PASTIC Dspace Repository

Serum levels of leptin, zinc and tryptophan with obesity: A case-control study

Show simple item record

dc.contributor.author Samad, Noreen
dc.date.accessioned 2022-11-23T05:07:56Z
dc.date.available 2022-11-23T05:07:56Z
dc.date.issued 2017-09-24
dc.identifier.citation Samad, N. (2017). Serum levels of leptin, zinc and tryptophan with obesity: A case-control study. Pakistan Journal of Pharmaceutical Sciences, 30(5). en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/14089
dc.description.abstract The obesity epidemic has turn into a major health threat worldwide and extensively responsible for the increased incidence of many diseases such as diabetes, cardiovascular disease and certain types of cancer. Excessive food intake along with the insufficient physical exercise is the basic impetus for this development. The aim of the present study is to evaluate the serum levels of leptin, zinc and tryptophan (TRP) in obese and non-obese subjects, which play major role in obesity. With the verbal and written consent eighty men were identified from the various areas of Karachi, Pakistan. The socio-demographic data including; age, body mass index (BMI), education and residence, of participants was collected. After providing informed consent, fasting blood samples were taken and serum was collected. The serum concentration of leptin, zinc and TRP were analyzed by ELISA (Enzyme-linked immunosorbent assay), FAAS (Flame atomic absorption spectrophotometer) and HPLC (High performance liquid chromatography) respectively. Results showed that levels of leptin were increased in obese than non-obese subjects significantly. On the other hand levels of zinc and TRP were significantly decreased in obese than non-obese subjects. Furthermore, there was a positive correlation found among leptin, zinc and TRP with obesity. Based on these facts the involvement of leptin, zinc and TRP with obesity will be discussed. en_US
dc.language.iso en en_US
dc.publisher Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi en_US
dc.subject obesity en_US
dc.subject leptin en_US
dc.subject zinc en_US
dc.subject TRP en_US
dc.subject ELISA en_US
dc.subject FAAS en_US
dc.subject HPLC en_US
dc.title Serum levels of leptin, zinc and tryptophan with obesity: A case-control study en_US
dc.type Article en_US


Files in this item

This item appears in the following Collection(s)

Show simple item record

Search DSpace


Advanced Search

Browse

My Account