Volume: Recent submissions

  • Curative effect of amlodipine combined with enalapril in curing hypertension of the aged 
    Li, Xiaowei; Zhang, Lihua; Jian, Liguo; Li, Li; Niu, Shaohui (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2015-03-06)
    This paper aims to research the clinical effect and security of using amlodipine and enalapril together to cure hypertension of aged people. Random number table was used to divide clinical data of 114 aged hypertensives ...
  • In vitro activity of antimicrobial agents against streptococcus pyogenes isolated from different regions of Khyber Pakhtun Khwa Pakistan 
    Rizwan, Muhammad; Bakht, Jehan; Bacha, Nafees; Ahmad, Bashir (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2016-01-20)
    The present study investigates the antibiotic resistance of S. pyogenes of 600 isolates collected from different body parts including throat and sputum were analyzed for their antimicrobial susceptibility to 5 antibiotics ...
  • Research on green supply chain coordination strategy for uncertain market demand 
    Cao, Jian; Chen, Yangyang; Lu, Bo; Tong, Chenlu; Zhou, Gengui (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2015-03-05)
    Based on the status that the green market began to develop (e.g. pharmaceutical industry) in Mainland China, the paper mainly discusses how members of the green supply chain (GSC) cooperate effectively in the process of ...
  • Molecular characteristics of extractives of Hylocereus undulates stems 
    Qingzhi, Ma; Furuta, Yuzo; Daochun, Qin; Dangquan, Zhang (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2015-03-04)
    As one of traditional and dominant species of famous fruits in South China, Hylocereus undulates is considered as the important fruit resources, however, the constituent properties of Hylocereus undulates stems have not ...
  • Role of the antidiabetic drugs: Glibenclamide and metformin on the contractility of isolated rat uteri 
    Elsayed Kelany, Mohamed; Alqahtani, Saeed; Alkuriji, Afrah; Yousef Al Omar, Suliman (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2016-01-20)
    The current investigation has designed to study the role of two antidiabetics, glibenclamide and metformin on the spontaneous uterine contractions in the non-diabetic non-pregnant female rats. The rat uteri were isolated ...
  • Variability of macroscopic dimensions of Moso bamboo 
    Cui, Le; Peng, Wanxi; Sun, Zhengjun; Lu, Huangfei; Chen, Guoning (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2015-03-03)
    In order to the macroscopic geometry distributions of vascular bundles in Moso bamboo tubes. The circumference of bamboo tubes was measured, used a simple quadratic diameter formula to analyze the differences between the ...
  • The acetylcholinesterase (AChE) inhibition analysis of medaka (Oryzias latipes) in the exposure of three insecticides 
    Zhu, Jianping; Huan, Cheng; Si, Guiyun; Yang, Haitang; Yin, Li; Ren, Qing; Ren, Baixiang; Fu, Rongshu; Miao, Mingsheng; Ren, Zongming (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2015-03-02)
    The continuous effects on Acetylcholinesterase (AChE) activity of medaka (Oryzias latipes) caused by dichlorvos, methomyl and deltamethrin in vivo were investigated, and the trends of AChE activity inhibition due to the ...
  • Antimicrobial profile of some novel keto esters: Synthesis, crystal structures and structure-activity relationship studies 
    Khan, Imtiaz; Saeed, Aamer; Arshad, Mohammad Ifzan; Michael White, Jonathan (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2016-01-20)
    Rapid increase in bacterial resistance has become a major public concern by escalating alongside a lack of development of new anti-infective drugs. Novel remedies in the battle against multidrug-resistant bacterial strains ...
  • Effects of psoralen on chondrocyte degeneration in lumbar intervertebral disc of rats 
    Yang, Libin; Sun, Xiaohui; Geng, Xiaolin (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2015-03-01)
    Discuss the internal mechanism of delaying degeneration of lumber intervertebral disc. The cartilage of lumbar intervertebral disc of SD rats was selected in vitro, then cultured by tissue explant method, and identified ...
  • Anti-ulcer activity of the aqueous extract of Melastoma malabathricum L. leaf in rats 
    Wan Zainulddin, Wan Noraziemah; Zabidi, Zalina; Kamisan, Farah Hidayah; Yahya, Farhana; Ismail, Noor Aisyah; Shamsahal Din, Nor Shafawati; Mamat, Siti Syariah; Hassan, Hadijah; Mohtarrudin, Norhafizah; Amiruddin Zakaria, d Zainul (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2016-01-20)
    Melastoma malabathricum L. Smith (Melastomaceae) has been used in the Malay traditional culture to treat ulcer-based ailments. The objective of the present study was to investigate the potential anti-ulcer effect of aqueous ...
  • Pharmacokinetic behavior of montelukast in indigenous healthy male volunteers 
    Fayyaz, Amtul; Khan, Junaid Ali; Ashraf, Muhammad Mudassar; Akhter, Naheed; Aslam, Bilal; Khalid, Muhammad Fiaz; Altaf, Sidra; Naseer, Rana Dawood; Akram, Muhammad; Shah, Syed Muhammad Ali; Khadam, Muhammad Waqas; Tahir, Imtiaz Mahmood (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2017-11-18)
    Aim of present study was to investigate the pharmacokinetic behavior of Montelukast in the healthy male volunteers under indigenous conditions. One tablet of montelukast 10 mg was administered in each subject and blood ...
