PASTIC Dspace Repository

Browsing Volume 34 by Title

Browsing Volume 34 by Title

Sort by: Order: Results:

  • Hepatoprotective and hypolipidemic activities of Caesalpinia bonduc seed kernels and Gymnema sylvestre leaves extracts in alloxan-induced diabetic rats 
    Kousar, Shaneel; Aslam, Bilal; Muhammad, Faqir; Khan, Junaid Ali (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2021-01-16)
    The objective of the current research was to validate the hepatoprotective and anti-hyperlipidemic activities of C. bonduc seed kernels (CBSK) and G. sylvestre leaves (GSL) hydro-methanolic extracts, separately and in ...
  • Identification and structural investigation of potential novel drug candidates against lethal human pathogen 
    Hamid, Mehwish; Aurangzeb, Sana; Rashid, Yasmeen; Khan, Khalid Mohammed; Hameed, Abdul (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2021-01-16)
    Neisseria meningtidis is responsible for causing meningococcal meningitis along with acute septicaemia in human beings. Functional genomics strategies proved cruciality of certain genes/proteins in Neisseria meningitidi ...
  • Immunoinformatics approaches to explore B and T cell epitope-based vaccine designing for SARS-CoV-2 Virus 
    Bashir, Zohaib; Ahmad, Syed Umair; Kiani, Bushra Hafeez; Jan, Zainab; Khan, Nayab; Khan, Umama; Ihteshamul Haq; Zahir, Fazli; Qadus, Amara; Mahmood, Tariq (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2021-01-16)
    SARS-CoV-2, a new world coronavirus belonging to class Nidovirales of Coronaviridae family causes COVID-19 infection which is the leading cause of death worldwide. Currently there are no approved drugs and vaccines available ...
  • In vitro antioxidant potential and antiproliferative activity of Aesculus indica seed extract against hepatocellular carcinoma cell line 
    Shahbaz, Hina; Latif, Abida; Perveen, Sadia; Hussain, Khalid; Azam, Shamaila; Shaukat, Ayisha; Bukari, Nadeem Irfan; Tayyeb, Asima (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2021-01-16)
    Therapeutic secondary metabolites have gained immense attention in recent years due to their effective medicinal properties. Aesculus indica is a medicinally important plant being traditionally used for various ailments. ...
  • In vivo antioxidant potential of fruit mucilage from two varieties of Cucumis melo subsp. agrestis against oxidative stress induced toxicity 
    Rehman, Saira; Ishtiaq, Saiqa; Bukhari, Nadeem Irfan (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2021-07-20)
    To evaluate in-vivo antioxidant potential of fruit mucilage from Cucumis melo variety momordica (PM) and variety agrestis (KM) using rats as experimental animals, the fruits were collected, identified, dried and ...
  • In-silico three dimensional structure prediction of important Neisseria meningitidis proteins 
    Ali, Muhammad; Aurongzeb, Muhammad; Rashid, Yasmeen (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2021-03-09)
    Pathogenic bacteria Neisseria meningitidis cause serious infection i.e. meningitis (infection of the brain) worldwide. Among five pathogenic serogroups, serogroup B causes life threatening illness as there is no effective ...
  • Insights into Off-Label therapeutic strategies against mild and severe COVID-19 infection 
    Arshad, Bushra; Iqbal, Tahira; Bhatti, Khalid Pervez; Ahmed, Sheraz; Zaman, Wajid; Fazal Ullah; Nazeer, Amna; Saqib, Saddam (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2021-07-20)
    Currently, prevention and control of the coronavirus disease pneumonia epidemic situation are grim globally. To cope with total sheer carriers and patients of COVID-19 requires intensive medical support and adjunctive ...
  • Investigation of gastric microbiota in patients with coronary atherosclerosis disease infected by Helicobacter pylori 
    Qin, Heping; Wei, Tianling; Yi, Ping; Shi, Zhe; Wan, Min; Li, Wei; Xia, Yangchao; Luo, Yihui; Lian, Haiyan; Liu, Ning (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2021-11-07)
    Gastric microbiota may be involved in the pathogenicity of Helicobacter pylori(Hp). In the present study, 30 male patients with coronary atherosclerosis disease (CAD) infected with Hp and 30 healthy male volunteers with ...
  • IR study of degradation of acetaminophen by iron nano-structured catalyst 
    Altaf, Iqbal; Azmat, Rafia (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2021-01-16)
    Full degradation of acetaminophen (paracetamol) in aqueous solution was investigated at room temperature through heterogeneous iron nano-structured as catalyst in this article. Iron Nano-structured was prepared through ...
  • Isolation of new phytometabolites from Alpinia galanga willd rhizomes 
    Sharma, Pradeep Kumar; Fuloria, Shivkanya; Ali, Mohammed; Singh, Amit; Kushwaha, Shekhar Prakash; Sharma, Vijay Kumar; Subramaniyan, Vetriselvan; Fuloria, Neeraj Kumar (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2021-07-20)
    The current research was aimed to isolate newer phyto-metabolites from rhizomes of Alpinia galanga plant. Study involved preparation of Alpinia galanga rhizome methanolic extract, followed by normal phase column chromatography ...
