Abstract:
Drug utilization evaluation (DUE) is an arrangement of continuous, orderly, criteria-based assessment of
medication utilizes to guarantee that medicines are utilized suitably. In the event that treatment is regarded to be
improper, provider and patient intervention may be important to optimize therapeutic efficacy. In the present study drug
utilization evaluation of Piperacillin/Tazobactam was carried out in prospective manner. A well structured data
collection form was constructed to collect the related information regarding demographic, clinical use, indication, culture
sensitivity criteria, outcomes of therapy, renal impairment cases of dose adjustments and appropriate use. Results of chi
square indicated insignificant relationship between gender and as p value was found to be p=0.446 and 0.111 for use of
drug alone and in combination. Similarly insignificant relationship between gender and use of drug in combination with
other antibiotics as p value was found to be p=0.111. It was found that from 61-70 years (Therapeutic Effectiveness;
n=12, 9.37%), (Therapeutic Failure; n=10, 45.45%) and mortality (n=1, 50%) were quite higher. The prescription pattern
was in accordance with standard guidelines. Study indicated need to elevate prescribers to pursue generic prescribing and
rationally utilize antibiotics to avert advancement of resistance at the level of hospital and community. These sorts of
studies are valuable for acquiring data about medication utilize designs and for recognizing inconceivable expense of
medicines.
