PASTIC Dspace Repository

The mouse model of hepatic veno-occlusive disease

Show simple item record

dc.contributor.author An, Licai
dc.contributor.author Li, Xijing
dc.contributor.author Chu, Xiaoxia
dc.contributor.author Liu, Xiaoqian
dc.contributor.author Zhang, Yuanfeng
dc.contributor.author Wang, Yanming
dc.contributor.author Wang, Yan
dc.contributor.author Liu, Yinghui
dc.date.accessioned 2022-10-27T10:46:40Z
dc.date.available 2022-10-27T10:46:40Z
dc.date.issued 2021-11-02
dc.identifier.citation An, L., Chu, X., Liu, X., Zhang, Y., Wang, Y., & Liu, Y. (2021). The mouse model of hepatic veno-occlusive disease. Pakistan Journal of Pharmaceutical Sciences, 34(6 (Special)), 2391-2400. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/13818
dc.description.abstract With the application of hematopoietic stem cell transplantation, Subacute or acute increase in the incidence of hepatic veno-occlusive disease (HVOD) becomes more common and it can lead to fatal complications. This article characterizes a mouse model of HVOD induced by monocrotaline. After gavage with monocrotaline was performed on BALB/c mice, On the 3rd, 4th, 6th, 8th and 10th days, mice were anesthetized, blood was collected and the liver was removed. Liver slices were processed by HE stain, Masson’s trichrome stain or immunohistochemical stain. From days 3 through 4, histopathology and cytokine changes were determined as severe, early HVOD. From days 6 through 8, the changes were considered to represent late HVOD. On the 10th day, the above changes showed that late HVOD gradually improved. en_US
dc.language.iso en en_US
dc.publisher Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi. en_US
dc.subject Animal model en_US
dc.subject endothelial cell en_US
dc.subject fibrosis en_US
dc.subject inflammatory cytokines en_US
dc.subject liver function en_US
dc.title The mouse model of hepatic veno-occlusive disease en_US
dc.type Article en_US


Files in this item

This item appears in the following Collection(s)

Show simple item record

Search DSpace


Advanced Search

Browse

My Account