dc.contributor.author |
Lateef, Mehreen |
|
dc.contributor.author |
Farheen, Sadia |
|
dc.contributor.author |
Naqvi, Beena |
|
dc.contributor.author |
Iqbal, Lubna |
|
dc.contributor.author |
Siddiqui, Kauser |
|
dc.date.accessioned |
2022-10-12T03:42:55Z |
|
dc.date.available |
2022-10-12T03:42:55Z |
|
dc.date.issued |
2020-05-17 |
|
dc.identifier.citation |
Lateef, M., Farheen, S., Naqvi, B., Iqbal, L., & Siddiqui, K. (2020). Native wild plants in Karachi, Pakistan: Rich source of antioxidant raw material. Pakistan Journal of Pharmaceutical Sciences, 33(3). |
en_US |
dc.identifier.issn |
1011-601X |
|
dc.identifier.uri |
http://142.54.178.187:9060/xmlui/handle/123456789/12970 |
|
dc.description.abstract |
Extracts of nine plants were studied for DPPH radical scavenging and reducing abilities. Pentatropis spiralis, Calotropis procera, Helitropium curassavicum, Withania somnifera and Chenopodium album showed reducing power ranging from 34% to 146%. Suaeda fruticosa, Trianthema portulacastrum, Pluchea lanceolata and Rumex dentatus has excellent antioxidant potential proved by their DPPH scavenging and reducing power. 1000µg/10µl chloroform extract of S. fruticosa gave 92% scavenging with IC50 value less than 0.7µg/10µl while its hexane extract possessed 80% reducing activity at 100µg/10µl concentration. DPPH free radical scavenging by methanolic extract of Trianthema portulacastrum was 60% and 76% at 1000 and 100µg/10µl respectively with IC50 value of 0.03µg/10µl while the reducing activity of 124% at 100µg/10µl. Methanolic extract of P. lanceolata showed 91% and 70% scavenging activity at 1000 and 100µg/10µl with IC50 value of 0.7µg/ 10µl. Reducing power is comparable with the reference BHA standard that is 98% at 100µg/10µl concentration. Rumex dentatus’ extracts are excellent DPPH scavengers and hydrogen donators produced 156% reduction. Chloroform extract was inefficient antioxidant. These results make these plants a candidate for future research for treating ailments due to imbalance in free radicals. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi. |
en_US |
dc.subject |
Antioxidant activity |
en_US |
dc.subject |
DPPH free radical scavenging |
en_US |
dc.subject |
reducing power |
en_US |
dc.subject |
wild plants |
en_US |
dc.title |
Native wild plants in Karachi, Pakistan: Rich source of antioxidant raw material |
en_US |
dc.type |
Article |
en_US |