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Vicissitudes in polyphenolic extract-based high internal phase creams (HIPCs)- effect of storage temperature dependent characteristics

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dc.contributor.author Ali, Atif
dc.contributor.author Akhtar, Naveed
dc.contributor.author Khan, Hira
dc.contributor.author Adnan Jamil, Qazi
dc.contributor.author Hussain Shah, Sajid
dc.contributor.author Naeem, Muhammad
dc.contributor.author Hassham Hassan Bin Asad, Muhammad
dc.date.accessioned 2022-10-18T10:41:00Z
dc.date.available 2022-10-18T10:41:00Z
dc.date.issued 2020-11-07
dc.identifier.citation Ali, A., Akhtar, N., Khan, H., Jamil, Q. A., Shah, S. H., Naeem, M., & Asad, M. H. H. B. (2020). Vicissitudes in polyphenolic extract-based high internal phase creams (HIPCs)-effect of storage temperature dependent characteristics. Pakistan Journal of Pharmaceutical Sciences, 33(6), 2521-2527. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/13224
dc.description.abstract The purpose of this investigation was to evaluate the vicissitudes in polyphenolic extract- based high internal phase creams (HIPCs) and effect of storage temperature dependent characteristics. Rheological parameters, that is, power law and IPC analysis with its physical characteristics were exploredat different storage temperatures (8°, 25°, 40° and 40° with 75% relative humidity- RH) with different time intervals up to 2 months of newly formulated poly-phenolic extract- based high internal phase cream and its comparison with base. Polyphenolic- based HIPCs showed nonNewtonian- pseudo plastic tendencies in vicissitudes with time and storage temperatures. Data analysis with Power Law and IPC paste was found to fit to all the rheograms. Flow index, shear sensitivity factor, consistency Index and 10 RPM of freshly prepared HIPCs with and without encapsulated polyphenolic extract were found to be 0.5,0.53, 386.4 cP, and 432.9 cP, respectively.The viscosities were fallen with rise in shear stress.There was no change in color, electrical conductivity, liquefaction and phase separation after centrifugation in any sample of polyphenolic extract– based HIPCs and its base. Polyphenolic- based extract HIPCs behaved non-Newtonian- pseudo plastic tendencies and showed stability up to 2 months and can be directed absolutely to shield skin against ultraviolet radiation (UV) intervened oxidative mutilation. en_US
dc.language.iso en en_US
dc.publisher Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi. en_US
dc.subject Formulation en_US
dc.subject rheology en_US
dc.subject storage temperature en_US
dc.subject high internal phase creams en_US
dc.title Vicissitudes in polyphenolic extract-based high internal phase creams (HIPCs)- effect of storage temperature dependent characteristics en_US
dc.type Article en_US


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