No.5 September, 2017: Recent submissions

  • Ricinus cmmunis: Ethnomedicinal uses and pharmacological activities 
    Khan Marwat, Sarfaraz; ur-Rehman, Fazal; Ahmad Khan, Ejaz; Safdar Baloch, Mohammad; Sadiq, Muhammad; Ullah, Imdad; Javaria, Sadaf; Shaheen, Salma (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2017-10-09)
    Ricinus cmmunis L. (Castor oil plant) is an important medicinal plant belonging to family Euphorbiaceae. Its phytochemistry, biological and pharmacological activities, and ethnomedicinal uses have been reviewed in the ...
  • Lactic acid bacteria in traditional fermented Asian foods 
    Azam, Mariya; Mohsin, Mashkoor; Ijaz, Hira; Ruqia Tulain, Ume; Adnan Ashraf, Muhammad; Fayyaz, Ahad; ul Abadeen, Zain; Kamran, Qindeel (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2017-10-08)
    Lactic acid bacteria play vital roles in various fermented foods in Asia. This paper reviews many types of the world's lactic acid fermented foods and discusses the beneficial effects of lactic acid fermentation of food. ...
  • Antidiabetic effects of native date fruit Aseel (Phoenix dactylifera L.) in normal and hyperglycemic rats 
    Ahmed, Shadab; Alam Khan, Rafeeq; Jamil, Subia; Afroz, Syeda (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2017-10-07)
    Change in dietary pattern, sedentary life style and increasing stresses are contributing factors for high prevalence of diabetes mellitus. Diabetic complications often lead to cardiovascular diseases, hypertension and ...
  • Colonization rates and immune status of children against Streptococcus pneumoniae before the introduction of pneumococcal conjugate vaccine 
    Bibi, Safia; Ruba Siddiqui, Taranum; Furqan Hassan, Syed; Ahmed, Waquaruddin (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2017-10-06)
    Pneumococcal infections contribute to high morbidity and mortality in Pakistan. Pneumococcal colonization rates and immune status of children before and after vaccination can serve as an important indicator to determine ...
  • Screening of medicinally important Berberis lyceum for their antimicrobial activity by disc diffusion assay 
    Bakht, Jehan; Iftikhar, Zainab; Shafi, Mohammad; Iqbal, Arshad (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2017-10-05)
    The present research was focused on the anti-microbial activities of different solvent extracted fractions from commercial available and fresh plants of Berberis lyceum against Gram positive, Gram-negative bacteria and ...
  • Urease inhibitory activity of Hippophae rhamnoids and Cassia fistula 
    Ali Khan, Barkat; Akhtar, Naveed; Khan, Haroon; Mustafa, Ghulam; Rasul Niazi, Zahid; Menaa, Farid (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2017-10-04)
    The rational use of plants as medicine is traced back over five epochs to ancient documents of early civilizations and is certainly as old as mankind. These medicines originally developed from crude drugs like tinctures ...
  • Evaluation of dynamics of derivatization and development of RPHPLC method for the determination of amikacin sulphate 
    Shehzadi, Naureen; Hussain, Khalid; Tanveer Khan, Muhammad; Salman, Muhammad; Islam, Muhammad (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2017-10-03)
    The absence of chromophore and/or conjugated system, prerequisite for UV and florescent light detection, or absorbance at very low wavelength necessitates the development of simple and reliable methods for the determination ...
  • Bile acids and bile alcohols from Muraenesox bagio, Pomadasys argenteus and Lobeo rohita 
    Rasheed, Munawwer; Ahmed, Mansoor; Hassan, Amir; Nazim, Urooj; Alam Khan, Rafeeq; Kamal, Mustafa; Abdur Rashid, Mohammad (2017-10-02)
    Gallbladders bile of three well known commercial fish of South Asia region named Muraenesox bagio (locally called bam), Pomadasys argenteus (dother) and Lobeo rohita (rohu) were analysed on GC-MS, after derivatising the ...
  • Moxifloxacin reduces Stenotrophomonas maltophilia adhesion to mouse intestinal tract in vitro 
    Khadem Zgair, Ayaid; A Ghafil, Jenan; M. Radif, Hala; Naser Radhi, Shamim; H Hafiz, Mohammad; Fadhel Abbas Albaayit, Shaymaa (2017-10-01)
    Stenotrophomonas maltophilia is an important opportunistic pathogen that affects immunocompromised individuals. Viable bacterial count method was used to count the number of adhered bacteria. The current study showed the ...
  • In vitro antioxidant and antibacterial activity of various extracts from exocarps and endocarps of walnut 
    Zarghami Moghaddam, Parastoo; Mohammadi, Ameneh; Feyzi, Peyman; Alesheikh, Peiman (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2017-09-28)
    Juglans regia seed has been used in traditional medicines as antimicrobial, antihelmintic and anti-diarrhoeal. In the present study, the antibacterial capabilities dichloromethane, ethyl acetate, methanol and aqueous ...
