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In vivo antiviral potential of Glycyrrhiza glabra extract against Newcastle disease virus

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dc.contributor.author Ashraf, Asma
dc.contributor.author Ashraf, Muhammad Mudassar
dc.contributor.author Rafiqe, Azhar
dc.contributor.author Aslam, Bilal
dc.contributor.author Galani, Saddia
dc.contributor.author Zafar, Shoaib
dc.contributor.author Asad, Farkhanda
dc.contributor.author Asghar, Rana Dawood
dc.contributor.author Akram, Sidra
dc.contributor.author Ahmed, Hamad
dc.contributor.author Shah, Syed Muhammad Ali
dc.contributor.author Asif, Rizwan
dc.date.accessioned 2022-11-03T10:11:16Z
dc.date.available 2022-11-03T10:11:16Z
dc.date.issued 2017-03
dc.identifier.citation Ashraf, A., Ashraf, M. M., Rafiqe, A., Aslam, B., Galani, S., Zafar, S., ... & Asif, R. (2017). In vivo antiviral potential of Glycyrrhiza glabra extract against Newcastle disease virus. Pakistan journal of pharmaceutical sciences, 30. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/13914
dc.description.abstract Newcastle disease is highly infectious viral disease causing huge economic losses worldwide. These losses can be prevented by control of viral diseases. Medicinal plants have been traditionally used for treatment of different diseases since long. In this study the effect of extracts from Glycyrrhiza glabra leaves are investigated against Newcastle disease virus (NDV) by an in-vivo assay. Seven groups of nine-day-old embryonated chicken eggs were inoculated with various treatments of different plant extracts. All the groups except uninoculated negative control group were inoculated with velogenic NDV strain; five groups received different concentrations of the three extracts. Daily observe the rate of embryo survival. Allantoic fluid from treated eggs was collected for hem agglutination test. Results showed that embryo survival rate was higher 300μg/mL treated group as all the extracts showed antiviral activity. Similarly, the plant extracts effectively control virus as no viruses were identified in the allantoic fluids of all groups treated with low doses of plant. The current results have clearly verified that all the extracts especially that of methanol 300μg/mL from leaves of Glycyrrhiza glabra have strong antiviral activity against NDV in vivo. en_US
dc.language.iso en_US en_US
dc.publisher Faculty of Pharmacy & Pharmaceutical Sciences en_US
dc.subject Newcastle disease en_US
dc.subject Glycyrrhiza glabra en_US
dc.subject Haemagglutination test en_US
dc.subject in-vivo en_US
dc.subject poultry en_US
dc.title In vivo antiviral potential of Glycyrrhiza glabra extract against Newcastle disease virus en_US
dc.type Article en_US


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