Abstract:
In this research study very first time a herbal ointment contain 10% Salvadora persica extract was compared
with Solcosseryl jelly 10% and blank Vaseline to evaluate wound healing effects using excision wound healing model in
animals. Three groups of rats (n-6) were experimentally wounded on the back of their neck. Group I was dressed with
Vaseline containing 10% test drug, Group II was treated with thin layer of Solcoseryl jelly 10% as reference drug while
Group III was dressed with thin layer of blank Vaseline as control group. The effect of vehicle on rate of wound healing
were assessed and in all cases there were progressive decreased in wound area with time but wound dress with Vaseline
containing S. persica extract and wound treated with Solcosseryl jelly significantly healed earlier than those treated with
Vaseline. It is concluded that S. persica extract significantly enhance the acceleration rate of wound enclosure in rats.
