Issue 2: Recent submissions

  • The improvement on the skin surface by a new type of dermocosmetic loaded plant extract: A split face skin topographic study 
    Ali, Atif; Akhtar, Naveed; Khan, Hira; Hassan Bin Asad, Muhammad Hassham; Ahmad, Zia (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-16)
    Various extrinsic and intrinsic origins slant skins and pledge evident vicissitudes of the skin surface. We explored the effects of dermocosmetic loaded medical Cannabis seed extract and evaluate the improvement on the ...
  • Influence of age and co-medication on the concentration and efficacy of valproic acid in Chinese epilepsy children 
    Wang, Yan; Hu, Wenqing; Li, Zhiping (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-16)
    Valproic acid (VPA) was a classic antiepileptic drug for fifty years. However, individual variability of plasma drug concentration was obvious in epilepsy patients and few researches focused on the relationship ...
  • Promising role of Metformin in reducing the viability of breast cancerous cells 
    Rizvi, Fatima; Alam, Mahboob; Asad, Farah (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-16)
    To evaluate the anticancerous effects of different dilutions of metformin were evaluated for in vitro anticancerous effects, primarily breast cancer cells (MCF-7, MDA-MB-231). This prospective experimental study was conducted ...
  • Effect of processing methods on xylitol-starch base co-processed adjuvant for orally disintegrating tablet application 
    Bin, Liew Kai; Helaluddin, Abdul Bashar Mohammed; Sarker, Md Zaidul Islam; Mandal, Uttam Kumar; Gaurav, Anand (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-16)
    : Orally disintegrating tablet (ODT) is a friendly dosage form that requires no access to water and serves as a solution to non-compliance. There are many co-processed adjuvants available in the market. However, there is ...
  • Quality, quantity and hematological disorders in blood under Ethanol analyte an in vitro study 
    Akhtar, Munir; Mehmood, Rubaida; Hafeez Ullah; Irfan, Muhammad (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-16)
    The purpose of this manuscript is to analyze the quantity, quality and disorders of blood components and blood parameters before and after addition of five different concentrations i.e. (0µl, 10µl, 20µl, 30µl and 40µl) ...
  • Design and development of ondansetron hydrochloride pH independent control released matrix tablets 
    Anilkumar, Adimulapu; Murthy, Talasila Eswara Gopala Krishna; Rani, Avula Prameela (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-16)
    The oral control drug delivery is the most acceptable delivery system for patient acceptance, industrial application and economical but still it has several challenges to design a dosage form. The gastro intestinal pHis ...
  • Synthesis of (4R)-thiazolidine carboxylic acid and evaluation of antioxidant potential 
    Begum, Nasreen; Anis, Itrat; Saeed, Syed Muhammad Ghufran; Ashraf, Seema; Choudhary, M. Iqbal (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-16)
    We report here the synthesis as well as antioxidant activity of a series of 2-aryl thiazolidine-4-carboxylic acids, including two novel derivatives. They were synthesized by nucleophilic cyclic condensation of ...
  • Ultrasonic-assisted extraction and antioxidant activity of polysaccharides from Eucommia ulmoides leaf 
    Liu, Mengpei; Lu, Wang; Ku, Kang-mo; Lei, Lili; Zong, Wei (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-16)
    Eucommia ulmoides is valuable medicinal plant in China. In this study, ultrasonic technology was used to extract polysaccharides and orthogonal design was applied to choose the optimal extraction conditions. The ...
  • Hematological complications under hyper conditions of glucose and distilled water 
    Hafeez Ullah; Akhtar, Munir; Hussain, Fayyaz; Ahmad, Ejaz; Ahmad, Mukhtar; Aziz, Muhammad Hammad; Andleeb, Farah; Batool, Zahida (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-16)
    This work presents a pilot method of hematological diagnosis about changes in: shape, size and rouleaux formation, cell count of leucocytes and platelet cells in the presence of different glucose [C6H12O6] and water ...
  • A comparative neurobehavioral study of sesame oil and fish oil on experimental animals 
    Naeem, Sadaf; Ali, Liaquat; Rizwani, Ghazala H; Ikram, Rahila; Khan, Saira Saeed; Shareef, Huma; Younus, Ishrat; Malick, Tabinda Zareen; Aleem, Umer (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-16)
    Natural oils are enriched with polyunsaturated fatty acids (PUFAs) which are important for our health. Recent experimental data explained that PUFAs might have a beneficial effect on various brain functions such as anxiety, ...
  • Terpenoid-lupeol of red dragon fruit (Hylocereus polyrhizus) and its immunomodulatory activity 
    Wahdaningsih, Sri; Wahyuono, Subagus; Riyanto, Sugeng; Murwanti, Retno (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-16)
    Red dragon fruit (Hylocereus polyrhizus, (F.A.C. Weber) Britton and Rose) has been reported to have various biological activities such as antimicrobial, anti-hypercholesterolemia, anti-diabetes mellitus, cardiovascular ...
