Abstract:
In the present study, we synthesized silver (Ag) nanoparticles using aqueous extracts of clove (Syzygium
aromaticum) (SAE). This synthesis of green silver nanoparticles (AgNP) was a novel and effectual tool against the
Newcastle Viral Disease (NDV). Syzygium aromaticum extract was used as reducing and stabilizing agent for synthesis
of silver nanoparticles. AgNP were characterized using diversity of biophysical methods inclusive of Fourier transform
infrared spectroscopy (FTIR), UV-VIS spectroscopy and Transmission electron microscopy (TEM) for morphology and
size. Furthermore, XRD analysis confirmed the crystalline nature of the particles. In current investigations, the antiviral
activity of clove buds silver nanoparticles was inspected in-vitro and in-ovo. Embryonated chicken eggs were used to
perform the cytotoxicity assay of the clove extract silver nanoparticles (CESN). CESN showed in vitro antiviral activity
against NDV in embryonated eggs.
