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Effect of puerarin on type II diabetes mellitus with orthopaedic footwear

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dc.contributor.author Yu, Qinyuan
dc.contributor.author Han, Wenzhong
dc.contributor.author Zhu, Yixi
dc.contributor.author Zhai, Hua
dc.date.accessioned 2022-11-18T09:32:00Z
dc.date.available 2022-11-18T09:32:00Z
dc.date.issued 2017-09-20
dc.identifier.citation Yu, Q., Han, W., Zhu, Y., & Zhai, H. (2017). Effect of puerarin on type II diabetes mellitus with orthopaedic footwear. Pakistan Journal of Pharmaceutical Sciences, 30. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/14079
dc.description.abstract In recent years, the antioxidant efficacy of puerarin has been recognized. However, there is less research on Puerarin used in diabetes. This paper analyzes the effect of puerarin on type II diabetes mellitus induced by streptozotocin combined with orthopaedic footwear. In this study, 80 Sprague Dawley (SD) rats were fed with high fat and high sucrose diet for one month, and 1% streptozotocin (STZ) was used to induce type II diabetes mellitus. After 6 weeks aerobic exercise and puerarin intervention in rats, the effect of aerobic exercise and puerarin intervention on antioxidant ability in diabetic rats was investigated. The results showed that aerobic exercise and puerarin intervention can improve the insulin resistance in rats. Meanwhile, the annual incidence of foot ulcers in diabetic patients is 2%, while orthopaedic footwear can reduce the probability of diabetic foot ulcers. In general, exercise and puerarin intervention can really play a role in the prevention and treatment of diabetes, such as improving the metabolic status of diabetic patients and reducing their dependence on drugs. en_US
dc.language.iso en en_US
dc.publisher Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi. en_US
dc.subject Puerarin en_US
dc.subject type II diabetes mellitus en_US
dc.subject insulin resistance en_US
dc.subject Streptozotocin STZ en_US
dc.title Effect of puerarin on type II diabetes mellitus with orthopaedic footwear en_US
dc.type Article en_US


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