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Browsing Volume 31 by Issue Date

Browsing Volume 31 by Issue Date

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  • Prostate cancer: Leading and misleading routes to TRAIL of death 
    Farooq, Ammad Ahmad; Qureshi, Muhammad Zahid; Abdur Rehman; Nogueira, Daniele Rubert; Awan, Imrana Iftikhar; Adeela Shahid (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2014-09-20)
    Prostate cancer is a multifaceted disease that arises because of misrepresentation of linear and integrated signaling cascades that regulate gene network in normal and cancer cells. Programmed cell death is modulated by ...
  • Renin Angiotensin Aldosterone System (RAAS): Its biology and drug targets for treating diabetic nephropathy 
    Maryam Zain; Awan, Fazli Rabbi (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2014-09-20)
    Diabetes mellitus is a multifactorial disorder of hyperglycemia caused by a combination of biochemical, molecular and genetic factors, which leads to the dysfunction of various organs including kidneys. Diabetic nephropathy ...
  • Zein based magnesium oxide nanoparticles: Assessment of antimicrobial activity for dental implications 
    Naguib, Ghada H; Khaled M Hosny, Khaled M Hosny; Ali H. Hassan, Ali H. Hassan; Faten Al Hazmi, Faten Al Hazmi; yman Al Dharrab, yman Al Dharrab; Hala M Alkhalid, Hala M Alkhalid; Mohamed T Hamed, Mohamed T Hamed; Abeer M Alnowaiser, Abeer M Alnowaiser; Pashley, David H (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-01-01)
    MgO nanoparticles have been recently discovered as an antibacterial, however, they limited by property degradation due to agglomeration. The addition of a coating agent, such as a zein polymer, is effective in preventing ...
  • Biosurfactants production potential of native strains of Bacillus cereus and their antimicrobial, cytotoxic and antioxidant activities 
    Madiha Basit, Madiha Basit; Muhammad Hidayat Rasool, Muhammad Hidayat Rasool; Naqvi, Syed Ali Raza; Muhammad Waseem, Muhammad Waseem; Bilal Aslam, Bilal Aslam (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-01-02)
    Present study was designed to evaluate the biosurfactant production potential by native strains of Bacillus cereus as well as determine their antimicrobial and antioxidant activities. The strains isolated from garden soil ...
  • Neurite outgrowth properties of Calotropis procera: In search for a neuroprotectant 
    Aisha Kamal, Aisha Kamal; Zafar Saeed Saify, Zafar Saeed Saify; Khawar Saeed Jamali, Khawar Saeed Jamali; Priya Tufail, Priya Tufail; Aiman Kanwal, Aiman Kanwal; Khan, Faisal; Sonia Siddiqui, Sonia Siddiqui (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-01-03)
    In view of the well-documented medicinal properties of Calotropis procera (CP), the present study was designed to evaluate the neuroprotective effect of the extract. We have prepared a methanolic extract of Calotropis ...
  • Effect of the serum of rats treated with Suo Quan pill on embryonic stem cells 
    Xu, Jing- Jing; Huang, Ping; Xiang, Yun-Ya; Tan, Bo; Wu, Qing-He; Ze-Hui Qin, Hong-Ying Cao (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-01-04)
    Suo Quan pill(SQP), a well-known and classical traditional Chinese medicine compound, consists of three traditional Chinese medicine: Alpinia oxyphylla Miq., Lindera aggregata (Sims) Kosterm., Dioscorea opposite. Its ...
  • Effects of Cordyceps sinensis on macrophage function in high-fat diet fed rats and its anti-proliferative effects on IMR-32 human neuroblastoma cells 
    Dos Santos, Leandro Freire; Rubel, Rosalia; Bonatto, Sandro Jose Ribeiro; Yamaguchi, Adriana Aya; Torres, Maria Fernanda; Soccol, Vanete Thomaz; Da Silva, Andre Luís Lopes; Soccol, Carlos Ricardo (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    Macrophages have been considered an elusive yet emerging therapeutic target in tumor development since they are an important component in tumor microenvironment. The purpose of the present study was to evaluate the effect ...
  • Pharmacological validation of the folkloric uses of Cyperus rotundus L. in different ailments: An in vivo and in vitro research 
    Hussain, Musaddique; Waqas, Hafiz Muhammad; Hussain, Ikhlaq; Majeed, Abdul; Raza, Shahid Masood; Janbaz, Khalid Hussain (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    In vivo and in vitro research study was conducted on Cyperus rotundus to evaluate the sound mechanistic background in the treatment of gastrointestinal, bronchial and vascular disorders as well as in pain, emesis, pyrexia ...
  • Prescribing pattern of angiotensin receptor blocker: A study of errors and drug-drug interactions 
    Nesar, Shagufta; Shoaib, Muhammad Harris; Rafiq, Kiran; Rahim, Najia; Muhammad, Iyad Naeem; Iffat, Wajiha (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    Prescriptions comprising multi-drug therapy mostly illustrate the prescribing error. The phenomenon of error is bonded with human inaccuracy. The erroneous practice is observed in under developed countries like Pakistan, ...
