and biological evaluation of 99mTc-digoxin as possible cardiac imaging agent 
    Bokhari, Tanveer Hussain; Roohi, Samina; Hina, Saira; Saeed, Shabana (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    Heart imaging radiopharmaceuticals could improve the diagnostic value of routine heart scanning for detecting cardiac disorders. The aim of the study was to prepare high radiochemical purity 99mTc-Digoxin in a yield of ...
  • Pharmacological validation of the folkloric uses of Cyperus rotundus L. in different ailments: An in vivo and in vitro research 
    Hussain, Musaddique; Waqas, Hafiz Muhammad; Hussain, Ikhlaq; Majeed, Abdul; Raza, Shahid Masood; Janbaz, Khalid Hussain (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    In vivo and in vitro research study was conducted on Cyperus rotundus to evaluate the sound mechanistic background in the treatment of gastrointestinal, bronchial and vascular disorders as well as in pain, emesis, pyrexia ...
  • A clinical study showing altered antioxidants profile in patients with hypertension 
    Khan, Abad; Iqbal, Zafar (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    We compared the plasma antioxidants level of normal control group with that of hypertensive patients in order to test the hypothesis “that antioxidants level has been diminished in hypertensive patients and that antioxidants ...
  • REPORT Susceptibility of avian pathogenic Escherichia coli from Zoo birds in Indonesia to antibiotics and disinfectants 
    Sajid Umar, Sajid Umar; Ana Triana Maiyah, Ana Triana Maiyah; Mehwish Shareef, Mehwish Shareef; Hajra Qadir, Hajra Qadir; Qamar-un-Nisa, Qamar-un-Nisa; Seema Abbas, Seema Abbas (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-04-02)
    Antibiotic resistance in avian pathogenic Escherichia coli (APEC) is a common problem in the Indonesian poultry industry. Zoo birds have been postulated as sentinels, reservoirs, and potential spreaders of antibiotic ...
  • Effects of Cordyceps sinensis on macrophage function in high-fat diet fed rats and its anti-proliferative effects on IMR-32 human neuroblastoma cells 
    Dos Santos, Leandro Freire; Rubel, Rosalia; Bonatto, Sandro Jose Ribeiro; Yamaguchi, Adriana Aya; Torres, Maria Fernanda; Soccol, Vanete Thomaz; Da Silva, Andre Luís Lopes; Soccol, Carlos Ricardo (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    Macrophages have been considered an elusive yet emerging therapeutic target in tumor development since they are an important component in tumor microenvironment. The purpose of the present study was to evaluate the effect ...
  • Prescribing pattern of angiotensin receptor blocker: A study of errors and drug-drug interactions 
    Nesar, Shagufta; Shoaib, Muhammad Harris; Rafiq, Kiran; Rahim, Najia; Muhammad, Iyad Naeem; Iffat, Wajiha (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    Prescriptions comprising multi-drug therapy mostly illustrate the prescribing error. The phenomenon of error is bonded with human inaccuracy. The erroneous practice is observed in under developed countries like Pakistan, ...
  • SHORT COMMUNICATION Synthesis of drug metal complexes and their influence on human platelet aggregation 
    Mansoor Ahmed, Mansoor Ahmed; Mohsin Ali, Mohsin Ali; Ayatollahi, Seyed Abdulmajid; Marjan Esfahanizadeh, Marjan Esfahanizadeh; Farzad Kobarfard, Farzad Kobarfard; Ameer Hasan, Ameer Hasan; Khan, Khalid Mohammed; Syed Moazzam Haider, Syed Moazzam Haider (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-04-01)
    During the past few decades the emergence of inorganic medicinal chemistry has been developed novel therapeutic agents. Researcher's perseverance in this branch of chemistry has led them to explore further valuable chemical ...
