Abstract:
Corona Virus (COVID-19) outbreak has threatened the world, since it has become pandemic and spread all
over the world. The causative agent SARS-COV2 has proved lethal caused serious public health concern worldwide.
Our aims were to describe the SARS-COV-2 genetic connections and check for recombination of all genome. The
recombination was investigated by RDP5 and conflicting phylogenetic clustering in individual genomic fragments was
established by phylogenetic study by maximum likelihood and Bayesian methods. Our analysis suggests that the
available sequences from currently genomes of various strain were retrieved from different countries including Japan,
French Republic, Spain, Peru, China, Vietnam, Taiwan, Brazil, U.S.A., South Korea, Sweden, Australia, Nepal, India,
Iran, and Italy. The phylogeny of SARS-COV-2 observed the largest number of genome is Vietnam 29891-bp, while
France is the smallest member identified with 29679-bp. Using Recombination Detection program5 (RDP5) the china
strains was taken as parental strain but there were no recombination in the all strains. In our study we identified the
mutation in Pakistani strains in high conserved region of Corona nucleoca super family domain at the nucleotide position
(394: C replace with T, Position: 858: C replace with T and Position: 997 G replace A).
