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Effects of sodium hyaluronate combined with rhEGF eye drops in patients with dry eye

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dc.contributor.author Ren, Weina
dc.contributor.author Chen, Tingting
dc.contributor.author Dong, Wenpeng
dc.contributor.author Tong, Qihu
dc.date.accessioned 2022-10-28T07:57:17Z
dc.date.available 2022-10-28T07:57:17Z
dc.date.issued 2021-11-12
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/13843
dc.description.abstract To analyze the effects of sodium hyaluronate combined with recombinant human epidermal growth factor (rhEGF) eye drops in patients with dry eye. Totally 97 patients who suffered dry eye after cataract surgery in our hospital from March 2018 to June 2020 were selected and randomly assigned into control group (n=57, sodium hyaluronate eye drops) and intervention group (n=63, sodium hyaluronate combined with rhEGF eye drops). The clinical efficacy, Break Up Time (BUT), schirmer I test (SLt), fluorescent test (FL) and ocular surface disease index (OSDI), the scale of quality of life for disease with visual impairment (SQOL-DVI), interleukin-6 (IL-6), tumor necrosis factor (TNF-a) level of the two groups were compared. The intervention group yielded remarkably higher effective rate than the control group (p<0.05). Markedly higher BUT, SLt, SQOL-DVI scores and lower OSDI scores were witnessed among patients in the intervention group than the control group (p<0.05). The clinical effect of sodium hyaluronate combined with rhEGF eye drops in the treatment of dry eye is superior to sodium hyaluronate alone, in terms of enhancing the stability of tear film, accelerating corneal healing, inhibiting the level of inflammatory factors and improving patients’ quality of life. en_US
dc.language.iso en en_US
dc.subject Clinical efficacy en_US
dc.subject inflammatory factors en_US
dc.subject quality of life en_US
dc.subject recombinant human epidermal growth factor en_US
dc.subject sodium hyaluronate en_US
dc.title Effects of sodium hyaluronate combined with rhEGF eye drops in patients with dry eye en_US
dc.type Article en_US


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