dc.contributor.author |
Maimaitiyiming, Dilinuer |
|
dc.contributor.author |
Kamilijiang, Mayila |
|
dc.contributor.author |
Xiaerfuding, Xiadiya |
|
dc.contributor.author |
Wen Hui, Shi |
|
dc.contributor.author |
Abudureyimu, Meiliwan |
|
dc.contributor.author |
Hajinisha, Hajinisha |
|
dc.contributor.author |
Aikemu, Ainiwaer |
|
dc.date.accessioned |
2022-11-18T06:15:46Z |
|
dc.date.available |
2022-11-18T06:15:46Z |
|
dc.date.issued |
2017-09-07 |
|
dc.identifier.citation |
Maimaitiyiming, D., Kamilijiang, M., Xiaerfuding, X., Hui, S. W., Abudureyimu, M., & Aikemu, A. (2017). Protective effects of traditional Uighur medicine-seeds of Nigella glandulifera Freyn extracts against ccl 4-induced acute hepatic injury in mice. Pakistan Journal of Pharmaceutical Sciences, 30(5). |
en_US |
dc.identifier.issn |
1011-601X |
|
dc.identifier.uri |
http://142.54.178.187:9060/xmlui/handle/123456789/14067 |
|
dc.description.abstract |
To explore the protective effects of Traditional Uighur medicine Seeds of Nigella glandulifera Freyn (SNF)
extracts against CCl4-induced acute hepatic injury in mice. Hepatic injury mice models induced by intraperitoneal injection of 0.1% CCl4 olive oil were established. Liver and spleen coefficient, Serum ALT and AST activities, SOD, GSH-Px activities and MDA content in hepatic homogenate were measured and the hepatic histological changes were observed by optical microscope. Serum activities of ALT (P<0.01) and AST (P<0.05) in Alcohol extraction group was decreased; Activity of hepatic homogenate SOD increased in Alcohol extraction group and Water extraction group significantly (P<0.05). Content of MDA was decreased in Alcohol extraction group (P<0.01). Water extracts of SNF have obvious protective effects on hepatic injury induced by CCl4 in mice. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
Karachi: Faculty of Pharmacy and Pharmaceutical Sciences, University of Karachi |
en_US |
dc.subject |
Traditional Uighur medicine |
en_US |
dc.subject |
seeds of Nigella glandulifera Freyn |
en_US |
dc.subject |
carbon tetrachloride (CCl) |
en_US |
dc.subject |
acute liver injury |
en_US |
dc.title |
Protective effects of traditional Uighur medicine-seeds of Nigella glandulifera Freyn extracts against ccl4-induced acute hepatic injury in mice |
en_US |
dc.type |
Article |
en_US |