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  • Anti-diabetic activity of aqueous extract of Ipomoea batatas L. in alloxan induced diabetic Wistar rats and its effects on biochemical parameters in diabetic rats 
    Shagufta Kamal; Naheed Akhter; Khan, Samreen Gul; Shumaila Kiran; Tahir Farooq; Muhammad Akram; Syed Muhammad Ali Shah; Imtiaz Mahmood Tahir; Muhammad Akhlaq; Fahad Said; Jawad Zaheer (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-07-13)
    Diabetes is a condition where the fasting blood glucose level elevated above the normal range (80-120mg/dL). This increase in blood glucose level may be due to the insulin deficiency i.e. insulin dependent diabetes mellitus ...
  • Anti-inflammatory effect of the compounds from the flowers of Trollius chinensis 
    Liu, Li-Jia; Hu, Xiu-Hua; Guo, Li-Na; Wang, Ru-Feng; Zhao, Qi-Tao (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-09-25)
    In order to investigate the anti-inflammatory activity of flavonoids, phenolic acids, and alkaloids from the flowers of Trollius chinensis, some representative compounds, namely, orientin, 2"-O-β-L-galactopyranosylorientin, ...
  • Anti-inflammatory terpenoids from Cyperus rotundus rhizomes 
    Sabrin Ragab Mohamed Ibrahim; Gamal Abdallah Mohamed; Maan Talaat Abdullah Khayat; Mohamed Fathalla Zayed; El-Kholy, Amal Abd-Elmoneim Soliman (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-07-01)
    Phytochemical investigation of the methanolic extract of Cyperus rotundus L. (Cyperaceae) rhizomes afforded a new norterpenoid with an unprecedented carbon skeleton, namely cyperalin A (1) and sugetriol triacetate (2). ...
  • Antibacterial assay and reversion of carbon tetrachloride induced liver damage on wistar mice by Vernonia amygdalina. Delile 
    Chukwuemeka, Nwinyi Obinna; Oyebisi, Smith Oluwakemi; Adebisi Oluwadare, Olugbuyiro Joseph; Oladapo, Rotimi Solomon; Berka, Njobeh Patrick (Karachi: Pakistan Botanical Society, University of Karachi, 2018-07-20)
    In this study Vernonia amygdalina. Delile stem and leaves were evaluated for anti-cancer and antibacterial actions against selected microorganisms. The crude plant extracts were extracted using methanol and fractionated ...
  • Antibiotics use and drug resistance analysis of neurology patients’ infection 
    Xiaohua, Liu; Wei, Huang; Yanxiang, Gao (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-09-09)
    Recent studies have shown that nosocomial infection is an important factor affecting the quality and service level of neurology. Based on the characteristics of neurology patients, the application of antibacterial drugs ...
  • Anticholinergic drug atropine diminishes newly formed fear memory in male rats 
    Sahar Rafiq; Saara Ahmad; Fatima Ahmed; Zehra Batool; Saad Bilal Ahmed; Sadia Saleem; Fizza Naqvi; Laraib Liaquat; Asia Afzal; Saida Haider (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-05-15)
    Post-traumatic stress disorder (PTSD) is a condition which is triggered shortly after experiencing traumatic events. PTSD is complicated by the fact that people with PTSD often develop additional disorders such as phobias, ...
  • Anticoagulant effects of Rivaroxaban after surgical fixation of spinal fracture 
    Chunhong, Liang; Jin, Lv; Qin, Zhang; Guohui, Xie (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-05-20)
    In recent years, the concept of treatment after surgery in the department of orthopedics has changed from hemostasis to anticoagulant. This article analyses the safety and effectiveness of anticoagulants for prophylacti ...
  • Antidiarrhoeal effects of the methanol extract of the aerial parts of Mitracarpus villosus 
    John-Africa, Lucy Binda (Karachi: Pakistan Botanical Society, University of Karachi, 2018-07-20)
    Mitracarpus villosus (S.W) DC is used as treatment for diarrhoea and dysentery in some communities of West Africa. This study aimed to investigate the antidiarrhoeal effects of the methanol extract of the aerial parts of ...
  • Antifungal and cytotoxic activities of selected medicinal plants from Malaysia 
    Chan, Yik Sin; Cheah, Yit Hong; Chong, Poh Zen; Lai Khor, Hui; Siang Teh, Wen; Khoo, Kong Soo; Chooi Ong, Hean; Weng Sit, Nam (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    This study was conducted to investigate the antifungal potential and cytotoxicity of selected medicinal plants from Malaysia. The extracts from the stem of Cissus quadrangularis and the leaves of Asplenium nidus, Pereskia ...
  • Antihyperglycemic effect of Conocarpus erectus leaf extract in alloxaninduced diabetic mice 
    Syed Ali Raza; Chaudhary, Ayoub Rashid; Muhammad Waseem Mumtaz; Abdul Ghaffar; Ahmad Adnan; Abdul Waheed (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-03-06)
    Synthetic drugs have widely been helpful in management of diabetes mellitus type 2. However, side effects associated with synthetic drugs serve as an impetus to explore plants as alternate mode of treatment. The hydroethanolic ...
