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Design and content determination of Genhuang dispersible tablet herbal formulation

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dc.contributor.author Xin, Rui-hua
dc.contributor.author Liang, Ge
dc.contributor.author Zheng, Ji-fang
dc.date.accessioned 2022-11-03T10:25:54Z
dc.date.available 2022-11-03T10:25:54Z
dc.date.issued 2017-03
dc.identifier.citation Xin, R. H., Liang, G., & Zheng, J. F. (2017). Design and content determination of Genhuang dispersible tablet herbal formulation. Pakistan Journal of Pharmaceutical Sciences, 30. en_US
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/13942
dc.description.abstract The aim of the present study was to optimize the shaping technology of the traditional herbal formula Genhuang dispersible tablets, and also establish a method for content determination. The optimal formulation of Genhuang dispersible tablets was determined based on the results of single factor test and orthogonal design test. The disintegration was used as the main study indicator. The proportion of each adjuvant in the optimal formulation consisted of 40% MCC as bulking agent, 15% PVPP and 7% L-HPC as disintegrant, ethanol as adhesive, CSD as lubricant, preparing the dispersible tablets with wet granulation. The content of baicalin in Genhuang dispersible tablets was determined by RP-HPLC method, the C18 column (150×4.6 mm, 10μm) was used, the mobile phase was methanol- water-phosphoric acid (47: 53: 0.2) with the flow rate of 1mL/min, the detection wavelength was at 280 nm and the column temperature was 30. en_US
dc.language.iso en_US en_US
dc.publisher Faculty of Pharmacy & Pharmaceutical Sciences en_US
dc.subject Genhuang dispersible tablet en_US
dc.subject orthogonal design en_US
dc.subject disintegration time en_US
dc.subject content determination en_US
dc.title Design and content determination of Genhuang dispersible tablet herbal formulation en_US
dc.type Article en_US


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