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Phytochemical screening and biological activities of Bromus pectinatus Thunb

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dc.contributor.author Begum, Kausar
dc.contributor.author Abbas, Saira
dc.contributor.author Mushtaq, Nadia
dc.contributor.author Khan, Saad Ullah
dc.contributor.author Parveen, Ishrat
dc.contributor.author Jamil ur Rahman, H.
dc.contributor.author Mahmood, Sultan
dc.date.accessioned 2022-10-20T09:57:31Z
dc.date.available 2022-10-20T09:57:31Z
dc.date.issued 2021-01-16
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/13435
dc.description.abstract The present research study investigates the phytochemical and pharmacological importance of Bromus pectinatus. Qualitative phytochemical analysis of this plant was carried out to use standard method for the presence of various bioactive constituents. Results showed the ethanolic extract contain natural product such as steroids, alkaloids, tannins, coumarin, saponins, flavonoids and phenols. These compounds play a key role to reducing various disease and microbial inhibition. The ethanolic extract also showed the antimicrobial and antifugal activity against different pathogenic bacterial strains e.g Escherichia coli, Micrococus leutus, Protus vulgarus, and Kelebsela pneumona and three fungal strains Aspergillus fumigatus, Aspergillus flavous, Aspergillus niger. The antioxidant assay was performed as % inhibition of DPPH (1, 1-diphenyl-2-picryl-hydrazyl) free radicals. The plant extract has more antioxidant activity as compared to ascorbic acid. The maximum concentration (800µg/ml) is the most effective of all. The plant extract showed the high cytotoxicity activity against Brine shrimp. Moreover, the plant extract exhibited allelopathic effect on different growth parameters of wheat plant mostly at higher concentration. These results indicate that the BPEE have a potential broad-spectrum antimicrobial, cytotoxic, antioxidant and phytotoxic activity due to the presence of bioactive compounds. en_US
dc.language.iso en en_US
dc.publisher Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi en_US
dc.subject Bromus pectinatus en_US
dc.subject medicinal plant en_US
dc.subject antimicrobial activity en_US
dc.subject phytochemical screening en_US
dc.subject phytochemical screening en_US
dc.title Phytochemical screening and biological activities of Bromus pectinatus Thunb en_US
dc.type Article en_US


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