Abstract:
Morchella is one of the most famous rare edible and medicinal fungi over the world. Highly nutritious and
immature cultivation techniques led to the high price and the markets have remained tight. The pathogenic bacteria were
serious in artificial cultivation of Morchella that affected the growth and yield of Morchella. Isolation of pathogenic
bacteria and metabolites were investigated in order to improve the artificial cultivation technology. The isolated strain
(YDJZ-01-01C) was identified by Gram staining and sequence of 16S rDNA. Structures of metabolites were confirmed
based on NMR spectra and literatures. However, the main products were uracil and thymine that considered as important
intermediate of anti-tumor 5-fluorouracil. Interestingly, a new synthetic pathway for preparation of uracil by
microorganism was found except for chemical synthesis. The new preparation pathway provided mild, green, sustainable
and environment friendly method to produce uracil that meets the needs of modern chemistry.
