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Screening of antitumor polypeptide drug and enhanced CT imaging based on drug target analysis

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dc.contributor.author Shao, Chenghui
dc.contributor.author Xu, Shuangshuang
dc.contributor.author Song, Yang
dc.contributor.author Zhu, Dong
dc.date.accessioned 2022-11-17T10:10:39Z
dc.date.available 2022-11-17T10:10:39Z
dc.date.issued 2017-09-20
dc.identifier.citation Shao, C., Xu, S., Song, Y., & Zhu, D. (2017). Screening of antitumor polypeptide drug and enhanced CT imaging based on drug target analysis. Pakistan Journal of Pharmaceutical Sciences, 30. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/14049
dc.description.abstract Molecular targeted antitumor drugs is a major progress in recent years, these drugs usually target specific molecules to tumor cell signaling pathways, reduce toxicity, and can achieve individualized treatment. In this study, we screened three polypeptide proteins by yeast two hybrid systems, which could inhibit tumor growth obviously. The results of this study are expected to further develop new antitumor drugs. Moreover, by using contrast-enhanced computed tomography (CECT) imaging, this study proposes an algorithm for the computer-aided diagnosis (CAD) and classification of adrenal tumors. The experimental results demonstrate an excellent classification performance of this algorithm. Therefore, the method proposed in this paper may accurately locate and qualitatively diagnose the adrenal tumor in an effective manner, thereby providing important references for treatment. en_US
dc.language.iso en en_US
dc.publisher Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi. en_US
dc.subject Antineoplastic drugs en_US
dc.subject oncology en_US
dc.subject drug target en_US
dc.subject yeast two hybrid. en_US
dc.title Screening of antitumor polypeptide drug and enhanced CT imaging based on drug target analysis en_US
dc.type Article en_US


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