Metformin is one of the most common medicines for the treatment of type 2 diabetes, however, recent studies suggest that concomitant antihyperglycemic agents should be administered for better efficacy. Yukmijihwang-tang (YMJHT) ...

In this paper, we investigated the effects of protein from sea buckthorn seed on the expression of genes involved in liver glucose metabolism and on the activation of the AMPK/SIRT1 pathway in streptozotocin (STZ)- induced ...

This study was to investigate the effect of methotrexate in combination therapy by the characteristic cytokine in Th17 cells and the frequency of Tregs, which involved in the induction and pathological progress of ...

Imposex is a genital disorder characterized by imposition of male sexual characteristics in female gastropods due to exposure to tributyltin (TBT). TBT is used as biocidal agent in antifouling paints, applied on the ship ...

The aim of this study was to design and develop controlled porosity osmotic pumps containing glibenclamide (as an insoluble agent) coated with nano-scale pore formers. Solubility enhancement methods including co-grinding ...

The occurrence rate of senile dementia among diabetes patients is high, but there is still no effective therapeutic method. This study aimed to explore curative effect of exosomes deriving from MSCs treating diabetesinduced ...

The caryopses (seeds) of Echinochloa colona Link of family Poaceae are traditionally used for the treatment of jaundice. The methanolic extract of caryopses of Echinochloa colona (ECME) was evaluated for its hepatoprote ...

Geniposide and baicalin, the main components of Huangqin-Zhizi herb pair, have been combined to increase the efficacy. To reveal the underlying compatibility mechanism of these two components, the synergistic effects ...

Inflammation is an aggregate of different pathologic responses in body that leads to life threatening conditions if not combated at early stages. A variety of chemical medications from low quality to high quality are ...