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Browsing 2006,Part-1 by Issue Date

Browsing 2006,Part-1 by Issue Date

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  • RESEARCH PROJECTS Vol-II 
    Unknown author (Pakistan Science Foundation, 1990)
  • EFFECT OF PROCESSING VARIABLES ON MICRO PARTICULATE SYSTEM OF ACECLOFENAC 
    DASHORA, KAMLESH; SARAF, S; SARAF, SWARNLATA (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2006-01-02)
    Microparticulate systems of aceclofenac were prepared by modified solvent evaporation method using different variables such as polymer (cellulose acetate): drug ratios (1:9, 1:6, 1:3, and 1:1), agitation speeds (500-1500 ...
  • RELATIONSHIP OF BRAIN TRYPTOPHAN AND SEROTONIN IN IMPROVING COGNITIVE PERFORMANCE IN RATS 
    KHALIQ, SAIMA; HAIDER, SAIDA; P. AHMED, SHAHIDA; PERVEEN, TAHIRA; J. HALEEM, DARAKHSHAN (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2006-01-03)
    Brain function can be affected by the availability of dietary precursors of neurotransmitters. The diet induced increase in tryptophan (TRP) availability has been shown to increase brain serotonin synthesis and various ...
  • INTERACTIONS BETWEEN SPARFLOXACIN AND ANTACIDS – DISSOLUTION AND ADSORPTION STUDIES 
    HUSSAIN, FIDA; ARAYNE, M. SAEED; SULTANA, NAJMA (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2006-01-04)
    Sparfloxacin is a broad-spectrum oral fluoroquinolone antimicrobial agent with a long elimination half-life, extensively used against both Gram-positive as well as Gram-negative microorganism. Concurrent administration ...
  • MODIFICATION OF DRUG RELEASE FROM ACETAMINOPHEN GRANULES BY MELT GRANULATION TECHNIQUE – CONSIDERATION OF RELEASE KINETICS 
    UHUMWANGHO, M.U.; OKOR, R.S. (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2006-01-05)
    Acetaminophen granules have been formed by a melt granulation process with the objective of retarding drug release for prolonged action formulations. The waxes used were goat wax, carnuba wax and glyceryl monostearate. ...
  • IN VITRO AVAILABILITY OF METFORMIN IN PRESENCE OF H2 RECEPTOR ANTAGONISTS 
    SULTANA, NAJMA; SAEED ARAYNE, M.; AHMED, NOMAN (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2006-01-06)
    Metformin is a guanidine derivative used for the treatment of NIDDM. As it is used for a long-term therapy, it may be coadministered with other drugs. Present paper deals with the in vitro availability studies of metformin ...
  • REACTIONS OF PHTHALIMIDES WITH 1-METHYLETHYLAMINE: ANALGESIC AND ANTI-INFLAMMATORY PROPERTIES OF RESULTING CARBOXAMIDES 
    OKUNROBO, L. O.; USIFOH, C. O.; OKPO, S. O. (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2006-01-07)
    The reaction of phthalimide derivatives (1a-c) with 1-methylethylamine in dimethylformamide (DMF) at room temperature afforded benzamido-N-prop-2-ynyl-2-(2-methylethyl)-carboxamide (3a), benzamido-N-cyclopentyl-2- ...
  • A RP-HPLC METHOD FOR THE ASSAY OF CEFPIROME AND ITS APPLICATION IN DRUG-METAL INTERACTION STUDIES 
    ARAYNE, M. SAEED; SULTANA, NAJMA; NAWAZ, M (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2006-01-08)
    An accurate, sensitive and least time consuming RP-HPLC method for the estimation of cefpirome in the presence of essential and trace metal has been developed and validated. Cefpirome was eluted from a B144A, OD-5-100, C18 ...
  • DETERMINATION OF THE ASCORBIC ACID CONTENT OF TWO MEDICINAL PLANTS IN NIGERIA 
    H.A, OKERI; P.O, ALONGE (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2006-01-09)
    The fresh and dried leaves of two edible plants, Oldenlandia corymbosa and Dissotis rotundifolia have been assayed for their ascorbic acid content. They were found to be rich sources of ascorbic acid (vitamin C) when ...
  • THE EFFECTS OF MEFENAMIC ACID ON HEMATOCRIT OF THE LIZARD, UROMASTIX HARDWICKII 
    AHMAD, MAHMOOD; AHMAD, MANSOOR; HASAN, RUQAIYA; QURESHI, ANILA; AHMED, ZULFIQAR (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2006-01-10)
    Mefenamic acid is an analgesic, antipyretic and anti-inflammatory agent. In addition induces several hematological disturbances. Present study was conducted to determine the alterations in blood PCV of the lizard Uromastix ...
  • PAEDIATRIC NOSOCOMIAL INFECTIONS: RESISTANCE PATTERN OF CLINICAL ISOLATES 
    NAEEM M, IYAD; NAQVI, BAQIR S; HASHMI, KHURSHEED; GAUHAR, SHAHNAZ (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2006-01-11)
