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No.2(Supplementary),March 2017
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Browsing No.2(Supplementary),March 2017 by Issue Date

Browsing No.2(Supplementary),March 2017 by Issue Date

Now showing items 1-19 of 19

Pak. J. Pharm. Sci., Vol.30, No.2(Suppl), March 2017, pp.601-606 601 Studies on self-nanoemulsifying drug delivery system of flurbiprofen employing long, medium and short chain triglycerides

Daar, Junaid; Khan, Ahmad; Khan, Jallat; Khan, Amjad; Khan, Gul Majid (Faculty of Pharmacy & Pharmaceutical Sciences, 2017-03)

The aim of the study was to successfully design, formulate and evaluate self-nanoemulsifying drug delivery system (SNEDDS) of poorly aqueous soluble drug viz. flurbiprofen using long (LCT), medium (MCT) and short chain ...
In vivo antiviral potential of Glycyrrhiza glabra extract against Newcastle disease virus

Ashraf, Asma; Ashraf, Muhammad Mudassar; Rafiqe, Azhar; Aslam, Bilal; Galani, Saddia; Zafar, Shoaib; Asad, Farkhanda; Asghar, Rana Dawood; Akram, Sidra; Ahmed, Hamad; Shah, Syed Muhammad Ali; Asif, Rizwan (Faculty of Pharmacy & Pharmaceutical Sciences, 2017-03)

Newcastle disease is highly infectious viral disease causing huge economic losses worldwide. These losses can be prevented by control of viral diseases. Medicinal plants have been traditionally used for treatment of ...
Evaluation of three plant extracts against biofilm formation and expression of quorum sensing regulated virulence factors in Pseudomonas aeruginosa

Karbasizade, Vajihe; Dehghan, Parichehr; Sichani, Maryam Mohammadi; Shahanipoor, Kahin; Sepahvand, Shahriar; Jafari, Reyhaneh; Yousefian, Rozita (Faculty of Pharmacy & Pharmaceutical Sciences, 2017-03)

Following the increasing antibiotic resistance of pathogenic bacteria, the use of medicinal herbs as antibacterial agents has attracted growing attention. Pseudomonas aeruginosa is a human opportunistic pathogen that uses ...
Studies on self-nanoemulsifying drug delivery system of flurbiprofen employing long, medium and short chain triglycerides

Daar, Junaid; Khan, Ahmad; Khan, Jallat; Khan, Amjad; Khan, Gul Majid (Faculty of Pharmacy & Pharmaceutical Sciences, 2017-03)

The aim of the study was to successfully design, formulate and evaluate self-nanoemulsifying drug delivery system (SNEDDS) of poorly aqueous soluble drug viz. flurbiprofen using long (LCT), medium (MCT) and short chain ...
Pak. J. Pharm. Sci., Vol.30, No.2(Suppl), March 2017, pp.607-612 607 Correlation of thyroid antibodies with TSH, T3 and T 4 hormones in patients diagnosed with autoimmune thyroid disorders

Rabia, Mohammed W Al (Faculty of Pharmacy & Pharmaceutical Sciences, 2017-03)

The serum concentrations of anti-thyroid peroxidase (anti-TPO) and anti-thyroglobulin (anti-TG) antibodies are directly correlate in the induction and diagnosis of autoimmune thyroid disorders (AITDs). Therefore, the ...
To evaluate the efficacy and safety of CofNovex plus (EMA) syrup

Ali, Zubair; Daniyal, Muhammad; Adhia, Muhammad Khalid; Alam, Anees; Sarfaraz, Babar; Sattar, Abdul; Usmanghani, Khan (Faculty of Pharmacy & Pharmaceutical Sciences, 2017-03)

The cough and cold are very widespread conditions and a common purpose for advice in general practice. Utmost often the sign and symptoms of cough are produced by acute viral airway infection and the course is frequently ...
Nepeta rtanjensis (Lamiaceae), a plant endemic to the Balkans: Phenolic composition, antioxidant activity, and in vitro antigenotoxic effects in triiodothyronine-induced DNA damage in human lymphocytes

