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The effect of thyroid autoantibody on assisted reproduction technology outcome in euthyroid women: One center experience

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dc.contributor.author Zhuang, Lili
dc.contributor.author Liu, Xiaoyan
dc.contributor.author Cong, Jianxiang
dc.contributor.author Zhang, Ning
dc.contributor.author Qu, Qinglan
dc.contributor.author Hao, Cuifang
dc.date.accessioned 2022-10-20T09:45:13Z
dc.date.available 2022-10-20T09:45:13Z
dc.date.issued 2021-01-16
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/13396
dc.description.abstract Thyroid dysfunction is an important factor to cause failure in assisted reproduction technology (ART) procedures. In this study, we recorded the serum level of thyroid autoantibody to fig. out its relationship with the ART outcome. The results showed that the serum concentrations of TSH had a statistically significant increase between the basal level and the levels at time of serum pregnancy test both in women with and without thyroid autoantibody (p= 0.002 and p=0.019, respectively). Additionally, the TSH level increased significantly in thyroid autoantibody-positive group than those in thyroid autoantibody-negative group during controlled ovarian hyper stimulation (COH) process(p = 0.006). The risk of preterm delivery was lower in thyroid autoantibody-negative group. In sum, the present study provided evidence of an association between thyroid autoantibody and preterm delivery in euthyroid women. en_US
dc.language.iso en en_US
dc.publisher Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi en_US
dc.subject Thyroid stimulating hormone (TSH) en_US
dc.subject thyroid auto-antibodies en_US
dc.subject controlled ovarian hyper stimulation en_US
dc.subject assisted reproductive en_US
dc.subject technology en_US
dc.title The effect of thyroid autoantibody on assisted reproduction technology outcome in euthyroid women: One center experience en_US
dc.type Article en_US


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