Volume 31: Recent submissions

  • Synthesis, characterization and evaluation of antibacterial activity of copper oxide nanoparticles against clinical strains of Staphylococcus aureus 
    Naheed Niaz; Asma Bano; Fehmida Fasim; Rehana Kausar; Khan, Barkat Ali; Naheed Zafar; Khan, Samiullah; Bushra Uzair (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-07-14)
    Bacterial resistance is spreading globally due to excessive use of antibiotics, making it one of our times biggest challenges. To address this issue present study was conducted to evaluate the antibacterial activity of ...
  • Anti-diabetic activity of aqueous extract of Ipomoea batatas L. in alloxan induced diabetic Wistar rats and its effects on biochemical parameters in diabetic rats 
    Shagufta Kamal; Naheed Akhter; Khan, Samreen Gul; Shumaila Kiran; Tahir Farooq; Muhammad Akram; Syed Muhammad Ali Shah; Imtiaz Mahmood Tahir; Muhammad Akhlaq; Fahad Said; Jawad Zaheer (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-07-13)
    Diabetes is a condition where the fasting blood glucose level elevated above the normal range (80-120mg/dL). This increase in blood glucose level may be due to the insulin deficiency i.e. insulin dependent diabetes mellitus ...
  • Piperine attenuates the cancerous activity response in Neuro-2a cell line 
    Sonia Siddiqui; Aiman Kanwal; Khawar Saeed Jamali; Priya Tufail; Aisha Kamal (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-07-12)
    Interactions of cancer cells with their microenvironment play a significant role in defining the severity of the disease. In search of novel compounds with anti-inflammatory and anticancerous capabilities, the effects of ...
  • Phytochemical screening, antioxidant and in vivo neuropharmacological effect of Monotheca buxifolia (Falc.) barks extract 
    Samiullah Burki; Mehjabeen; Zeba Gul Burki; Zafar Ali Shah; Muhammad Imran; Muhammad Khan (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-07-11)
    Owing to its pharmacological versatility, the current study focuses the evaluation of Monotheca buxifolia (M. buxifolia) bark crude extract and its fractions for phytochemical and pharmacological analysis. Phytochemical ...
  • Potent antioxidative DNA damage of selected Saudi medicinal plants in cultured human lymphocytes 
    Haytham Mahmoud Daradka; Omar Flah Khabour; Mohammad Kdaimes Alotaibi (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-07-10)
    Oxidative stress is a condition that might predispose the individuals to diseases including cancer. The 8- hydroxydeoxyguanosine (8-OHdG) is a marker that reflects oxidative DNA damage in the body. In this study, seven ...
  • Conventional versus microwave assisted synthesis, molecular docking and enzyme inhibitory activities of new 3,4,5-trisubstituted-1,2,4- triazole analogues 
    Naeem Akhtar Virk; Aziz-ur-Rehman; Abbasi, Muhammad Athar; Sabahat Zahra Siddiqui; Umer Rashid; Javed Iqbal; Muhammad Saleem; Muhammad Ashraf; Wardah Shahid; Syed Adnan Ali Shah (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-07-08)
    N-(Substituted)-5-(1-(4-methoxyphenylsulfonyl)piperidin-4-yl)-4H-1,2,4-triazol-3-ylthio) acetamide were synthesized by following conventional as well as microwave assisted protocol through five consecutive steps under the ...
  • Evaluation of 99mTc-sulfadiazine as Bacillus microorganisms infection imaging agent using animal model 
    Muhammad Tauqeer Ahmed; Muhammad Yameen; Bushra Munir; Sadia Asim; Muhammad Usman; Syed Ali Raza Naqvi; Jawad Akhtar Hussain Gillani; Rashid Rasheed; Muhammad Adeel Shahzad (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-07-08)
    Bacterial infection is one of the vital sources of morbidity and mortality. The development of single photon emission computed tomography (SPECT) radiotracer agents using antibiotics, for targeting in-vivo bacteria, helps ...
  • Development and validation of HPLC method for the determination of pioglitazone in human plasma 
    Syed Imran Ali; Nighat Razvi; Syed Mohammad Farid Hasan (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-07-07)
    Pioglitazone is widely used for the management of type–II diabetes mellitus. The objective of the present study was to develop a simple and cost-effective HPLC method for the quantification of pioglitazone in human plasma. ...
  • Efficacy of Azadirachta indica organic extracts against clinical methicillin resistant Staphylococcus aureus isolates 
    Jaweria Anwar; Muhammad Asif Zahoor; Muhammad Kashif Zahoor; Abu Baker Siddique; Zeeshan Nawaz; Muhammad Hidayat Rasool; Muhammad Usman Qamar; Muhammad Waseem; Syed Zajif Hussain; Aysha Yasmin (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-07-06)
    In current study we investigated the efficacy of organic extracts of Azadirachta indica leaves against Methicillin Resistant Staphylococcus aureus (MRSA) clinical isolates. For this purpose fresh leaves were used to prepare ...
  • Ameliorating role of methanolic leaves extract of Fraxinus xanthoxyloides against CCl4-challanged nephrotoxicity in rats 
    Tahira Younis; Azhar Rasul; Faiza Jabeen; Ghulam Hussain; Javaria Altaf; Laila Jafri; Rehana Rani; Khan, Muhammad Rashid; Iqra Sarfraz; Muhammad Ali (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-07-05)