Neumüller, Jasna Bošnjak; Radaković, Milena; Djelić, Ninoslav; Gačić, Branka Vuković; Stevanović, Zora Dajić; Kolarević, Stoimir; Mišić, Danijela; Stanković, Milan; Vukčević, Jelena Knežević; Potparević, Biljana Spremo; Stanimirović, Zoran (Faculty of Pharmacy & Pharmaceutical Sciences, 2017-03)

The success of antioxidant therapy in hyperthyroidism implies that disease is mediated by oxidative stress, which is known as one of the causing agents of ageing, degenerative diseases, and cancer. The main objective of ...
Pak. J. Pharm. Sci., Vol.30, No.2(Suppl), March 2017, pp.613-617 613 Evaluation of hypocholesterolemic activity of extracts of Bidens odorata and Brickellia eupatorioides

Pena, Diana Patricia Moreno; Pérez, Paula Cordero; Rivas, Catalina Leos; Bucio, Leticia; Valdez, Jose Ezequiel Viveros; Espinosa, Linda Elsa Munoz; Rodríguez, Sergio Arturo Galindo; Morales, Catalina Rivas (Faculty of Pharmacy & Pharmaceutical Sciences, 2017-03)

We sought to evaluate the hypolipidemic activity of extracts of Bidens odorata and Brickellia eupatorioides using a model of hyperlipidemia induced in rats by Triton WR-1339 (300mg/kg intraperitoneally). The rats were ...
Effect of camel milk against renal toxicity in experimental rats

Al-Asmari, Abdulrahman; Abbasmanthiri, Rajamohamed; Al-Elawi, Abdulrahman M; Horaib, Ghaleb Al; Sadoon, Khalid Al; Al-Asmari, Bayan (Faculty of Pharmacy & Pharmaceutical Sciences, 2017-03)

Most of the antibiotics are associated with considerable side effects. Gentamicin (GM) is one of the most commonly used antibiotics, but has significant nephrotoxic side effects. Hence, the current study is investigating ...
Pak. J. Pharm. Sci., Vol.30, No.2(Suppl), March 2017, pp.573-578 573 The naphthoquinone plumbagin suppresses ADP-induced rat platelet aggregation through P2Y1 -PLC signaling pathway

Zhang, Qianrui; Liao, Xiaoyan; Wu, Fangjian (Faculty of Pharmacy & Pharmaceutical Sciences, 2017-03)

Plumbagin (PLB) isolated from Plumbago zeylanica L (Plumbaginaceae) was evaluated for the suppressive effect and mechanism on ADP induced rat platelet aggregation. Adult male SD rats were randomly divided into control ...
Expression of Twist protein in colorectal carcinoma and its effect on proliferation and invasion of colorectal cancer cells

Cheng, Chuanyao; Qin, Yaguang; Li, Yanhua; Pan, Jia; Wang, Jianjun (Faculty of Pharmacy & Pharmaceutical Sciences, 2017-03)

This paper aims to study Twist protein expression in colorectal carcinoma and its effect on the proliferation and invasion of colorectal cancer cells, and to explore its specific mechanism of promoting cancer. Tissues of ...
Pak. J. Pharm. Sci., Vol.30, No.2(Suppl), March 2017, pp.579-583 579 Formulation, Evaluation and release rate characteristics of medicated jelly of vitamin C

Ibrahim, Khalid A; Nawaz, Asma; Mumtaz, Shamim; Iqbal, Furqan Muhammad; Khan, Ahmad; Zaman, Shahiq uz; Salam, Nasser M Abd El; Ullah, Naseem; Hussain, Tajammal; Shah, Syed Nisar Hussain (Faculty of Pharmacy & Pharmaceutical Sciences, 2017-03)

