Volume 33: Recent submissions

  • Ultrasonic-assisted extraction and antioxidant activity of polysaccharides from Eucommia ulmoides leaf 
    Liu, Mengpei; Lu, Wang; Ku, Kang-mo; Lei, Lili; Zong, Wei (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-16)
    Eucommia ulmoides is valuable medicinal plant in China. In this study, ultrasonic technology was used to extract polysaccharides and orthogonal design was applied to choose the optimal extraction conditions. The ...
  • Hematological complications under hyper conditions of glucose and distilled water 
    Hafeez Ullah; Akhtar, Munir; Hussain, Fayyaz; Ahmad, Ejaz; Ahmad, Mukhtar; Aziz, Muhammad Hammad; Andleeb, Farah; Batool, Zahida (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-16)
    This work presents a pilot method of hematological diagnosis about changes in: shape, size and rouleaux formation, cell count of leucocytes and platelet cells in the presence of different glucose [C6H12O6] and water ...
  • A comparative neurobehavioral study of sesame oil and fish oil on experimental animals 
    Naeem, Sadaf; Ali, Liaquat; Rizwani, Ghazala H; Ikram, Rahila; Khan, Saira Saeed; Shareef, Huma; Younus, Ishrat; Malick, Tabinda Zareen; Aleem, Umer (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-16)
    Natural oils are enriched with polyunsaturated fatty acids (PUFAs) which are important for our health. Recent experimental data explained that PUFAs might have a beneficial effect on various brain functions such as anxiety, ...
  • Terpenoid-lupeol of red dragon fruit (Hylocereus polyrhizus) and its immunomodulatory activity 
    Wahdaningsih, Sri; Wahyuono, Subagus; Riyanto, Sugeng; Murwanti, Retno (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-16)
    Red dragon fruit (Hylocereus polyrhizus, (F.A.C. Weber) Britton and Rose) has been reported to have various biological activities such as antimicrobial, anti-hypercholesterolemia, anti-diabetes mellitus, cardiovascular ...
  • Relaxant activity of different fractions of fruits of Rosa moschata J. 
    Nabi, Muhammad; Ali, Niaz; Shams, Bilal; Ahmed, Ghayour; Shah, Muhammad Jalat; Shakir Ullah; Shoaib, Mohammad; Shah, Syed Wadood Ali (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-16)
    The current work is an attempt to know that in which fraction(s) the relaxant constituents of Rosa moschata concentrate. Crude methanolic extract of Rosa moschata was prepared as per our reported procedure. Sub fractions ...
  • Phytochemical, anti-inflammatory, anti-nociceptive and cytotoxic basis for the use of Haloxylon stocksii 
    Peerzada, Sohaib; Khan, Muhammad Tanveer; Akhtar, Muhammad Furqan; Saleem, Ammara; Hamid, Irfan; Sharif, Ali; Akhtar, Bushra; Ali, Sajid; Ahmed, Shoaib; Raza, Moosa (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-16)
    A halophytic plant, Haloxylon stocksii, is used to treat various inflammatory disorders traditionally. The present study was carried out to investigate the phytochemical parameters, anti-inflammatory, analgesic and ...
  • Light transmission properties of pharmaceutical liquid bottles and evaluation of their photoprotective efficacy 
    Sabah, Arif; Shah, Ali; Tanwir, Sidra; Arsalan, Adeel; Malik, Aysha; Ahmad, Iqbal (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-16)
    The light sensitive pharmaceutical dosage forms are well protected from light by packing in light protective bottles especially the colored glass and plastic bottles. In the present study the transmission characteristics ...
  • Synthesis, characterization, antibacterial, hemolytic and thrombolytic activity evaluation of 5-(3-chlorophenyl)-2-((N-(substituted)-2- acetamoyl)sulfanyl)-1,3,4-oxadiazole derivatives 
    Aziz-ur-Rehman; Khan, Samreen Gul; Bokhari, Tanveer Hussain; Anjum, Fozia; Akhter, Naheed; Rasool, Shahid; Shah, Syed Adnan Ali; Shahid, Muhammad; Arshad, Aneesa (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-16)
    A novel series of 5-(3-Chlorophenyl)-2-((N-(substituted)-2-acetamoyl)sulfanyl)-1,3,4-oxadiazole derivatives was efficiently synthesized and screened for antibacterial, hemolytic and thrombolytic activities. The molecule ...
  • Long term outcome of chronic myeloid leukemia patients treated with imatinib: Report from a developing country 
    Absar, Muhammad; Akhtar, Tanveer; Jameel, Abid; Mahmood, Amer; Ullah, Anhar; Aleem, Aamer; Qureshi, Kulsoom; Rehman, Noor; Iqbal, Zafar (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-16)
    The outcome of chronic myeloid leukemia has been greatly improved by the use of Imatinib (IM), a selective BCR/ABL kinase inhibitor. The aim of present study was to report long term follow-up & outcome of IM-treated ...
  • Synthesis, characterization and antimicrobial activity of norfloxacin based acetohydrazides 
    Walayat, Kamran; Ahmad, Matloob; Rasul, Azhar; Aslam, Sana; Anjum, Muhammad Naveed; Sultan, Sadia; Iqbal, Mazhar (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-16)
    The drug resistance phenomenon in microbes is resulting in the ineffectiveness of available drugs to treat the infections. Thus, there is a continued need to discover new molecules to combat the drug resistance ...