  • Synthesis, enzyme inhibition and molecular docking studies of 1- Arylsulfonyl-4-phenylpiperazine derivatives 
    Athar Abbasi, Muhammad; Anwar, Ambreen; Rehman, Aziz-ur; Zahra Siddiqui, Sabahat; Rubab, Kaniz; Adnan Ali Shah, Syed; Arif Lodhi, Muhammad; Ali Khan, Farman; Ashraf, Muhammad; Alam, Umber (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2017-09-27)
    Heterocyclic molecules have been frequently investigated to possess various biological activities during the last few decades. The present work elaborates the synthesis and enzymatic inhibition potentials of a series ...
  • Evaluation of Artemisia scoparia for hemostasis promotion activity 
    Sajid, Moniba; Rashid Khan, Muhammad; Ali Shah, Naseer; Sher Waris, Tayyaba; Younis, Tahira; Ullah, Shafi; Ahmed, Nadeem (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2017-09-26)
    Excessive hemorrhage through any reasons is a life threatening process. Artemisia scoparia of family Asteraceae has been used in local system of medicine to stop bleeding from wounds and in injuries, antiseptic, in healing ...
  • Model design for screening effective Antihyperlipidemic drugs using zebrafish system 
    Chen, Kan; Wang, Chang-qian; Fan, Yu-qi; Xie, Yu-shui; Yin, Zhao-fang; Xu, Zuo-jun; Zhang, Hui-li; Cao, Jia-tian; Wang, Yue; Gao, Lin (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2017-09-25)
    The purpose of this paper was to explore a new method for screening lipid-lowering drugs in zebrafish models. The suitable drug concentrations of atorvastatin (ATV), fenofibrate (FEF) and ezetimibe (EZE) were first ...
  • Serum levels of leptin, zinc and tryptophan with obesity: A case-control study 
    Samad, Noreen (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2017-09-24)
    The obesity epidemic has turn into a major health threat worldwide and extensively responsible for the increased incidence of many diseases such as diabetes, cardiovascular disease and certain types of cancer. Excessive ...
  • Potential of Nigella sativa seed aqueous extract in ameliorating quinine-induced thrombocytopenia in rats 
    Saadia, Mubshara; Rehman, Saba; Robin, Sehrish; Ruby, Tahira; Sher, Muhammad; Ahmad Siddiqui, Waseeq; Ahmad Khan, Mahmood (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2017-09-23)
    Dengue infection is rapidly spreading in most of the countries of south Asia. It is of utmost importance to explore the plants with “anti-thrombocytopenic activity” the dreadful response of dengue fever. The present study ...
  • Curcumin inhibits the proliferation and induces apoptosis in HT-29 cell lines through a reactive oxygen species (ROS)-dependent mechanism 
    Wang, Jinbo; Qi, Lili; Mei, Lehe; Wu, Zhige (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2017-09-22)
    Curcumin, a natural pigment extracted from Curcuma longa, has anti-carcinogenic activities in many cancer cell lines. The molecular mechanism of apoptosis induced by curcumin are still unknown. In the current study, we ...
  • Effects of temperature and storage on the antioxidant potential, polyphenols and Vitamin-C contents of azadirachta indica leave aqueous extract 
    ullah, Shafqat; khan, Rasool; Hussain, Arshad; Ullah, Asad; ur-Rehman, Khaliq (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2017-09-21)
    The aim of the study was to investigate the effects of effects of storage and temperature on the antioxidant potential, vitamin-C contents, total as well as selected individual phenolic acids and flavonoids of fresh aqueous ...
  • Moxifloxacin reduces Stenotrophomonas maltophilia adhesion to mouse intestinal tract in vitro 
    Khadem Zgair, Ayaid; A Ghafil, Jenan; M. Radif, Hala; Naser Radhi, Shamim; H Hafiz, Mohammad; Fadhel Abbas Albaayit, Shaymaa (Karachi: Faculty of Pharmacy and Pharmaceutical Sciences, University of Karachi, 2017-10-03)
    Stenotrophomonas maltophilia is an important opportunistic pathogen that affects immunocompromised individuals. Viable bacterial count method was used to count the number of adhered bacteria. The current study showed the ...
  • Synthesis of 2-[(5-benzyl-1,3,4-oxadiazole-2yl)sulfanyl]-N- (arylated/arenylated) acetamides as antibacterial and acetyl cholinesterase inhibitors 
    Zahra Siddiqui, Sabahat; Athar Abbasi, Muhammad; Rehman, Aziz-ur; Ashraf, Muhammad; Mirza, Bushra; Ismai, Hammad (Karachi: Faculty of Pharmacy and Pharmaceutical Sciences, University of Karachi, 2017-09-30)
    The synthetic methodology is carried out in multistep which was initiated as phase I by utilizing Fischer esterification methodology of 2-phenylacetic acid (1) to ethyl-2-phenylacetate (2). The ester was reacted with ...
  • Essential minerals and phytic acid in legumes with reference to their nutritive and medicinal properties 
    Ahmed, Salman; Bin Zafar Mahmood, Saad; Mohtasheemul Hasan, Muhammad; Alam Mahmood, Zafar (Karachi: Faculty of Pharmacy and Pharmaceutical Sciences, University of Karachi, 2017-09-29)
    Three commonly used legumes, Macrotyloma uniflorum (Lam.) Verdc., Phaseolus lunatus Linn., and Phaseolus vulgaris Linn., were subjected to determine their minerals and phytic acid contents to correlate their nutritional ...

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