  • Isolation, identification, and antimycotic activity of plumbagin from Plumbago europaea L. roots, leaves and stems 
    Jaradat, Nidal; Khasat, Ahmad Ibrahim; Al-Maharik, Nawaf; M Eid, Ahmad; Jundi, Waheed; Zatar, Nidal Abd Aljaber; Shtayeh, Mohammed Saleem Ali; Jamous, Rana (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2021-07-20)
    Plumbago europaea L. is a plant utilized in Palestinian ethnomedicine for the treatment of various dermatological diseases. The current investigation was designed to isolate plumbagin from P. europaea leaves, roots and for ...
  • Less disease severity of COVID-19 among smokers: An indication of investigating nicotine as preventive measure 
    Ghayyur, Aysha; Hussain, Syed Shahzad; Salam, Emaan; Saeed, Subhan; Shahid, Saman; Tanvir Us Salaam (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2021-01-16)
    The study was aimed to mention the epidemiology of smoking in Pakistani COVID-19 infected patients along with the disease severity, oxygen dependency and fatality rate. A cross sectional epidemiological study was carried ...
  • The mouse model of hepatic veno-occlusive disease 
    An, Licai; Li, Xijing; Chu, Xiaoxia; Liu, Xiaoqian; Zhang, Yuanfeng; Wang, Yanming; Wang, Yan; Liu, Yinghui (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2021-11-02)
    With the application of hematopoietic stem cell transplantation, Subacute or acute increase in the incidence of hepatic veno-occlusive disease (HVOD) becomes more common and it can lead to fatal complications. This article ...
  • Nanobiotechnology: Cradle for revolution in drug carrier systems 
    Zafar, Saba; Rasul, Akhtar; Iqbal, Muhammad Shahid; Rasool, Maria; Ahmed, Bilal; Qadir, Muhammad Imran (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2021-01-16)
    : The role of nanobiotechnology in the treatment of diseases is limitless. In this review we tried to focus main aspects of nanotechnology in drug carrier systems for treatment and diagnosis of various diseases such as ...
  • Neurochemical and behavioral effects of lorazepam: A dose related study 
    Ikram, Huma; Atique, Iqra; Perveen, Shahla; Zakir, Rumaisa; Haleem, Darakhshan J (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2021-01-16)
    Present study was designed to monitor the dose dependent effects of lorazepam; a benzodiazepine (CNS depressant). It is the primary drug of choice for treatment of anxiety and to produce calming effects. However, ...
  • Neuroprotective and antioxidant effect of Curcuma longa (Rhizome) methanolic extract on SH-SY5Y cells and Javanese medaka 
    Hassan, Ibrahim Maina; Ibrahim, Wan Norhamidah Wan; Yusuf, Ferdaus Mohamat; Ahmad, Siti Aqlima; Ahmad, Syahida (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2021-01-16)
    Diseases caused by oxidative stress can be prevented by antioxidant. Current treatments for those neurodegenerative diseases are not effective and cause many side effects. Thus, the search for alternative medicines is ...
  • Neuroprotective role of a monoterpene (thymol) on diazepam induced withdrawal symptoms in rats 
    Saleem, Sadia; Naqvi, Fizza; Batool, Asma; Naqvi, Sajjad Haider; Naqvi, Faizan; Batool, Zehra; Tabassum, Saiqa; Haider, Saida (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2021-07-20)
    : Benzodiazepine administration is known to be related to tolerance and a withdrawal syndrome on sudden cessation. Thymol possesses multiple biological properties especially in the pathogenesis of different brain ...
  • New series of hydrazinyl thiazole derivatives of piperidin-4-one: Synthesis, structural elucidation, analgesic activity and comparative structure activity relationship 
    siddiqui, Rubina; Akhter, Shamim; Haider, Shazia; Saify, Zafar Saied; Akhtar, Mahwish; Shamim, Sana (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2021-07-20)
    Seven new hydrazinyl thiazole derivatives of piperidin-4-one (PE3-PE9) have been synthesized by cyclization of intermediate thiosemicarbazone derivative (PE2). Parent molecule (PE1) was synthesized by one pot total ...
  • Optimization of chitosan for microencapsulation of flaxseed oil through spray drying 
    Kanwal, Sidra; Hafeez-ur-Rahman, Muhammad; Hussain, Ali; Nadeem, Muhammad; Abbas, Farzana; Akram, Muhammad; Inayat, Muhammad; Ali, Kashif (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2021-07-20)
    The study is aimed to characterize the wall material chitosan in combination with maltodextrin for microencapsulation of flaxseed oil to enhance the delivery of polyunsaturated fatty acids in functional foods. Four formulations ...
  • Optimization of empagliflozin immediate release tablets (10 mg) using central composite rotatable design with response surface methodology 
    M. Hanif, Anas; Bushra, Rabia; Iffat, Wajiha; Ghayas, Sana; Perveen, Shaheen; Riaz, Humayun; Alam, Shazia; Ali, Syed Imran; Ismail, Nahlah Elkudssiah; Zeb-un-Nisa (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2021-07-20)
    Empagliflozin is a selective inhibitor of sodium glucose co-transporter II, given as mono therapy or an add-on treatment to reduce the glycated hemoglobin levels in type 2 diabetes. This work deals with designing, formulating ...

Search DSpace


Advanced Search

Browse

My Account