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Pak. J. Pharm. Sci., Vol.30, No.2(Suppl), March 2017, pp.613-617 613 Evaluation of hypocholesterolemic activity of extracts of Bidens odorata and Brickellia eupatorioides

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dc.contributor.author Pena, Diana Patricia Moreno
dc.contributor.author Pérez, Paula Cordero
dc.contributor.author Rivas, Catalina Leos
dc.contributor.author Bucio, Leticia
dc.contributor.author Valdez, Jose Ezequiel Viveros
dc.contributor.author Espinosa, Linda Elsa Munoz
dc.contributor.author Rodríguez, Sergio Arturo Galindo
dc.contributor.author Morales, Catalina Rivas
dc.date.accessioned 2022-11-03T10:21:13Z
dc.date.available 2022-11-03T10:21:13Z
dc.date.issued 2017-03
dc.identifier.citation Moreno Pena, D. P., Pérez, P. C., Rivas, C. L., Bucio, L., Viveros Valdez, J. E., Munoz Espinosa, L. E., ... & Morales, C. R. (2017). Evaluation of hypocholesterolemic activity of extracts of Bidens odorata and Brickellia eupatorioides. Pakistan Journal of Pharmaceutical Sciences, 30. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/13928
dc.description.abstract We sought to evaluate the hypolipidemic activity of extracts of Bidens odorata and Brickellia eupatorioides using a model of hyperlipidemia induced in rats by Triton WR-1339 (300mg/kg intraperitoneally). The rats were divided into 5 groups of 3 rats each: normal control group, hyperlipidemic control group, hyperlipidemic with 20 mg/kg atorvastatin, hyperlipidemic with 300 mg/kg B. odorata extract, and hyperlipidemic with 300mg/kg B. eupatorioides extract, respectively. After 10 d of treatment by intragastric administration, the extract of B. odorata caused a significant decrease of serum total cholesterol and triglyceride levels without altering the liver enzymes aspartate transaminase and alanine aminotransferase. In addition, the extract had antioxidant potential as shown by the 2,2′-diphenyl-1- picrylhydrazyl technique. These findings indicate that B. odorata has potential as a hypolipidemic agent and might be beneficial in treatment of hyperlipidemia and atherosclerosis. en_US
dc.language.iso en_US en_US
dc.publisher Faculty of Pharmacy & Pharmaceutical Sciences en_US
dc.subject Cholesterol en_US
dc.subject hypercholesterolemia en_US
dc.subject plant extracts en_US
dc.subject triglycerides en_US
dc.title Pak. J. Pharm. Sci., Vol.30, No.2(Suppl), March 2017, pp.613-617 613 Evaluation of hypocholesterolemic activity of extracts of Bidens odorata and Brickellia eupatorioides en_US
dc.type Article en_US


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