Abstract:
Thyroid dysfunction is an important factor to cause failure in assisted reproduction technology (ART)
procedures. In this study, we recorded the serum level of thyroid autoantibody to fig. out its relationship with the ART
outcome. The results showed that the serum concentrations of TSH had a statistically significant increase between the
basal level and the levels at time of serum pregnancy test both in women with and without thyroid autoantibody (p=
0.002 and p=0.019, respectively). Additionally, the TSH level increased significantly in thyroid autoantibody-positive
group than those in thyroid autoantibody-negative group during controlled ovarian hyper stimulation (COH) process(p =
0.006). The risk of preterm delivery was lower in thyroid autoantibody-negative group. In sum, the present study
provided evidence of an association between thyroid autoantibody and preterm delivery in euthyroid women.
