Issue 4: Recent submissions

  • Herbs, Immunity and nCOVID-19: Old performers in new Pandemic 
    Naeem, Sadaf; Ikram, Rahila; Shareef, Huma; Ali, Huma; Saeed Khan, Saira (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-08-09)
    The novel coronavirus (nCOVID-19) has spread to endless nations and turn out to be a pandemic around the globe. Because of the developing number of affirmed cases and open public hazard owing to its high risk of infection ...
  • Impact of COVID-19 in public health: Prevalence and preventive approaches 
    Subramaniyan, Vetriselvan; Chakravarthi, Srikumar; Yuan Seng, Wu; Kayarohanam, Saminathan; Kumar Fuloria, Neeraj; Fuloria, Shivkanya (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-08-08)
  • Emerging pharmacy services; Recommendations for emergency care of COVID-19 pandemic in low and middle-income countries 
    Hamid, Husnain; Ali Masood, Rizwan; Khalid, Wahab; Saqlain, Muhammad; Tariq, Hira; Usman Munir, Muhammad (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-08-07)
    The ongoing outbreak of coronavirus diseases (COVID-19) has been declared as Pandemic by the World Health Organization and now become a global health emergency. Low and Middle income-countries lack standard pharmacy services ...
  • Causes and treatment of Covid-19: Myths vs Facts 
    Mudarab Ali, Syed; Hashmi, Ammara; Hussain, Tanveer (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-08-06)
    The world is facing a new pandemic called COVID-19. It started in December 2019 in Wuhan, China and in a few months it spread to almost every country of the world. Caused by a new streak of Coronavirus, it develops into ...
  • Treatment and control strategies for COVID-19: Prospects and possibilities 
    Khan, Kinza; Yaqub, Tahir (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-08-05)
    COVID-19 is a highly contagious and infectious disease, spreading rapidly worldwide. Its high spread rate has turned it into public stigma. The current study is focusing on its treatment and control strategies on the basis ...
  • Molecular structure and functions of zinc binding metallothionein-1 protein in mammalian body system 
    Hongfang, Guo; Guanghui, Cui; Khan, Rajwali; Huanxia, Jia; Jianxin, Zhang; Haidar Abbas Raza, Sayed; Ayaz, Muhammad; Shafiq, Muhammad; Zan, Linsen (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-08-04)
    Zinc a major trace element; perform diverse roles in genetics and physiology in almost every vital body system of the mammalian body. Zinc regulates the expression of almost all essential genes responsible for performing ...
  • Importance of vitamin D in cancer management 
    Irfan, Muhammad; Sajid Hamid Akash, Muhammad; Aun Muhammad, Syed; Rafique Ibrahim, Maryam; Imran Qadir, Muhammad (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-08-03)
    Vitamin D is essential element for growth and development of bones. The receptor of the metabolite of vitamin D known as “nuclear calcitriol” have been identified in tissues and is responsible for playing a wide range of ...
  • A case report of Meige syndrome-like blepharospasm caused by ingestion of allopurinol 
    LaiMin, Luo (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-08-02)
    One case of allopurinol-caused rare adverse reactions was reported. One male 51-year-old patient presented blurred vision, streaming eyes, photophobia and blepharospasm sequentially 1 week after oral administration of ...
  • Synthesis of new antibacterial agents encompassing tosyl, piperidine, propanamide and 1,3,4-oxadiazole functionalities 
    Sattar, Almas; Rehman, Aziz-ur; Athar Abbasi, Muhammad; Zahra Siddiqui, Sabahat; Rasool, Shahid; Adnan Ali Shah, Syed (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-08-01)
    A series of propanamide compounds 6a-l was derived by N-substitution reactions, encompassing tosyl, piperidine and 1,3,4-oxadiazole moieties. The intended array of compounds 6a-l was afforded by a series of five steps ...
  • Analgesic and neuropharmacological activities of Berberis lycium Royle collected from district Sherani Balochistan, Pakistan 
    Samiullah, Samiullah; Iqba, Javied; Khan, Amanullah; Muhammad, Shafi; Marvi, Marvi; Umer Jan, Syed; Gul, Rahman (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-07-31)
    Berberis lycium (family Berberidaceae) grows in district Sherani, Balochistan, Pakistan. It is used for the treatment of various disorders by the people of Balochistan. The present work was carried out to explore analgesic ...
  • Antinephrolithiatic activity of Ananas comosus extract against experimentally induced renal calculi in rats 
    A Sayed, Amany; R Fahmy, Sohair; M Soliman, Amel; M Mohamed, Dina (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-07-30)
    The present study evaluates the prophylactic role of Ananas comosus ethanolic extract (ACEE) against sodium oxalate (NaOx) - induced nephrolithiasis. Forty two rats were allocated into the following set of groups (6 rats/set ...
