Walayat, Kamran; Ahmad, Matloob; Rasul, Azhar; Aslam, Sana; Anjum, Muhammad Naveed; Sultan, Sadia; Iqbal, Mazhar(Karachi:Pakistan Journal of Pharmaceutical Sciences, University of Karachi., 2020-03-15)
The drug resistance phenomenon in microbes is resulting in the ineffectiveness of available drugs to treat the
infections. Thus, there is a continued need to discover new molecules to combat the drug resistance phenomenon. ...
Ibraheem, Farhat; Ahmad, Matloob; Ashfaq, Usman Ali; Aslam, Sana; Ali Khan, Zulfiqar; Sultan, Sadia(Karachi:Pakistan Journal of Pharmaceutical Sciences, University of Karachi., 2020-03-15)
: Pyrazoline and benzimidazoles derivatives have been widely studied due to their potential applications in the
medicinal field. In this research project, we have hybridized these two heterocyclic systems in the same ...
Kadir, Abdul; Ibrahim, Sadaf; Nawaid Shah, Syed Nudrat(Karachi:Pakistan Journal of Pharmaceutical Sciences, University of Karachi., 2020-03-20)
: The attenuation of cisplatin-induced acute kidney injury (AKI) in mice by N-(2-hydroxyphenyl) acetamide
(NA-2) and NA-2-conjugated gold nanoparticles (NA2-AuNPs) was investigated. Male BALB/c mice (n = 54) were divided ...
Pain is a physiological unpleasant sensation that associated with actual or potential tissue damage and affects
the major part of human population. Numerous modulatory system control pain through a complex process. The ...
Khan, Saeed Ahmad(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2020-01-29)
Gelatin nanoparticles have attracted substantial interest as drug delivery vehicle. The presence of many
functional groups in gelatin structure offer several opportunities for cross linking and targeting. However, there ...
Austroyunnane B, a highly oxidized guaianolide-type sesquiterpenoid isolated from the whole plants of
Artemisia austro-yunnanensis by our group, revealed significant inhibition against NO production on the model of ...
Hypertension is considered as a multifactorial disorder in which a numerous of physiological mechanism take
part to raise blood pressure The present study is carried out to study the serum and red blood cell electrolyte ...
Scorzonera have been confirmed to have potent bioactivity. Scorzonera mackmeliana (Asteraceae), the
endemic plant to Lebanon, has not yet been investigated. In the present study, we assessed the antibacterial activity of ...
Whey plays an important role in the sports nutrition because of high quality proteins and essential amino acid
profile. Nine formulations of sportsman drinks were made using Cheddar, Mozzarella and Paneer whey with normal ...
The current study focused on the development, optimization and pharmaceutical evaluation of a mouth
dissolving film of Escitalopram 5mg. The designing and optimization of the formulations have been carried out through ...
The purpose of this study was to determine the antioxidant activities and cytotoxic properties of the various
extracts of Syzygium malaccense leaves and its correlation with total phenolic content. To determine the ...
Solvent fractions (n-hexane, cholorofrom, methanol) and fractions containing sterols of Jolyna laminarioides
was evaluated in triton-induced and high-fat-diet induced hyperlipidemic rats. Oral administration of J. ...
Tigecycline (TGC) and cefoperazone/sulbactam (CPS) both have been shown good in vitro activity against
carbapenem-resistant Acinetobacter baumannii (CRAB) isolates. We aim to compare the efficacy of TGC versus CPS for ...
A series of new compounds (5a-q), derived from 5-(1-(4-nitrophenylsulfonyl) piperidin-4-yl)-4-phenyl-4H1,2,4-triazole-3-thiol (3) were proficiently synthesized to evaluate their biological activities. 1-(4-Nitrophenylsul ...
Peroxynitrite is known as a strong deleterious species that may readily trigger several geriatric diseases via
injuring cellular constituents. Proanthocyanidins, a biological flavonoids constituent of Pinus sylvestris L. ...
Humans are experiencing serious health issues like myocardial infarction and diabetes. Thrombosis is the
reason of myocardial infarction that may cause death. Bioactive compounds or enzymes can be used to dissolve the ...
Jung, Eunsoo; Jung, Wookwon; Park, Su-Bin; Kim, Chan-Sik; Kim, Jin Sook; Kim, Junghyun(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2020-01-17)
EGHB010 is a standardized herbal formula of the rhizome mixture of Paeonia lactiflora Pallas and
Glycyrrhiza uralensis Fisch. Neovascularization in the retina is a common pathophysiology of diabetic retinal
microvasculopathy ...
High performance liquid chromatography with UV/vis detection was optimized and validated for
simultaneous quantification of alprazolam with celecoxib and diclofenac sodium in pharmaceutical formulation and human serum. ...
This study aimed to develop hyaluronic acid (HA)-coated nanostructured lipid carriers (NLC) loaded
simultaneously with oleanolic acid (OA), ursolic acid (UA) and Ginsenoside Rg3 (Rg3), prepared by electrostatic attraction ...
Pancytopenia is classified as low blood cell count. Low levels of hemoglobin, red blood cells, white blood
cells and platelets are indicative of pancytopenic state. This pancytopenic state can be treatment (drug) or disease ...