dc.identifier.citation |
Anum, F., Aftab, A., Tahir, A., Khalid, A., Yousaf, Z., Aftab, Z. H., ... & Raza, S. (2019). PHYTOCHEMICAL ANALYSIS AND ANTIFUNGAL POTENTIAL EVALUATION OF Phyllanthus emblica. Pakistan Journal of Science, 71(2), 89. |
en_US |
dc.description.abstract |
The Present research work was conducted to examine phytochemical analysis and
antifungal activity of Phyllanthus emblica. Extraction was performed through maceration method
using different solvents and analyzed for the occurrence of secondary metabolites. Positive results
were obtained for Saponins, Tannins, Falvonoids and Cardiac glycosides whereas negative results
observed for Alkaloids, Anthraquinones and Phlobotanins. Antioxidant activity of plant extracts was
also checked which showed strong results for Antioxidant activity as compared to commercially
available standard antioxidants. In total antioxidant assay methanol extract of plant possesses high
antioxidant potential showing the value 0.44 ± 0.134a which was closer to the standard BHT (Standard)
0.479 ± 0.24a
. In case of DPPH assay chloroform extract value (0.213 ± 0.041) was found closer to
BHT (Standard) when compared, whose value is 0.190 Antifungal activity of plant was carried out
against fungal strains (Botrytis cinerea and Aspergilus niger), zones of inhibition were measured and
compared with the commercially available standard antifungal discs (Itraconazole and Fluconazole).
The highest value against B. cinerea was observed for chloroform extracts 20.83 nm, whereas in case
of A. niger distilled water showed maximum value of 16.5 nm. Based on the results obtained in the
present study, Phyllanthus emblica fruits are rich in phytochemical constituents and possess potent
antifungal activity against pathogenic fungi and can be used in treating various diseases caused by
these fungal species. |
en_US |