  • Antifungal and cytotoxic activities of selected medicinal plants from Malaysia 
    Chan, Yik Sin; Cheah, Yit Hong; Chong, Poh Zen; Lai Khor, Hui; Siang Teh, Wen; Khoo, Kong Soo; Chooi Ong, Hean; Weng Sit, Nam (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    This study was conducted to investigate the antifungal potential and cytotoxicity of selected medicinal plants from Malaysia. The extracts from the stem of Cissus quadrangularis and the leaves of Asplenium nidus, Pereskia ...
  • Squid ink polysaccharide prevents chemotherapy induced injury in the testes of reproducing mice 
    Luo, Ping; Liu, Hua-Zhong; Yan Le, Xiao; Du, Hui; Kang, Xin-Huang (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    The present study was conducted to investigate the preventive effects of squid ink polysaccharides (SIP) on the damage of sperm and reproduction induced by cyclophosphamide that is most commonly used for treating clinically ...
  • A clinical study showing altered antioxidants profile in patients with hypertension 
    Khan, Abad; Iqbal, Zafar (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    We compared the plasma antioxidants level of normal control group with that of hypertensive patients in order to test the hypothesis “that antioxidants level has been diminished in hypertensive patients and that antioxidants ...
  • Synthesis, optimization and biological evaluation of 99mTc-digoxin as possible cardiac imaging agent 
    Bokhari, Tanveer Hussain; Roohi, Samina; Hina, Saira; Saeed, Shabana (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    Heart imaging radiopharmaceuticals could improve the diagnostic value of routine heart scanning for detecting cardiac disorders. The aim of the study was to prepare high radiochemical purity 99mTc-Digoxin in a yield of ...
  • A study of serological markers and lipid profile in non-alcoholic liver cirrhosis patients 
    Khan, Sadaf; Jamal, Siddiqua (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    Cirrhosis is the end result of chronic liver damage, associated with altered serum biomarkers and lipid profile. However, only few studies regarding serum biomarkers and plasma lipid profile in non-alcoholic liver cirrhosis ...
  • Evaluation of antioxidant and antimicrobial activities of Bergenia ciliata Sternb (Rhizome) crude extract and fractions 
    Khan, Aman; Jan, Gul; Danish, Muhammad (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    Biologically, screening of medicinal plants extracts have been since pre-historic to determine the antioxidants and antimicrobial profile. The present study was aimed to investigate and evaluate crude extract and different ...
  • Antiulcer activity of methanol-chloroform extract of Channa striatus fillet 
    Azemi, Ahmad Khusairi; Abd Rahim, Mohd Hafiz; Mamat, Siti Syariah; Mat Jais, Abdul Manan; Zakaria, Zainul Amiruddin (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    Channa striatus (Haruan) is Malaysian freshwater fish that is traditionally used to treat ailments related to wound and also ulcers. The aimed of the present study was to determine the mechanisms of anti-ulcer activity of ...
  • Palladium glutathione, N-acetylcysteine, D-penicillamine conjugation chemistry 
    Muhammad Mukhtiar; Syed Umer Jan; Khan, Muhammad Farid; Naseem Ullah; Abid Hussain; Saif ur Rehman; Qureshi, Muhammad Murtaza (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    The metalloelement Palladium has a number of potential Pharmaco-clinical advantages. Palladium compounds have antiviral, antibacterial, neuroprotective and antitumor properties. However studies have also indicated some ...
  • Rapid diagnostic method of tobacco products in saliva by fourier transform infrared spectroscopy (FTIR) 
    Channa, Naseem Aslam; Kalhoro, Dost Muhammad; Jahangir, Taj Muhammad (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    The present study was designed to explore the easy and fast method diagnosis of tobacco products in saliva of tobacco users (TU) by FTIR. Sixty four male tobacco users (TU) with mean age range 15.3 to 30.7 years were ...
  • Safety of fenbendazole in common peafowl (Pavo cristatus) 
    Seema Abbas Sajid Umar; Khan, Muhammad Irfan; Qamar-un-Nisa; Muhammad Younus; Kiran Aqil; Rizwan Qayyum; Muhammad Yaqoob; Asif Ali; Yaseen, Muhammad Asif; Shah, Muhammad Ali (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    The present study was undertaken to find out the safety levels of fenbendazole in common peafowl. This bird, raised on aviaries and zoos, can be severely parasitized with Ascaridia galli (enteric worms) and Syngamus trachea ...
  • Effects of gamma irradiation on the physico-chemical and biological properties of levofloxacin 
    Saleem Raza; Yousaf Iqbal; Ihsan Ullah; Mubarak, Mohammad S; Hameed, Muhammad Usman; Muslim Raza (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    The aim of the present study was to examine the effect of gamma radiation on levofloxacin. Powder form of levofloxacin was subjected to different radiation doses (25, 50, 75, 100 and 125kGy) of Cobalt-60 source in ...

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