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Study of the radiotherapy sensitization of retroperitoneal lymph node metastasis in patients by sodium glycididazole

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dc.contributor.author Dong, Gui-zhi
dc.contributor.author Wang, De-guang
dc.contributor.author Gao, Hui-quan
dc.contributor.author Wang, Ling
dc.contributor.author Liu, Jing-jun
dc.contributor.author Du, Zhao-hui
dc.date.accessioned 2022-10-28T08:04:30Z
dc.date.available 2022-10-28T08:04:30Z
dc.date.issued 2015-09-04
dc.identifier.citation Dong, G. Z., Wang, D. G., Gao, H. Q., Wang, L., Liu, J. J., & Du, Z. H. (2015). Study of the radiotherapy sensitization of retroperitoneal lymph node metastasis in patients by sodium glycididazole. Pakistan Journal of Pharmaceutical Sciences, 28. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/13857
dc.description.abstract To observe the radiotherapy sensitization effect of retroperitoneal lymph node metastasis in patients by sodium glycididazole in recent clinical efficacy and toxicity. A total of 42 patients admitted with metastasis and recurrence of retroperitoneal lymph node from September 2006 to December 2009 were classified with the method of case-control. After three dimensional conformal radiation therapy with or without sodium glycididazole (800mg/m2) for sensitization, the results of recent clinical efficacy, relief of pain, and Karnofsky score were obtained. Tumor remission rate of patients in sensitization group (with sodium glycididazole) at post-radiotherapy 3 months was significant higher than that in control group (without sodium glycididazole) (52% vs. 24%; P<0.05). Oral dose of morphine daily, and Karnofsky score in anterior-posterior radiotherapy of patients in the sensitization group were significant different with those in the control group (93±12 and 42±6mg vs. 94±12 and 20±5mg and (65±4) and (90±9) vs. (64±5) and (80±10), respectively; P<0.01). Sodium glycididazole has positive radiotherapy sensitization to the metastasis or recurrence of retroperitoneal lymph node for digestive tract cancer, which could obviously improve the life quality or release the pain for patients. en_US
dc.language.iso en en_US
dc.publisher Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi. en_US
dc.subject Digestive system neoplasms en_US
dc.subject neoplasm metastasis en_US
dc.subject radiotherapy en_US
dc.subject three dimensionl conformal radiation therapy en_US
dc.subject sodium glycididazole en_US
dc.title Study of the radiotherapy sensitization of retroperitoneal lymph node metastasis in patients by sodium glycididazole en_US
dc.type Article en_US


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