  • Analgesic and anti-inflammatory activities of fixed oil of Macrotyloma uniflorum (Lam.) Verdc. in mice and rats 
    Syeda Anum Fatima, Syeda Anum Fatima; Baig, Sadia Ghousia; Muhammad Mohtasheem ul Hasan, Muhammad Mohtasheem ul Hasan; Salman Ahmed, Salman Ahmed; Salma, Salma (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-03-31)
    Macrotyloma uniflorum commonly known as horse gram or kulthi bean is grown as a pulse for livestock and human consumption. The beans contain about 1.3% fat, 18% protein, 15% carbohydrate along with vitamins and minerals. ...
  • Evaluation of phytochemical and in vitro antioxidant activity of water and acetone extracts of selected vegetables 
    Faria Nisar, Faria Nisar; Mirza, Muhammad Aslam; Malik, Riffat Naseem; Ch, Muhammad Aziz; Kauser Yasmeen, Kauser Yasmeen (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-03-30)
    The aim of this study was to determine antioxidant activity of Brassica oleracea (Cabbage), Brassica rapa (Turnip) and Raphanus sativus (Radish). All of the three selected vegetables were ultrasonically extracted in water ...
  • Antifungal and cytotoxic activities of selected medicinal plants from Malaysia 
    Chan, Yik Sin; Cheah, Yit Hong; Chong, Poh Zen; Lai Khor, Hui; Siang Teh, Wen; Khoo, Kong Soo; Chooi Ong, Hean; Weng Sit, Nam (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    This study was conducted to investigate the antifungal potential and cytotoxicity of selected medicinal plants from Malaysia. The extracts from the stem of Cissus quadrangularis and the leaves of Asplenium nidus, Pereskia ...
  • Pharmacophoric screening of newly synthesized isoniazid derivatives and their antimycobacterial activity 
    Sabahat Naeem, Sabahat Naeem; Shamim Akhtar, Shamim Akhtar; Zaheer Ali, Zaheer Ali; Muhammad Yahya Noori, Muhammad Yahya Noori; Ahsaan Ahmed, Ahsaan Ahmed (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-03-29)
    Mycobacterium tuberculosis is clinically recognized as a causative agent of Tuberculosis. Keeping in view, this study was endeavored to screen our previously synthesized seventeen INH analogues for their antimycobacterial ...
  • Free radical scavenging activity of Telfairia occidentalis extracts and their effects on iron-sulphate induced lipid per oxidation 
    Temitope, Adedosu Olaniyi; Emmanuel, Adeleke Gbadebo; Akintola, Adebola Olayemi; Olabode, Fatoki John; Isaac, Adelusi Temitope (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-03-28)
    Non-enzymic natural antioxidants of plant origin are known to play a key role in inflammation linked with free radicals and oxidative stress. This study investigates the free radical scavenging activity of various Telfairia ...
  • Analgesic, anti-inflammatory and diuretic activities of Cicer arietinum L. 
    Darakhshan Masroor, Darakhshan Masroor; Baig, Sadia Ghousia; Salman Ahmed, Salman Ahmed; Syed Muzzammil Ahmad, Syed Muzzammil Ahmad; Muhammad Mohtasheem ul Hasan, Muhammad Mohtasheem ul Hasan (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-03-27)
    Analgesic, anti-inflammatory and diuretic activities of the methanol extract of two varieties of Cicer arietinum viz black or Desi and white or Kabuli were tested in the doses of 200 and 400 mg/kg. For analgesic effect ...
  • Effects of Qibaipingfei capsules on pulmonary vascular relaxation through KATP channel activation by the NO/cGMP signaling pathway 
    Zhu, Jie; Wang, Baoqin; Lu, Mei; Tong, Jiabing; Yang, Jiabing; Li, Zegeng (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-03-26)
    This research explores the effects of Qibaipingfei (QBPF) capsules on pulmonary vascular relaxation in vitro and the relationship of the ATP-sensitive K+ (KATP) channel and nitric oxide (NO) pathway. Vasodilator effects ...

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