    Roots, bark, stem/twigs, and leaves of Fraxinus xanthoxyloides are being used regionally for the cure of malaria, jaundice, internal injuries, pneumonia, pain, rheumatism and also in fracture of bones. Our objective was ...
  • Biowaiver studies of newly optimized meloxicam tablets 
    Farya Zafar; Khan, Sohail; Huma Ali; Shabana N. Shah; Rabia Bushra; Ghazala Raza Naqvi; Kashif Maroof; Khan, Maqsood Ahmed; Zeb un Nisa (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-07-04)
    In this research work biowaiver studies of newly developed and optimized Meloxicam 7.5mg and 15mg water dispersible formulations were carried out at different dissolution media i.e. 0.1N HCl, phosphate buffer pH 4.5, pH ...
  • Spectrophotometric investigation of Glutathione modulation by Thallium chloride in aqueous medium 
    Khan, Muhammad Jalil; Muhammad Mukhtiar; Qureshi, Muhammad Murtaza; Syed Umer Jan; IzharUllah; Abid Hussain; Khan, Muhammad Farid; Rahman Gul; Nisar Ahmad Shahwani4; Imran Rabbani (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-07-03)
    Thallium has been shown to significantly influence various tissues of living organisms; Exposure to Thallium can disturb mitochondrial function, degenerate neurons, and interfere with the function of critical metabolic ...
  • Antinociceptive, antimicrobial potential and phytochemical screening of different solvent extracted samples from the stem of Acer pentapomicum 
    Khan, Shehla; Jehan Bakht; Mohammad Shafi (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-07-02)
    The present study investigates the antinociceptive, antimicrobial activity and phytochemical assessment of samples from A. pentapomicum. Different microbes were tested using disc diffusion assay at three concentrations ...
  • Anti-inflammatory terpenoids from Cyperus rotundus rhizomes 
    Sabrin Ragab Mohamed Ibrahim; Gamal Abdallah Mohamed; Maan Talaat Abdullah Khayat; Mohamed Fathalla Zayed; El-Kholy, Amal Abd-Elmoneim Soliman (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-07-01)
    Phytochemical investigation of the methanolic extract of Cyperus rotundus L. (Cyperaceae) rhizomes afforded a new norterpenoid with an unprecedented carbon skeleton, namely cyperalin A (1) and sugetriol triacetate (2). ...
  • MINI REVIEW Chronic obstructive pulmonary disease, its new drug treatments and strategies: A review 
    Muhammad Hanif; Junaid Qureshi; Hira Ijaz; Muhammad Iqbal Mustafa; Akhtar Rasul; Naeem Amir; Basma Aftab; Ahad Fayyaz (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-06-02)
    COPD is a complicated disease. Current available treatments are just for symptomatic relief and they cannot reverse the damages to lungs tissues due to alveolar destruction in COPD. Research is being conducted to evaluate ...
  • REPORT An ex vivo up-take of levamisole molecules by cestode (Monezia expensa) of goat (Capra hirsa) and its detection through RP-HPLC 
    Muhammad Mazhar Ayaz; Muhammad Sajid; Das, Sanjota Nirmal; Muhammad Hanif (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-06-01)
    Detection of various molecules of drugs remained a prime issue especially in tissues of animals, humans and in their target parasites. The cestode/tapeworms pose a dilemma because of their weird body composition and uptake ...
  • REPORT Comparison of qualitative, quantitative analysis and antioxidant potential between wild and cultivated Borago officinalis leaves from palestine 
    Hassan Abu-Qaoud; Nuha Shawarb; Fatima Hussen; Nidal Jaradat; Munqez Shtaya (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-05-31)
    Borago officinalis plant is an important plant of high medicinal and nutritional values. This study designed to evaluate antioxidant activity, screen the existence of phytogenic chemical compounds and to determine the ...
  • REPORT Phytochemical screening and antimicrobial activities of red silk cotton tree (Bombax ceiba L.) 
    Syed Sadaqat Shah; Syed Salim Shah; Arshad Iqbal; Sajjad Ahmed; Khan, Wisal Muhammad; Saddam Hussain; Li, Zhijian (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-05-30)
    The present study was conducted to investigate the phytochemical screening and antimicrobial activities of stem bark of Bombax ceiba L. The methanol extract was subjected to qualitative phytochemical screening using ...
  • REPORT Insight into the lipophilicity of selected monosubstituted chalcones 
    Sandeep Sankaran; Balasubramanian, Ranganathan (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-05-29)
    This study represents our attempt to understand how the antimicrobial activity of chalcones is modulated by their lipophilicity. To achieve this overall objective, a library of monosubstituted chalcones was targeted after ...
  • Screening and characterization of selected drugs having antibacterial potential 
    Hina Javed; Sobia Tabassum; Shazia Erum; Iram Murtaza; Aish Muhammad; Farhana Amin; Muhammad Farrukh Nisar (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-05-27)
    Due to ever increasing antibiotic resistance offered by pathogenic bacterial strains and side effects of synthetic antibiotics, thereof, there is a need to explore the effective phytochemicals from natural resources. In ...

Search DSpace


Advanced Search

Browse

My Account