Volume 31: Recent submissions

  • Preparation of levodopa/carbidopa compound drug resins 
    Hongfei Liu; Hui Ding; Dandan Zhang; Fengsi; Changshan Sun (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    The main objective of this study was to prepare the levodopa/carbidopa compound drug resins and investigate affecting factors such as drug concentration, temperature, particle size. The drug resins were made by bath method ...
  • Effect of haloperidol on behavioral sensitization and cognition in methylphenidate and buspirone-methylphenidate co-administered rats 
    Nausheen Alam; Rahila Ikram (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-09-26)
    Attenuation of methylphenidate-induced behavioral sensitization and cognitive tolerance by buspirone coadministration has been reported previously. Dopamine D2-receptors are considered to be important in methylphenidateinduced ...
  • Anti-inflammatory effect of the compounds from the flowers of Trollius chinensis 
    Liu, Li-Jia; Hu, Xiu-Hua; Guo, Li-Na; Wang, Ru-Feng; Zhao, Qi-Tao (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-09-25)
    In order to investigate the anti-inflammatory activity of flavonoids, phenolic acids, and alkaloids from the flowers of Trollius chinensis, some representative compounds, namely, orientin, 2"-O-β-L-galactopyranosylorientin, ...
  • Disposition kinetics of omeprazole in healthy female volunteers in Pakistan 
    Sadia Ashraf; Tanweer Khaliq; Ijaz Javed; Bilal Aslam; Nazia Qadir; Nadia Noor (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    Omeprazole (OMP) a proton pump inhibitor is widely used to suppress gastric acid secretions of parietal cells of stomach and metabolized predominantly by CYP2C19. The objective of the present study was to investigate the ...
  • Effect of glycine: Studying memory and behavioral changes in mice 
    Samia Imtiaz; Mazhar Ayaz; Huma Ikram; Muhammad Imran Qadir; Syed Aun Muhammad (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-09-24)
    Glycine is an important chemical mediator of nervous system that plays a vital role in memory and other neurological functions. Therefore, the effect of glycine on these traits must be studied to understand biological mechanisms ...
  • Supplementation of garlic and coriander seed powder: Impact on body mass index, lipid profile and blood pressure of hyperlipidemic patients 
    Falak Zeb; Mahpara Safdar; Sadia Fatima; Khan, Saleem; Sahib Alam; Mumtaz Muhammad; Ayesha Syed; Fozia Habib; Hira Shakoor (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-09-23)
    Garlic and coriander play an obligatory role in the metabolism of lipids leading to the reduction of CVD development. We hypothesized that garlic, coriander and their mixture improves the lipid profile, BMI and blood ...
  • Prevalence of non alcoholic fatty liver and Non alcoholic Steatohepatitis in Peshawar Cantonment, Khyber Pakhtunkhwa, Pakistan 
    Shah, Abdus Saboor; Shahzeb Khan; Haroon Rahim; Chishti, Kamran Ahmad; Khan, Aamir Ghafoor (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    Non-alcoholic fatty liver disease prevalence has not been well established. The aims of this study was to define prospectively non-alcoholic steatohepatitis (NASH) and non-alcoholic fatty liver disease (NAFLD) prevalence ...
  • Phytochemical screening and antibacterial activity of Cyclamen persicum Mill tuber extracts 
    Raed Alkowni, Shehdeh Jodeh; Fatima Hussein, Nidal Jaradat (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    The emerging drug resistance bacteria increased the demand on the discovery of antibiotics from natural sources. This research was aimed to study the antibacterial reactivity; as well as the phytochemicals, of the wild ...
  • Effects of gamma irradiation on the physico-chemical and biological properties of levofloxacin 
    Saleem Raza; Yousaf Iqbal; Ihsan Ullah; Mubarak, Mohammad S; Hameed, Muhammad Usman; Muslim Raza (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    The aim of the present study was to examine the effect of gamma radiation on levofloxacin. Powder form of levofloxacin was subjected to different radiation doses (25, 50, 75, 100 and 125kGy) of Cobalt-60 source in ...
  • Analgesic and anti-inflammatory activities of the ethanol extract of Hibiscus rosa sinensis Linn (roots) 
    Zubia Begum; Ishrat Younus; Khan, Husna (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-09-23)
    The current study aimed to evaluate the analgesic and anti-inflammatory effects of the ethanolic extract of roots of Hibiscus rosa sinensis (HRS). The ethanolic extract was studied on tail flick test, acetic acid induced ...