Medicated jelly formulations are patient friendly dosage form for pediatric, geriatric and dysphagic patients. These formulations offer rapid dissolution and absorption of drugs through oral mucosa therefore show the early ...
Development of AD like symptoms following co-administration of AlCl3 and D-gal in rats: A neurochemical, biochemical and behavioural study

Liaquat, Laraib; Ahmad, Saara; Sadir, Sadia; Batool, Zehra; Khaliq, Saima; Tabassum, Saiqa; Emad, Shaista; Madiha, Syeda; Shahzad, Sidrah; Haider, Saida (Faculty of Pharmacy & Pharmaceutical Sciences, 2017-03)

Alzheimer’s disease (AD) is an age-related neurodegenerative disorder associated with neurochemical and neurobehavioural alterations. Aluminium (Al) is considered as a contributing factor in the etiology of several neu ...
Simultaneous determination of ACE inhibitors and dexibuprofen in active pharmaceutical ingredient, formulations and human serum by RP-HPLC

Sana, Aisha; Naveed, Safila; Qamar, Fatima; Shakeel, Sadia (Faculty of Pharmacy & Pharmaceutical Sciences, 2017-03)

The contemporary work describes a rapid and cost effective reversed phase High Performance Liquid Chromatography (RP-HPLC) method for the quantification of Captopril, Lisinopril and Dexibuprofen (DXP) simultaneously in ...
Combination of exendin-4 and DPP-4 silencing promoted angiogenesis of human coronary artery endothelial cells via activation of PI3K/Akt pathway

Qi, Xuewen; Liu, Haifeng; Mao, Limei; Sun, Peng; Kong, Degui (Faculty of Pharmacy & Pharmaceutical Sciences, 2017-03)

This study was aimed to explore the combined effects of Exendin-4 with dipeptidyl peptidase-IV (DPP-4) silencing on vascular endothelial growth factor (VEGF)-induced cell proliferation and angiogenesis in Human Coronary ...
Anti-hyperglycemic potential of Lactobacillus spp. in alloxan-induced Wistar rats

Bharti, Vandana; Mehta, Archana; Mourya, Gajendra Kumar; Ahirwal, Laxmi; Bajpai, Vivek K; Shukla, Shruti (Faculty of Pharmacy & Pharmaceutical Sciences, 2017-03)

This research was aimed to investigate anti-hyperglycemic effects of two Lactobacillus spp. on alloxan induced diabetic rats. Alloxan was administered intraperitoneally to induce the diabetic conditions in experimental ...
Expression of Th17 and CD4 + CD25 + T regulatory cells in peripheral blood of acute leukemia patients and their prognostic significance

Xiang, Mingli; Guo, Li; Yi Li, Yan Ma (Faculty of Pharmacy & Pharmaceutical Sciences, 2017-03)

To discuss the expression of T helper cell 17 (Th17) cells and CD4+ CD25 + Foxp3 + regulatory T cells (Treg) in peripheral blood (PB) of patients with acute leukemia (AL), and to explore the relationship between them and ...
Risk factors of neonatal mortality in Faisalabad, Pakistan

Bhatti, Sajjad Haider; Mamuna, Hiba Izzam; Aftab, Muhammad; Aslam, Muhammad; Aslam, Nosheen; Shah, Syed Muhammad Ali; Ahmed, Hamad; Akram, Muhammad (Faculty of Pharmacy & Pharmaceutical Sciences, 2017-03)

The objective of study was to find out major correlates of neonatal mortality. The main focus was in determining the impact of different demographic and health related characteristics of neonates and their mothers. A ...
Design and content determination of Genhuang dispersible tablet herbal formulation

Xin, Rui-hua; Liang, Ge; Zheng, Ji-fang (Faculty of Pharmacy & Pharmaceutical Sciences, 2017-03)

The aim of the present study was to optimize the shaping technology of the traditional herbal formula Genhuang dispersible tablets, and also establish a method for content determination. The optimal formulation of Genhuang ...

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