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Browsing Volume 21 by Issue Date

Browsing Volume 21 by Issue Date

Now showing items 1-12 of 12

CARDIOPROTECTIVE EFFECTS AND MECHANISM OF ACTION OF POLYPHENOLS EXTRACTED FROM PROPOLIS AGAINST DOXORUBICIN TOXICITY

ALYANE, M; W KEBSA, L BENGUEDOUAR; BOUSSENANE, HN; ROUIBAH, H; LAHOUEL, M (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2008-07-01)

Propolis is one of the major hive products of bees and is rich in flavonoids, which are known for antioxidant activities. It is well known that the chemical properties of phenolic acids or flavonoids, in terms of ...
ANTIBACTERIAL ACTIVITY OF THYMUS DAENENSIS METHANOLIC EXTRACT

MOJAB, FARAZ; POURSAEED, MAHSHID; MEHRGAN, HADI; PAKDAMAN, SHIMA (Karachi:Pakistan Journal of Botany, Botanical Garden, University of Karachi, 2008-07-02)

Medicinal plants are potential of antimicrobial compounds. The present study deals with the antibacterial activity of methanolic extract of Thymus daenensis. Aerial parts of the plant were collected from Alvand mountainside ...
CHEMOMETRIC DETERMINATION OF RABEPRAZOLE SODIUM IN PRESENCE OF ITS ACID INDUCED DEGRADATION PRODUCTS USING SPECTROPHOTOMETRY, POLAROGRAPHY AND ANODIC VOLTAMMETRY AT A GLASSY CARBON ELECTRODE

MONEEB, S MARWA (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2008-07-03)

Chemometric stability indicating methods are presented for the determination of rabeprazole sodium in presence of its acid induced degradation products using spectrophotometry, differential pulse polarography and differential ...
PHARMACOKINETICS OF CIPROFLOXACIN IN NORMAL RABBITS AND CHANGES OBSERVED IN INDUCED DEHYDRATED STATE

BASHIR, SAJID; JAMSHAID, MOHAMMAD; AHMAD, BASHIR; IQBAL, JAVEID (Karachi:Pakistan Journal of Botany, Botanical Garden, University of Karachi, 2008-07-04)

The pharmacokinetics of ciprofloxacin following oral administration of a single dose of 20mg/Kg body weight was investigated in normal rabbits and changes were observed in water-deprived rabbits. High performance liquid ...
A COMPARATIVE STUDY OF DISSOLUTION CHARACTERISTICS OF POLYMERIC AND WAX GRANULATIONS OF THEOPHYLLINE AND THEIR TABLETS

U UHUMWANGHO, MICHAEL; S OKOR, ROLAND (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2008-07-05)

Matrix (non disintegrating) granules of theophylline have been formed and their dissolution characteristics investigated for sustained release application. The polymeric granulations were formed by massing the drug powder ...
THE EFFECT OF MAGNESIUM SUPPLEMENTATION ON GLUCOSE AND INSULIN LEVELS OF TAE-KWAN-DO SPORTSMEN AND SEDENTARY SUBJECTS

CINAR, VEDAT; POLAT, YAHYA; MOGULKOC, RASIM; NIZAMLIOGLU, MUSTAFA; KERIM KASIM BALTACI, ABDUL (Karachi:Pakistan Journal of Botany, Botanical Garden, University of Karachi, 2008-07-06)

This study was performed to determine how the magnesium supplementation for a 4-week period affects the glucose and insulin levels at rest and at exhaustion in sportsmen. This is a 4 week study performed on 30 healthy ...
DESIGN AND IN VIVO EVALUATION OF CARVEDILOL BUCCAL MUCOADHESIVE PATCHES

THIMMASETTY, J; PANDEY, GS; BABU, PR SATHESH (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2008-07-07)

The buccal region offers an attractive route of administration for systemic drug delivery. Carvedilol (dose, 3.125-25 mg) is β-adrenergic antagonist. Its oral bioavailability is 25-35% because of first pass metabolism. Buccal ...
EVALUATION OF ANTIOXIDANT PROPERTIES OF SILYMARIN AND ITS POTENTIAL TO INHIBIT PEROXYL RADICALS IN VITRO

ASGHAR, ZARBAN; MASOOD, ZIAEE (Karachi:Pakistan Journal of Botany, Botanical Garden, University of Karachi, 2008-07-08)

Silymarin (milk thistle) has been used for centuries as a natural remedy for diseases of liver and biliary tract. The present study was carried out to evaluate the in vitro free radical scavenging activity and ...
PROTECTIVE EFFECT OF CAPTOPRIL AGAINST CISPLATIN-INDUCED NEPHROTOXICITY IN RATS

M EL-SAYED, EL-SAYED; F ABD-ELLAH, MOHAMED; M ATTIA, SABRY (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2008-07-09)

This study has been initiated to determine whether captopril, an angiotensin-converting enzyme (ACE) inhibitor containing sulfhydryl (-SH) group can protect against cisplatin-induced nephrotoxicity in rats. A single dose ...
BEHAVIORAL EFFECTS OF 1-(m-CHLOROPHENYL)PIPERAZINE (m-CPP) IN A RAT MODEL OF TARDIVE DYSKINESIA

SAMAD, NOREEN; A HALEEM, MUHAMMAD; J HALEEM, DARAKHSHAN (Karachi:Pakistan Journal of Botany, Botanical Garden, University of Karachi, 2008-07-10)

The present study was designed to monitor the responsiveness of 5-hydroxy tryptamine (5-HT)-2C receptor in rats treated with haloperidol exhibiting tardive dyskinesia (TD). Results show that haloperidol injected at a ...
HEPATOTOXICITY OF CARBON TETRACHLORIDE: PROTECTIVE EFFECT OF GONGRONEMA LATIFOLIUM

OE, ETIM; EJ, AKPAN; IF, USOH (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2008-07-11)

The protective effect of the ethanolic extract of Gongronema latifolium (GLE) on carbon tetrachloride (CCI4) induced hepatic toxicity was studied. Liver enzymes studied included alanine aminotransferase (ALT), aspartate ...
EFFECTIVENESS OF SILDENAFIL CITRATE (VIAGRATM) AND TADALAFIL (CIALISTM) ON SEXUAL RESPONSES IN SAUDI MEN WITH ERECTILE DYSFUNCTION IN ROUTINE CLINICAL PRACTICE

TABREZ ALI, SYED (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2008-07-12)

Satisfaction with the sexual experience is considered important when evaluating the impact of treatments for erectile dysfunction, yet enhanced satisfaction has been infrequently assessed in the sexual trials. We evaluated ...

Now showing items 1-12 of 12

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