  • Antihyperlipidemic and anti-hyperglycemic effects of Cymbopogon jwarancusa in high-fat high-sugar diet model 
    Khan, Sarah Jameel; Syeda Afroz; Khan, Rafeeq Alam (Karachi: Pakistan Botanical Society, University of Karachi, 2018-07-20)
    Hyperlipidemia is the root cause for development of atherosclerosis, coronary heart disease, diabetes mellitus, obesity, hypertension and cerebral palsy. Cymbopogon jwarancusa is an aromatic grass (Rusha grass, khavi grass) ...
  • Antileishmanial, insecticidal and phytotoxic potential of leaves and stems of Rumex nervosus Vahl. 
    Khan, Rasool; Mohammed Mansour Quradha; Abdullah Qasem Saif; Jawad Ali; Abdur Rauf (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-09-20)
    Biological assays including; phytotoxicity, brine shrimp lethality, antileishmanial and insecticidal activities were carried out on crude methanolic extracts of stems and leaves of R. nervosus and their fraction namely; ...
  • Antimicrobial and antiurease potential of Diorganotin(IV) Schiff bases 
    Khan, Shuja Abbas; Rehan Naeem; Shah Hussain; Saqib Ali; Naveed Muhammad; Zahid Hussain; Shaukat Shujah (Karachi: Pakistan Botanical Society, University of Karachi, 2018-07-20)
    Six new diorganotin (IV) Schiff bases, [(CH3)2SnL] (I), [(C2H5)2SnL] (II), [(n-C4H9)2SnL] (III), [(C6H5)2SnL] (IV), [(CH2C6H5)2SnL] (V) and [(n-C8H17)2SnL] (VI) where L = N-(5-bromo-2-oxidobenzylidene)phenylacetohydrazide, ...
  • Antimicrobial susceptibility profile, Adherence and invasion to mammalian cells of Brucella melitensis isolates 
    Ahmed Farouk Basyony; Mohammad Mabrouk Aboulwafa; Mohamed Mostafa Hafez; Khalid Abdel Samei Abou-Gazia (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-11-10)
    Susceptibilities of 66 Brucella isolates were tested in vitro. All isolates were susceptible to doxycycline, gentamic in and streptomycin. In addition, propyl paraben, cresol and benzalkoniumchloride were found to be the ...
  • Antinociceptive, antimicrobial potential and phytochemical screening of different solvent extracted samples from the stem of Acer pentapomicum 
    Khan, Shehla; Jehan Bakht; Mohammad Shafi (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-07-02)
    The present study investigates the antinociceptive, antimicrobial activity and phytochemical assessment of samples from A. pentapomicum. Different microbes were tested using disc diffusion assay at three concentrations ...
  • Antioxidant and xanthine oxidase inhibitory activity of Eucommia ulmoides Oliver leaf extracts 
    Guiming Fu; Huoyan Tong; Hailong Zeng; Bin Zou; Jianxin Chai; Lunning Zhang; Mingyong Xie; Feng Chen; Yin Wan (Karachi: Pakistan Botanical Society, University of Karachi, 2018-07-20)
    The total phenolic content, flavonoid content, in vitro xanthine oxidase (XOD) inhibitory activity and antioxidant activity (AA) of Eucommia ulmoides Oliver leaf extracts were investigated. The AA investigations included ...
  • Antioxidant capacity and polyphenolic content of the Echinocystis lobata (Michx.) Torr. et A.Gray flowers 
    Ielciu, Irina; Hanganu, Daniela; Păltinean, Ramona; Vlase, Laurian; Frédérich, Michel; Gheldiu, Ana-Maria; Benedec, Daniela; Crişan, Gianina (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-03-12)
    Echinocystis lobata (Michx.) Torr. et A.Gray is a spontaneous species in the Romanian flora, lesser studied by scientific literature, but which has proved significant activities in traditional medicine. The present study ...
  • Antioxidant, cytotoxicity, protein kinase inhibition and antibacterial activities of Fragaria × ananassa leaves 
    Ihsan Khan; Saira Tabassum; Tofeeq-ur-Rehman; Muhammad Ikram; Ihsan ul Haq; Muhammad Zia (Karachi: Pakistan Botanical Society, University of Karachi, 2018-07-20)
    Fragaria × ananassa leaves extracts prepared in different solvents were subject for antioxidative, cytotoxicity, protein kinase inhibition and antibacterial activities. The extracts showed varying activities depending upon ...
  • Antiulcer activity of methanol-chloroform extract of Channa striatus fillet 
    Azemi, Ahmad Khusairi; Abd Rahim, Mohd Hafiz; Mamat, Siti Syariah; Mat Jais, Abdul Manan; Zakaria, Zainul Amiruddin (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    Channa striatus (Haruan) is Malaysian freshwater fish that is traditionally used to treat ailments related to wound and also ulcers. The aimed of the present study was to determine the mechanisms of anti-ulcer activity of ...
  • Apoptosis and antitumor effects between β-elemene and astragaloside and drug mechanism analysis 
    Liping, Shi; Tingting, Chen; Zheng, Yuan; Tian, Xie; Haibo, Cheng (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-09-14)
    β-elemene is an effective anticancer drug extracted from Rhizoma curcumae. It is a non cytotoxic antineoplastic agent, which can obviously inhibit the proliferation of tumor cells. In this paper, we observed the proliferation ...

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