Volume: Recent submissions

  • Stability indicating RP-HPLC method of dexibuprofen in nanocream formulation: Identification and quantification 
    Munir, Rabia; Syed, Haroon; Asghar, Sajid; Shahid Iqbal, Muhammad; Irfan, Muhammad; Ullah Khan, Ikram; A Shah, Pervaiz; Khalid, Ikrima; Imran, Kashif; Saleem, Muhammad (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-07-08)
    A stability indicating reverse phase-HPLC method was designed for determination of dexibuprofen in drug solution and in nanocream formulation. Chromatographic conditions were optimized simply by adjusting the content and ...
  • Berberis lycium Royle. extracts attenuate inflammation and modulates hyperglycemia in alloxan induced diabetic rats 
    Zaib, Maryam; Sharif, Ali; Akhtar, Bushra; Majeed Khan, Humaira; Furqan Akhtar, Muhammad; Hassan, Waseem; Razzaq, Faisal; Nawaz, Sajid; Qaisar, Naeem (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-07-07)
    Berberis lycium Royle (Berberidaceae) is traditionally used for the treatment of diabetes mellitus. Present study was conducted to determine the antioxidant, antidiabetic and anti-inflammatory effects of aqueous and ...
  • Effect of lithium chloride on d-galactose induced organs injury: Possible antioxidative role 
    Samad, Noreen; Bilal, Kainat; Yasmin, Farzana; Khaliq, Saima; Zaman, Aqal; Mazhar Ayaz, M (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-07-06)
    The aging process is concerned with oxidative stress and causing malfunction of various organs such as the liver, kidney and heart. Lithium (Li) salts have shown anti-manic, anti-suicidal, and antioxidant properties. The ...
  • Raisins: A kitchen cabinet item can restores the liver function and structure 
    A. Qureshi, Shamim; Imran, Uzma; Lateef, Tooba; Bilal Azmi, Muhammad; Rais, Sumera; Akram Mudassir, Hina; Jahan, Musarrat; Muhammad Shabib Zaidi, Syed; Badar, Rabia; Ahmed, Dildar (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-07-05)
    The aqueous methanol extract of raisins (Vitis vinifera) was investigated in carbon tetrachloride (CCl4)induced hepatotoxic rats model. Where it was found to revert the alteration induced by CCl4 in liver structure and ...
  • In-silico computational analysis of [6-(2, 3-Dichlorophenyl)-1, 2, 4Triazine-3, 5-Diamine] metal complexes on voltage gated sodium channel and dihydrofolate reductase enzyme 
    Najm, Saima; Naureen, Humaira; Sultana, Kishwar; Anwar, Fareeha; Rehman, Sarah; Arshad, Shumaila; Mubbashir Khan, Muhammad (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-07-04)
    Epilepsy is the disease associated with seizures and convulsions. Various antiepileptic drugs have been used widely to treat these disorders. Lamotrigine [6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine] shows certain ...
  • Pharmacogenetics of sulfonylurea: Presence of CYP2C9*2, CYP2C9*3 and a novel allele, CYP2C9*61, in Type 2 diabetes patients under sulfonylurea therapy 
    Deen Muhammad, Sumaira; Khan, Hazar; Hussain, Mushtaq; Fatima Zeb, Tehseen; Kumar, Darshan; Rahi, Rahimullah; Asif, Mahayrookh; Ali Balooch, Akhter (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-07-03)
    CYP2C9 is an important member of the cytochrome P450 gene family involved in the metabolism of 15% of the drugs including an oral antidiabetic agent sulfonylurea. This study aims to investigate the frequency of CYP2C9*2 ...
  • Assessment of Antiviral combination therapy with Cephalosporin antibiotic for prevention of severe Influenza-A (H1N1)pdm09 infection associated secondary bacterial infection and other complications 
    Athar Ishaqui1, Azfar; Hayat Khan, Amer; Azhar Syed Sulaiman, Syed; Alsultan, Muhammad; Khan, Irfanullah (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-07-02)
    Secondary bacterial infection is considered as a major complication associated with severe Influenza-A (H1N1)pdm09 infection responsible for the mortalities and morbidities worldwide. Use of antibiotics in viral Influenza ...
  • Effect of varying quantities of polymer on preparation and stability evaluation of carbamazepine cocrystals with dicarboxylic acid coformers 
    Wasim, Muhammad; Mannan, Abdul; Ullah, Kalim; Arfat Yameen, Muhammad; Latif, Muhammad; Ahmad, Taseer; Ullah, Majeed; Imran Amirzada, Muhammad; Ullah Khan, Hafeez; Maheen, Safirah; Ali Khan, Shujaat; Adnan Jamil7, Qazi; Hassham Hassan Bin Asad, Muhammad; Hussain, Izhar (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-07-01)
    The current study is an attempt to explore the effect of varying quantities of hydroxypropyl cellulose (HPC) polymer on carbamazepine (CBZ) cocrystal formation with dicarboxylic acid coformers i.e., malonic acid (MA), ...
