Abstract:
Medicinal and aromatic plants contribute to major portion of the flora. The plant materials obtained from these
plants are used in the pharmaceuticals, cosmetics, and drug industries. Tamarix dioica is locally used in the management
of splenic and hepatic inflammation as well as diuretic and carminative. It also possesses cytotoxic, antimicrobial,
antifungal and anti-inflammatory activity. The present study investigates the anti-inflammatory, anti-pyretic and
analgesic activities of the crude methanolic extract from Tamarix dioica. Anti-inflammatory activity was measured by
Carrageenan Induced Paw Edema and Xylene Induced Ear Edema methods. Pyrexia induction with Brewer’s yeast assay
was used to determine antipyretic activity and analgesic activity was estimated by acetic acid induced writhing and hot
plate methods. The data indicated that anti-inflammatory, anti-pyretic and analgesic activities of the crude methanolic
extract from Tamarix dioica was dose and time dependent when measured by different assays. Exposure of model animal
to increasing concentrations of the plant extract for longer period increased their anti-inflammatory, anti-pyretic and
analgesic activities. Significantly highest anti-inflammatory, anti-pyretic and analgesic activities were noted at highest
doses of the crude methanolic extract for longer exposure compared with their respective controls.
