Abstract:
The present research study investigates the phytochemical and pharmacological importance of Bromus
pectinatus. Qualitative phytochemical analysis of this plant was carried out to use standard method for the presence of
various bioactive constituents. Results showed the ethanolic extract contain natural product such as steroids, alkaloids,
tannins, coumarin, saponins, flavonoids and phenols. These compounds play a key role to reducing various disease and
microbial inhibition. The ethanolic extract also showed the antimicrobial and antifugal activity against different
pathogenic bacterial strains e.g Escherichia coli, Micrococus leutus, Protus vulgarus, and Kelebsela pneumona and three
fungal strains Aspergillus fumigatus, Aspergillus flavous, Aspergillus niger. The antioxidant assay was performed as %
inhibition of DPPH (1, 1-diphenyl-2-picryl-hydrazyl) free radicals. The plant extract has more antioxidant activity as
compared to ascorbic acid. The maximum concentration (800µg/ml) is the most effective of all. The plant extract showed
the high cytotoxicity activity against Brine shrimp. Moreover, the plant extract exhibited allelopathic effect on different
growth parameters of wheat plant mostly at higher concentration. These results indicate that the BPEE have a potential
broad-spectrum antimicrobial, cytotoxic, antioxidant and phytotoxic activity due to the presence of bioactive compounds.