  • Relaxant activity of different fractions of fruits of Rosa moschata J. 
    Nabi, Muhammad; Ali, Niaz; Shams, Bilal; Ahmed, Ghayour; Shah, Muhammad Jalat; Shakir Ullah; Shoaib, Mohammad; Shah, Syed Wadood Ali (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-16)
    The current work is an attempt to know that in which fraction(s) the relaxant constituents of Rosa moschata concentrate. Crude methanolic extract of Rosa moschata was prepared as per our reported procedure. Sub fractions ...
  • Phytochemical, anti-inflammatory, anti-nociceptive and cytotoxic basis for the use of Haloxylon stocksii 
    Peerzada, Sohaib; Khan, Muhammad Tanveer; Akhtar, Muhammad Furqan; Saleem, Ammara; Hamid, Irfan; Sharif, Ali; Akhtar, Bushra; Ali, Sajid; Ahmed, Shoaib; Raza, Moosa (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-16)
    A halophytic plant, Haloxylon stocksii, is used to treat various inflammatory disorders traditionally. The present study was carried out to investigate the phytochemical parameters, anti-inflammatory, analgesic and ...
  • Light transmission properties of pharmaceutical liquid bottles and evaluation of their photoprotective efficacy 
    Sabah, Arif; Shah, Ali; Tanwir, Sidra; Arsalan, Adeel; Malik, Aysha; Ahmad, Iqbal (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-16)
    The light sensitive pharmaceutical dosage forms are well protected from light by packing in light protective bottles especially the colored glass and plastic bottles. In the present study the transmission characteristics ...
  • Synthesis, characterization, antibacterial, hemolytic and thrombolytic activity evaluation of 5-(3-chlorophenyl)-2-((N-(substituted)-2- acetamoyl)sulfanyl)-1,3,4-oxadiazole derivatives 
    Aziz-ur-Rehman; Khan, Samreen Gul; Bokhari, Tanveer Hussain; Anjum, Fozia; Akhter, Naheed; Rasool, Shahid; Shah, Syed Adnan Ali; Shahid, Muhammad; Arshad, Aneesa (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-16)
    A novel series of 5-(3-Chlorophenyl)-2-((N-(substituted)-2-acetamoyl)sulfanyl)-1,3,4-oxadiazole derivatives was efficiently synthesized and screened for antibacterial, hemolytic and thrombolytic activities. The molecule ...
  • Long term outcome of chronic myeloid leukemia patients treated with imatinib: Report from a developing country 
    Absar, Muhammad; Akhtar, Tanveer; Jameel, Abid; Mahmood, Amer; Ullah, Anhar; Aleem, Aamer; Qureshi, Kulsoom; Rehman, Noor; Iqbal, Zafar (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-16)
    The outcome of chronic myeloid leukemia has been greatly improved by the use of Imatinib (IM), a selective BCR/ABL kinase inhibitor. The aim of present study was to report long term follow-up & outcome of IM-treated ...
  • Synthesis, characterization and antimicrobial activity of norfloxacin based acetohydrazides 
    Walayat, Kamran; Ahmad, Matloob; Rasul, Azhar; Aslam, Sana; Anjum, Muhammad Naveed; Sultan, Sadia; Iqbal, Mazhar (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-16)
    The drug resistance phenomenon in microbes is resulting in the ineffectiveness of available drugs to treat the infections. Thus, there is a continued need to discover new molecules to combat the drug resistance ...
  • Evaluation of wound healing effects of Syzygium cumini and laser treaqtment in diabetic rats 
    Kazmi, Syed Asif Jahanzeb; Riaz, Azra; Akhtar, Naheed; Khan, Rafeeq Alam (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-16)
    This study was aimed to investigate the antioxidant effects of Syzygium cumini (S. cumini) seeds extract along with wound healing score in correlation to glutathione and blood glucose levels in diabetic rats. Sprague-Dawley ...
  • Rosa brunonii Lindely fruit as a new protective agent evaluated against Rif/INH induced toxicity in rats 
    Ahmad, Ejaz; Jahangi, Muhammad; Akhtar, Zahid Mahmood; Ishtiaq, Saiqa; Mukhtar, Hamid; Haider, Hafiz Muhammad Faizan; Bukhar, Nadeem Irfan (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-21)
    Rosa brunonii L., a less investigated plant contains flavonoid glycosides and is used to treat stomach ailments, heart problems, and diabetes in folk. The crude extract of the plant possesses antioxidant activity. The ...
  • Exploration of clinical management system: Career ladders, working model and reforms; a cross sectional estimate from Karachi, Pakistan 
    Ali, Huma; Rafi, SM Tariq; ikram, Rahila; Zafar, Farya; Naeem, Sadaf; Rehman, Hina; Nawab, Amber; Baloch, Saba A.; Mallick, Neelam (Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi, 2020-03-21)
    Clinical and hospital pharmacy services are not just medical and pharmaceutical sciences but also occupy significant placement in healthcare system. Pakistan is a developing state with a huge prerequisite for changes in ...

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