  • Spectrophotometric analysis of some metals and phytochemical screening of Digera muricata (Leaves and stems) 
    Isam Eldin Hussein Elgailani (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-09-21)
    The current research deals with estimation of the spectrophotometric analysis of some metals and phytochemical screening of the plant Digera muricata. The importance plant study arises from the fact that it has both ...
  • Rapid diagnostic method of tobacco products in saliva by fourier transform infrared spectroscopy (FTIR) 
    Channa, Naseem Aslam; Kalhoro, Dost Muhammad; Jahangir, Taj Muhammad (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    The present study was designed to explore the easy and fast method diagnosis of tobacco products in saliva of tobacco users (TU) by FTIR. Sixty four male tobacco users (TU) with mean age range 15.3 to 30.7 years were ...
  • Antileishmanial, insecticidal and phytotoxic potential of leaves and stems of Rumex nervosus Vahl. 
    Khan, Rasool; Mohammed Mansour Quradha; Abdullah Qasem Saif; Jawad Ali; Abdur Rauf (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-09-20)
    Biological assays including; phytotoxicity, brine shrimp lethality, antileishmanial and insecticidal activities were carried out on crude methanolic extracts of stems and leaves of R. nervosus and their fraction namely; ...
  • Spray-dried curcumin nanoemulsion: A new road to improvement of oral bioavailability of curcumin 
    Liandong Hu; Qiaofeng Hu; Chenchen Yang (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    In this study a new soluble solid curcumin nanoemulsion powder was prepared using spray-drying technology to improve the solubility and bioavailability of curcumin. The liquid nanoemulsion consisted of curcumin, Capryol ...
  • Safety of fenbendazole in common peafowl (Pavo cristatus) 
    Seema Abbas Sajid Umar; Khan, Muhammad Irfan; Qamar-un-Nisa; Muhammad Younus; Kiran Aqil; Rizwan Qayyum; Muhammad Yaqoob; Asif Ali; Yaseen, Muhammad Asif; Shah, Muhammad Ali (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    The present study was undertaken to find out the safety levels of fenbendazole in common peafowl. This bird, raised on aviaries and zoos, can be severely parasitized with Ascaridia galli (enteric worms) and Syngamus trachea ...
  • Pharmacological and phytochemical analysis of Bergenia ciliata leaf and rhizome extracts 
    Saiqa Yousaf; Ghazala Kaukab; Hina Gul; Nauman Khalid; Rehana Kausar; Haroon Ahmed; Huma Ajab; Muhammad Gulfraz (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-09-19)
    Antibacterial, antifungal, antioxidant, cytotoxic, and anti-haemolytic activity of various rhizome extracts of Bergenia ciliata were evaluated in this study. The results showed inhibition of the growth of all selected ...
  • A novel spectrophotometric determination of caroverine in pharmaceutical formulations via derivatization with Folin-ciocalteu Phenol reagent 
    Asad Raza; Ansari, Tariq Mahmood (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    In this study we have reported a new, fast and extraction free spectrophotometric procedure for the assessment of caroverine in pharmaceutical raw and tablet dosage forms. In the reported visible spectrophotometric procedure ...
  • Development and evaluation of mucoadhesive buccal tablet containing metronidazole for the treatment of periodontitis and gingivitis 
    Sobia Razzaq; Sana Hanif; Muhammad Ali Syed; Javed Iqbal; Syed Saeed ul Hassan; Syed Atif Raza; Humayun Riaz; Farah Abid (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-09-18)
    The current study was designed to evaluate mucoadhesive buccal tablet containing metronidazole (MTZ) for local action aided by Hydroxypropylmethylcellulose K4M (HPMC) and Carbopol 940® (CP) as mucoadhesive polymers with ...
  • Comparison of atherogenic index and lipid profiles in candidates for coronary artery bypass graft surgery versus normal people 
    Mahmood Hosseinzadeh Maleki; Maryam Mousavi; Toba Kazemi; Nahid Azdaki; Amir Rahmanian Sharifabad; Hoshyar, Reyhane (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-09-17)
    Information on incidence and risk factors of cardiovascular disease (CVD) is rare in the Middle East. This study aims to compare Iranian candidates for coronary artery bypass graft (CABG) surgery and healthy controls in ...
  • Antiulcer activity of methanol-chloroform extract of Channa striatus fillet 
    Azemi, Ahmad Khusairi; Abd Rahim, Mohd Hafiz; Mamat, Siti Syariah; Mat Jais, Abdul Manan; Zakaria, Zainul Amiruddin (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    Channa striatus (Haruan) is Malaysian freshwater fish that is traditionally used to treat ailments related to wound and also ulcers. The aimed of the present study was to determine the mechanisms of anti-ulcer activity of ...

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