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Analysis on diagnostic value of esophageal electrophysiological examination for positive atropine test

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dc.contributor.author Zhou, Jie
dc.contributor.author Sun, Laiguang
dc.contributor.author Zhu, Zhenjun
dc.contributor.author Zhou, Xia
dc.contributor.author Yun, Haiyan
dc.contributor.author Wang, Zhifang
dc.date.accessioned 2022-10-28T08:15:03Z
dc.date.available 2022-10-28T08:15:03Z
dc.date.issued 2015-09-09
dc.identifier.citation Zhou, J., Sun, L., Zhu, Z., Zhou, X., Yun, H., & Wang, Z. (2015). Analysis on diagnostic value of esophageal electrophysiological examination for positive atropine test. Pakistan Journal of Pharmaceutical Sciences, 28. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/13873
dc.description.abstract To discuss the cause of positive atropine test and the possible reason for false positive atropine test, providing a certain aids for clinical diagnosis and treatment. Eighty patients, conducted atropine test due to sinus bradycardia, with positive results from January 2010 to June 2013, were selected. Sinus heart rate were calculated and the changes in heart rhythm were observed by tracing electrocardiogram. Esophageal electrophysiological examination and atropine test were administrated. SPSS 10.0 statistical software was adopted and x2 test was applied for comparison. The positive results of atropine test and results of esophageal electrophysiological examination in different ages showed that as age grows, false positive rate of atropine test was significantly reduced, presenting statistically significant difference (x2=6.2821, p<0.05); The positive results of atropine test and results of esophageal electrophysiological examination in different heart rates showed that false positive rate of atropine test on those with bradycardia was smaller than those with significant bradycardia, presenting statistically significant difference (x2=5.1792, p<0.05). Simple sinus bradycardia is mostly caused by the increase of vagus nerve tension, almost negative in atropine test. Sick sinus syndrome (SSS) leads to abnormity in pacemaking and conduction induced by organic lesions in sinus nodes. Moreover, as the disease progresses, it is able to cause severe and persistent sinus bradycardia, almost positive in atropine test. Therefore, to identify the increase in vagus nerve tension or sinus bradycardia induced by SSS has a crucial clinical significance. Furthermore, the false positive and false negative profiles in atropine test can easily lead to misdiagnosis and mistreatment in clinic. en_US
dc.language.iso en en_US
dc.publisher Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi. en_US
dc.subject Atropine test en_US
dc.subject Positive en_US
dc.subject Sick sinus syndrome en_US
dc.subject Esophageal electrophysiological examination en_US
dc.title Analysis on diagnostic value of esophageal electrophysiological examination for positive atropine test en_US
dc.type Article en_US


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