  • Evaluation of wound healing effects of Syzygium cumini and laser treaqtment in diabetic rats 
    Kazmi, Syed Asif Jahanzeb; Riaz, Azra; Akhtar, Naheed; Khan, Rafeeq Alam (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-16)
    This study was aimed to investigate the antioxidant effects of Syzygium cumini (S. cumini) seeds extract along with wound healing score in correlation to glutathione and blood glucose levels in diabetic rats. Sprague-Dawley ...
  • Relaxant activity of different fractions of fruits of Rosa moschata J. 
    Nabi, Muhammad; Ali, Niaz; Shams, Bilal; Ahmed, Ghayour; Jalat Shah, Muhammad; Ullah, Shakir; Shoaib, Mohammad; Ali Shah, Syed Wadood (Karachi:Pakistan Journal of Pharmaceutical Sciences, University of Karachi., 2020-12-15)
    The current work is an attempt to know that in which fraction(s) the relaxant constituents of Rosa moschata concentrate. Crude methanolic extract of Rosa moschata was prepared as per our reported procedure. Sub fractions ...
  • Light transmission properties of pharmaceutical liquid bottles and evaluation of their photoprotective efficacy 
    Sabah, Arif; Shah, Ali; Tanwir, Sidra; Arsalan, Adeel; Malik, Aysha; Ahmad, Iqbal (Karachi:Pakistan Journal of Pharmaceutical Sciences, University of Karachi., 2020-03-15)
    The light sensitive pharmaceutical dosage forms are well protected from light by packing in light protective bottles especially the colored glass and plastic bottles. In the present study the transmission characteristics ...
  • Synthesis, characterization, antibacterial, hemolytic and thrombolytic activity evaluation of 5-(3-chlorophenyl)-2-((N-(substituted)-2- acetamoyl)sulfanyl)-1,3,4-oxadiazole derivatives 
    Rehman, Aziz-ur-; Khan, Samreen Gul; Bokhari, Tanveer Hussain; Anjum, Fozia; Akhter, Naheed; Rasool, Shahid; Ali Shah, Syed Adnan; Shahid, Muhammad; Arshad, Aneesa (Karachi:Pakistan Journal of Pharmaceutical Sciences, University of Karachi., 2020-03-15)
    A novel series of 5-(3-Chlorophenyl)-2-((N-(substituted)-2-acetamoyl)sulfanyl)-1,3,4-oxadiazole derivatives was efficiently synthesized and screened for antibacterial, hemolytic and thrombolytic activities. The molecule ...
  • Long term outcome of chronic myeloid leukemia patients treated with imatinib: Report from a developing country 
    Absar, Muhammad; Akhtar, Tanveer; Jameel, Abid; Mahmood, Amer; Ullah, Anhar; Aleem, Aamer; Qureshi, Kulsoom; Rehman, Noor; Iqbal, Zafar (Karachi:Pakistan Journal of Pharmaceutical Sciences, University of Karachi., 2020-01-15)
    The outcome of chronic myeloid leukemia has been greatly improved by the use of Imatinib (IM), a selective BCR/ABL kinase inhibitor. The aim of present study was to report long term follow-up & outcome of IM-treated CML ...
  • Rosa brunonii Lindely fruit as a new protective agent evaluated against Rif/INH induced toxicity in rats 
    Ahmad, Ejaz; Jahangi, Muhammad; Akhtar, Zahid Mahmood; Ishtiaq, Saiqa; Mukhtar, Hamid; Haider, Hafiz Muhammad Faizan; Bukhar, Nadeem Irfan (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-21)
    Rosa brunonii L., a less investigated plant contains flavonoid glycosides and is used to treat stomach ailments, heart problems, and diabetes in folk. The crude extract of the plant possesses antioxidant activity. The ...
  • Exploration of clinical management system: Career ladders, working model and reforms; a cross sectional estimate from Karachi, Pakistan 
    Ali, Huma; Rafi, SM Tariq; ikram, Rahila; Zafar, Farya; Naeem, Sadaf; Rehman, Hina; Nawab, Amber; Baloch, Saba A.; Mallick, Neelam (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-21)
    Clinical and hospital pharmacy services are not just medical and pharmaceutical sciences but also occupy significant placement in healthcare system. Pakistan is a developing state with a huge prerequisite for changes in ...
  • The effects of TPL-PEI-CyD on suppressing performance of MCF-7 stem cells 
    Zhu, Yimin; Xu, Fuying (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-21)
    Triptolide, an ingredient of Tripterygium wilfordii, has been demonstrated to possess many biological activities such as immunomodulatory, antitumor activity in experiment. The purpose of this study was to survey the toxicity ...
  • Formulation of Phaseolus vulgaris L. cream and its characterization 
    Khan, Muhammad Tahir; Usman, Muhammad; Nawaz, Hafiz Awais; Rasheed, Huma; Khan, Rizwan Rasul; Anjum, Syed Muhammad Muneeb; Khokhar, Muhammad Imran; Akhtar, Naveed (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-21)
    Red kidney beans have antioxidant effect and thereby can help in skin smoothening, moisturizing, whitening and have anti-wrinkles effect. The study was based on the formulation of a stable w/o emulsion possessing extract ...
  • Pharmacological studies pertaining to spasmolytic, bronchodilator and vasodilating effect of Typha domingensis: An evidence-based approach 
    Mouqadus-Un-Nisa; Imran, Imran (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-21)
    This study was designed to analyze the pharmacological effects of Typha domingenesis crude 70% aqueousethanol extract of Typha domingensis (Td. Cr) in gastrointestinal, respiratory and vascular diseases. Rabbits (2.0-3.0 kg) and ...

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