  • Herbs, Immunity and nCOVID-19: Old performers in new Pandemic 
    Naeem, Sadaf; Ikram, Rahila; Shareef, Huma; Ali, Huma; Saeed Khan, Saira (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-08-09)
    The novel coronavirus (nCOVID-19) has spread to endless nations and turn out to be a pandemic around the globe. Because of the developing number of affirmed cases and open public hazard owing to its high risk of infection ...
  • Impact of COVID-19 in public health: Prevalence and preventive approaches 
    Subramaniyan, Vetriselvan; Chakravarthi, Srikumar; Yuan Seng, Wu; Kayarohanam, Saminathan; Kumar Fuloria, Neeraj; Fuloria, Shivkanya (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-08-08)
  • Emerging pharmacy services; Recommendations for emergency care of COVID-19 pandemic in low and middle-income countries 
    Hamid, Husnain; Ali Masood, Rizwan; Khalid, Wahab; Saqlain, Muhammad; Tariq, Hira; Usman Munir, Muhammad (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-08-07)
    The ongoing outbreak of coronavirus diseases (COVID-19) has been declared as Pandemic by the World Health Organization and now become a global health emergency. Low and Middle income-countries lack standard pharmacy services ...
  • Causes and treatment of Covid-19: Myths vs Facts 
    Mudarab Ali, Syed; Hashmi, Ammara; Hussain, Tanveer (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-08-06)
    The world is facing a new pandemic called COVID-19. It started in December 2019 in Wuhan, China and in a few months it spread to almost every country of the world. Caused by a new streak of Coronavirus, it develops into ...
  • Treatment and control strategies for COVID-19: Prospects and possibilities 
    Khan, Kinza; Yaqub, Tahir (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-08-05)
    COVID-19 is a highly contagious and infectious disease, spreading rapidly worldwide. Its high spread rate has turned it into public stigma. The current study is focusing on its treatment and control strategies on the basis ...
  • Molecular structure and functions of zinc binding metallothionein-1 protein in mammalian body system 
    Hongfang, Guo; Guanghui, Cui; Khan, Rajwali; Huanxia, Jia; Jianxin, Zhang; Haidar Abbas Raza, Sayed; Ayaz, Muhammad; Shafiq, Muhammad; Zan, Linsen (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-08-04)
    Zinc a major trace element; perform diverse roles in genetics and physiology in almost every vital body system of the mammalian body. Zinc regulates the expression of almost all essential genes responsible for performing ...
  • Importance of vitamin D in cancer management 
    Irfan, Muhammad; Sajid Hamid Akash, Muhammad; Aun Muhammad, Syed; Rafique Ibrahim, Maryam; Imran Qadir, Muhammad (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-08-03)
    Vitamin D is essential element for growth and development of bones. The receptor of the metabolite of vitamin D known as “nuclear calcitriol” have been identified in tissues and is responsible for playing a wide range of ...
  • A case report of Meige syndrome-like blepharospasm caused by ingestion of allopurinol 
    LaiMin, Luo (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-08-02)
    One case of allopurinol-caused rare adverse reactions was reported. One male 51-year-old patient presented blurred vision, streaming eyes, photophobia and blepharospasm sequentially 1 week after oral administration of ...
  • Synthesis of new antibacterial agents encompassing tosyl, piperidine, propanamide and 1,3,4-oxadiazole functionalities 
    Sattar, Almas; Rehman, Aziz-ur; Athar Abbasi, Muhammad; Zahra Siddiqui, Sabahat; Rasool, Shahid; Adnan Ali Shah, Syed (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-08-01)
    A series of propanamide compounds 6a-l was derived by N-substitution reactions, encompassing tosyl, piperidine and 1,3,4-oxadiazole moieties. The intended array of compounds 6a-l was afforded by a series of five steps ...
  • Analgesic and neuropharmacological activities of Berberis lycium Royle collected from district Sherani Balochistan, Pakistan 
    Samiullah, Samiullah; Iqba, Javied; Khan, Amanullah; Muhammad, Shafi; Marvi, Marvi; Umer Jan, Syed; Gul, Rahman (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-07-31)
    Berberis lycium (family Berberidaceae) grows in district Sherani, Balochistan, Pakistan. It is used for the treatment of various disorders by the people of Balochistan. The present work was carried out to explore analgesic ...
  • Antinephrolithiatic activity of Ananas comosus extract against experimentally induced renal calculi in rats 
    A Sayed, Amany; R Fahmy, Sohair; M Soliman, Amel; M Mohamed, Dina (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-07-30)
    The present study evaluates the prophylactic role of Ananas comosus ethanolic extract (ACEE) against sodium oxalate (NaOx) - induced nephrolithiasis. Forty two rats were allocated into the following set of groups (6 rats/set ...
  • Chemical profiling, in vitro and in vivo bioactivities of leaf extracts of Vitex neugundo 
    Gul, Hina; Jabeen, Nyla; Irum, Samra; Kausar, Rehana; Ajab, Huma; Yaqub, Asim; Gulfraz, Muhammad (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-07-29)
    The Vitex negeundo is a widely used medicinal plant which has not been fully investigated in the past. We assessed the in vivo hepatoprotective and in vitro antioxidant, antibacterial, cytotoxicity and antiproliferative ...

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