  • Notch1 signaling activation protected myocardium against hypoxia injury via reducing programmed cell death 
    Hu, Yongjun; Zheng, Zhaofen; Pan, Hongwei; Peng, Jianqiang; Luo, Yangping; Cui, Bo; Zhong, Xin (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2017-11-17)
    Programmed cell death plays an important role in cardio protection, and Notch1 was an important factor related to programmed cell death. The role of Notch1 on ischemia myocardium remains unclear.H9C2 myocardial cells were ...
  • Dizocilpine induced psychosis-like behavior in rats: A possible animal model with full spectrum of schizophrenia 
    Shahzad, Sidrah; Ahmad, Saara; Madiha, Syeda; Khaliq, Saima; Liaquat, Laraib; Sadir, Sadia; Rafiq, Sahar; Tabassum, Saiqa; Batool, Zehra; Haider, Saida (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2017-11-16)
    Schizophrenia (SZ) is categorized as neuropsychiatric disorder with reduced lifespan and significant impairments in social and vocational functioning. One of the best proposed pharmacological animal models is dizocilpine, ...
  • Synthesis and antibacterial screening of S-substituted derivatives of 5-(3,4-methylenedioxyphenyl)-1,3,4-oxadiazol-2-thiol 
    Siddiqa, Asia; Rehman, Aziz-ur; Abbasi, Muhammad Athar; Siddiqui, Sabahat Zahra; Rasool, Shahid; Sattar, Almas; Muhammed Khan, Khalid; Ahmad, Irshad; Afzal, Saira (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2016-01-20)
    The most emerging class among the heterocyclic compounds is 1,3,4-oxadiazoles for their diverse biological activities. In the present research work, piperonylic acid (1) was converted consecutively into corresponding ester ...
  • MRSA: Prevalence and susceptibility pattern in health care setups of Karachi 
    Siddiqui, Tuba; Muhammad, Iyad Naeem; Khan, Muhammad Naseem; Naz, Shazia; Bashir, Lubna; Sarosh, Nosheen; Masood, Rida; Ali, Aatka; Fatima, Sakina; Naqvi, Talat (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2017-11-15)
    This assessment aims to determine the prevalence of methicillin resistance and multidrug resistance (MDR) among the clinical isolates of Staphylococcus aureus and antimicrobial susceptibility profile of methicillin resistant ...
  • Cytotoxic and acute toxicity studies of isoniazid derivatives 
    Naeem, Sabahat; Akhtar, Shamim; Lei, Zi-Ning; Lu, Kimberly; Zafar, Shaista; Ahmed, Ahsaan; Ali, Mohsin; Ahmed, Mansoor; Chen, Zhe-Sheng (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2017-11-14)
    Cancer is ultimately the result of cells that hysterically grow and do not die. Cells can experience uncontrolled growth if there are mutations to DNA, and therefore, alterations to the genes involved in cell division. ...
  • A Comparative biochemical study on two marine endophytes, Bacterium SRCnm and Bacillus sp. JS, Isolated from red sea algae 
    Ahmed, Eman Fadl; Mokhtar Hassan, Hossam; Ezzat Rateb, Mostafa; Abdel-Wahab, Noha; Sameer, Somayah; Ebel, Rainer; Aly Taie, Hanan Anwar; Sayed Abdel Hameed, Muhammad; Hammouda, Ola (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2016-01-20)
    Two marine endophytic bacteria were isolated from the Red Sea algae; a red alga; Acanthophora dendroides and the brown alga Sargassum sabrepandum. The isolates were identified based on their 16SrRNA sequences as Bacterium ...
  • The role of Glutathione, Cysteine and D-Penicillamine in exchanging Palladium and Vanadium metals from albumin metal complex 
    Mukhtiar, Muhammad; Jan, Syed Umer; Ullah, Ihsan; Hussain, Abid; Ullah, Izhar; Gul, Rahman; Ali, Essa; Jabbar, Abdul; Kuthu, Zulfiqar Hussan; Wasim, Muhammad; Khan, Muhammad Farid (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2017-11-13)
    Thiol groups are extensively present across biological systems being found in range of small molecules (e.g. Glutathione, Homo-cysteine) and proteins (e.g. albumin, haemo-globin). Albumin is considered to be a major thiol ...
  • Metal complexes of isonicotinylhydrazide and their antitubercular activity 
    Ali, Mohsin; Ahmed, Mansoor; Hafiz, Saleem; Kamal, Mustafa; Mumtaz, Majid; Hanif, Muhammad; Khan, Khalid Mohammed (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2017-11-12)
    The development and spreading of Multi Drug Resistant TB strains is hampering endeavours for the control and administration of tuberculosis (TB). The expansion episodes of multi-medication safe strains of Mycobacterium ...
  • Antimicrobial and toxicological studies on fruit pulp of Citrullus colocynthis L. 
    Shaikh, Jahanzeb; Shaikh, Dilnawaz; Rahman, Asif Bin; Shafi, Sumaira (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2016-01-20)
    The methanolic extract of dried fruit pulp of Citrullus colocynthis (Cucurbitaceae) has been studied with respect to antimicrobial and toxicological properties. The antimicrobial profile was investigated against thirty ...

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