    Hospital acquired infections are transmitted to patients by hospital personnel and other patients, or they may arise from patient’s own endogenous flora. Children are one of the most susceptible subjects associated in the ...
  • CHEMICAL COMPOSITION OF EGYPTIAN AND UAE PROPOLIS 
    A. SAID, SOBHI; A. KHAN, SAEED; AHMAD, IQBAL; S. ALI, HAYAM (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2006-01-12)
    The chemical composition of propolis samples obtained from Behera, Egypt and Dubai, UAE, have been investigated by GC-MS and thirty four compounds have been tentatively identified. Some of these compounds have not been ...
  • OBESITY: AN INDEPENDENT RISK FACTOR FOR SYSTEMIC OXIDATIVE STRESS 
    IQBAL KHAN, NAZISH; NAZ, LUBNA; YASMEEN, GHAZALA (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2006-01-13)
    The role of obesity in diabetes mellitus, hyperlipidemia, colon cancer, sudden death and other cardiovascular diseases has confirmed in many recent research studies. In present study, it is hypothesized that obesity can ...
  • PATIENT COUNSELING BY PHARMACIST -A FOCUS ON CHRONIC ILLNESS 
    PALAIAN, SUBISH; PRABHU, MUKHYAPRANA; SHANKAR, P. RAVI (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2006-01-14)
    The management of chronic illness needs lifestyle modifications and drug therapy for a long period. Patient understanding regarding the illness plays a very important role in management of chronic illness. Effective patient ...
  • FABRICATION OF NANOPARTICLES WITHIN POLYMERIC PORES FOR CONTROLLED RELEASE OF DRUG 
    ASIF, MUHAMMAD; ARAYNE, M. SAEED; SULTANA, NAJMA; HUSSAIN, FIDA (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2006-01-15)
    Nanotechnology, a multidisciplinary scientific undertaking, involves creation and utilization of materials, devices or systems on the nanometer scale. The field has enabled the development of an amazing variety of methods ...
  • SIMULTANEOUS ESTIMATION OF ATORVASTATIN AND RAMIPRIL BY RP-HPLC AND SPECTROSCOPY 
    JOSEPH, LINCY; GEORGE, MATHEW; RANGA RAO B, VENKATA (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2008-07-13)
    A number of analytical methods were reported for the estimation of atorvastatin and ramipril from their individual dosage forms or in combination with other drugs (Valiyare, 2004; Vachareau and Neirinck, 2000). Here ...
  • PERIPHERAL INJECTION OF DEXAMETHASONE MODULATES ANXIETY RELATED BEHAVIORS IN MICE: AN INTERACTION WITH OPIOIDERGIC NEURONS 
    ALI VAFAEI, ABBAS; RASHIDY-POUR, ALI; ALI TAHERIAN, ABBAS (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2008-07-14)
    Stress and anxiety initiates a cascade of biochemical and endocrine event which results in behavioral and electrophysiological effects in both animals and humans. In this study, we investigated the effects of dexamethasone ...
  • NASAL CARRIAGE OF STAPHYLOCOCCI IN HEALTH CARE WORKERS: ANTIMICROBIAL SUSCEPTIBILITY PROFILE 
    FARZANA, KALSOOM; RASHID, ZERMINA; AKHTAR, NAVEED; SATTAR, ABDUL; ALI KHAN, JAMSHAID; NASIR, BUSHRA (Karachi: Pakistan Journal of Botany, Botanical Garden, University of Karachi, 2008-07-15)
    One year prospective study was evaluated to ascertain the prevalence of nasal carriage of potentially pathogenic bacteria in health care workers and the antibiotic susceptibility profile. The bacterial strains were identified ...
  • ANTI-INFLAMMATORY ACTIVITY OF INDANYLTETRAZOLE DERIVATIVES 
    BEPARY, SUKUMAR; DAS, BIPLAB K; C. BACHAR, SITESH; K. KUNDU, JOYDEV; SHARA SHAMSUR ROUF, ABU; K. DATTA, BIDYUT (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2008-07-16)
    A number of indanyl tetrazolederivatives namely 5-(6′-chloroindan-1′-yl)tetrazole (CIT), 5-(6′-bromoindan1′-yl)tetrazole (BIT), 5-(6′-chloroindan-1′-yl)methyltetrazole (CIMT), 5-(6′-bromoindan-1′-yl)methyltetrazole (BIMT) ...
  • ASSESSMENT OF BIOEQUIVALENCE OF CIPROFLOXACIN IN HEALTHY MALE SUBJECTS USING HPLC 
    KHALID KHAN, MUHAMMAD; FARID KHAN, MUHAMMAD (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2008-07-17)
    Pharmacokinetics and bioequivalence studies of two brands of ciprofloxacin 500mg (Ciprofloxacin & Ciproxin) were evaluated in 14 healthy male volunteers after oral administration. The drug was analyzed in plasma samples ...

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