Abstract:
Background: Malignant lesions of the cervix represent the most frequent cause of mortality and morbidity in
females and a common cause of cancer deaths worldwide. In Pakistan, the frequency of uterine and cervical
neoplasms is increasing in the past few decades.
Aims: This retrospective study was conducted in AMDC to evaluate the importance of conventional Papanicolaou
(Pap) smears in diagnosing the premalignant lesions of the cervix. Materials and Methods: The Pap smears of the female patients aged between 18 to 78 years received at AMDC during the period of five years were included. i.e. from January 2012 to June 2017.
Results: In our study, the frequency of benign and premalignant/malignant lesions was found to be 94% and 3.4% respectively. The neoplastic lesion reported were 6, among these lesion were low-grade squamous cell
intraepithelial lesions (LSILs) (2, 33%),atypical squamous cells of undetermined significance (ASCUS) (3, 50%) and high-grade squamous cell intraepithelial lesions (HSILs) (1, 16%).
Conclusion: The cytopathological examination of papanicolaouis smear of the cervix is well suited for diagnosing benign and neoplastic lesions of cervix.