Abstract:
To explore the relationship between the clinical manifestations and functional magnetic resonance images
(MRI) of delayed encephalopathy after carbon monoxide intoxication. Six patients received the MRI were diagnosed
with delayed encephalopathy after carbon monoxide (CO) poisoning. Clinical manifestations were observed in each
patient. MRI revealed multiple lesions. The majority of the lesions were located in the globus pallidus, sub cortical white
matter, and basal ganglia. The cognitive injury, akinetic mutism, fecal and uroclepsia, forced crying, forced laughing and
extra pyramidal syndromes such as chorea and parkinsonism were manifested in clinic. Cognitive impairment improved
greatly while involuntary movements only improved slightly after several months. Meanwhile brain MRI suggested
remarkable improvement. Neuroimaging directly correlated with the clinical manifestations