  • Chemical profiling, in vitro and in vivo bioactivities of leaf extracts of Vitex neugundo 
    Gul, Hina; Jabeen, Nyla; Irum, Samra; Kausar, Rehana; Ajab, Huma; Yaqub, Asim; Gulfraz, Muhammad (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-07-29)
    The Vitex negeundo is a widely used medicinal plant which has not been fully investigated in the past. We assessed the in vivo hepatoprotective and in vitro antioxidant, antibacterial, cytotoxicity and antiproliferative ...
  • The synergistic effect of Paeonia spp and Glycyrrhiza glabra on polycystic ovary induced in mice 
    Sadinpour, Ahmad; Sadat Seyedi, Zeynab; Arabdolatabadi, Abbas; Razavi, Yasaman; Ajdary, Marziyeh (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-07-28)
    Paeonia spp and Glycyrrhiza glabra were traditionally used to treat female hormonal problems. This study was conducted to investigate the effect of root extract of these plants on ovarian follicles after induction of ...
  • Pharmacokinetics and vasodilating effect study of beraprost sodium in healthy volunteers 
    Li, Pingli; Zhang, Rui; Yuan, Guiyan; Chen, Keguang; Liu, Huanjun; Wang, Yanyan; Sami Shaikh, Abdul; Wang, Benjie; Li, Rong; Guo, Ruichen (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-07-27)
    Currently beraprost sodium (BPS) is widely proposed to ameliorate the symptoms caused by chronic arterial occlusive disease. The objective of this study is to investigate the BPS pharmacokinetic characteristics, its ...
  • Authentication of various commercially available crude drugs using different quality control testing parameters 
    Fatima, Kaneez; Mahmud, Shaukat; Yasin, Hina; Asif, Rana; Qadeer, Kiran; Ahmad, Iqbal (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-07-26)
    The object of this study is to investigate the quality of various plant materials used in the preparation of herbal formulations using different methods of standardization to confirm their purity, safety and efficacy. ...
  • Antibacterial activity of usnic acid from Usnea longissima Ach. 
    Maulidiyah, Maulidiyah; Hadijah Sabarwati, Siti; Harjuliarto, Rikhal; Haris Watoni, Abdul; Nurdin, Muhammad (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-07-25)
    Isolation and identification of secondary metabolite from n-hexane fraction of lichen Usnea longissima Ach. and its bioactivity as antibacterial have been carried out. The isolation of chemical compounds was performed by ...
  • Impact of volatile oils from processed products of Schisandra chinensis fruits on a mouse model of allergic asthma 
    Gao, Hui; Wang, Xinya; Xu, Yue; Zhang, Shuang (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-07-23)
    We established a mouse model of allergic asthma by sensitizing with chicken ovalbumin. The volatile oils and decoctions from raw, wine- and vinegar-steamed Schisandra chinensis fruits were intragastrically administrated ...
  • Synthesis of some N-sulfonated derivatives of 1-[(E)-3-phenyl-2propenyl]piperazine as suitable antibacterial agents 
    Athar Abbasi, Muhammad; Ijaz, Mubashar; Rehman, Aziz-ur; Zahra Siddiqui, Sabahat; Adnan Ali Shah, Syed; Shahid, Muhammad; Fatima, Hina (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-07-22)
    In the planned research work, the nucleophilic substitution reaction of 1-[(E)-3-phenyl-2-propenyl]piperazine (1) was carried out with different sulfonyl chlorides (2a-g) at pH 9-10 to synthesize its different N-sulfonated ...
  • Mast cell activation, TLR4-NF-κB/TNF-α pathway variation in rats’ intestinal ischemia-reperfusion injury and Tongxinluo's therapeutic effect 
    Junxiu, Zhang; Yu, Feng; Yanyan, Hu; Yin, Zhang; Yi, Liu; Minghui, Yang; Shaodan, Li (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-07-21)
    This study was designed to investigate mast cell activation and related TLR4-NF-κB/TNF-α pathway variation in 3 and 7 days' rats intestinal I/R injury, and TXL's intervention effect. Rat intestine I/R injury was carried ...
  • Isolation of chemical constituents from Filago vulgaris and antiproliferative activity of the plant extract and its flavonoid against human tumor cell lines 
    Hajdú, Zsuzsanna; Forgo, Peter; Király, Gergely; Pinke, Gyula; Zupkó, István; Hohmann, Judit (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2020-07-20)
    Phytochemical investigation of the whole plant of Filago vulgaris Lam. (Asteraceae) resulted in the isolation and characterization of seven compounds, including a rare methoxylated flavonol (araneol), tetrahydrofurofuranolignans ...

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