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Bile acids and bile alcohols from Muraenesox bagio, Pomadasys argenteus and Lobeo rohita

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dc.contributor.author Rasheed, Munawwer
dc.contributor.author Ahmed, Mansoor
dc.contributor.author Hassan, Amir
dc.contributor.author Nazim, Urooj
dc.contributor.author Alam Khan, Rafeeq
dc.contributor.author Kamal, Mustafa
dc.contributor.author Abdur Rashid, Mohammad
dc.date.accessioned 2022-11-28T04:35:14Z
dc.date.available 2022-11-28T04:35:14Z
dc.date.issued 2017-10-02
dc.identifier.citation Rasheed, M., Ahmed, M., Hassan, A., Nazim, U., Khan, R. A., Kamal, M., & Rashid, M. A. (2017). Bile acids and bile alcohols from Muraenesox bagio, Pomadasys argenteus and Lobeo rohita. Pakistan Journal of Pharmaceutical Sciences, 30(5). en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/14099
dc.description.abstract Gallbladders bile of three well known commercial fish of South Asia region named Muraenesox bagio (locally called bam), Pomadasys argenteus (dother) and Lobeo rohita (rohu) were analysed on GC-MS, after derivatising the bile alcohols and bile acids as trimethylsilyl ether and trimethylsilyl-methyl ester, respectively. Cholic acid (1) and chenodeoxycholic acid (2) were found as major bile acids in all three species. Major bile alcohol in these fish was cholesterol (4), which was not detected in freshwater specie (L. rohita). M. bagio was also found to contain 3α,7α,12αtrihydroxy-23-cholesten-26-oic acid (3). Other bile acids and bile alcohols identified in L. rohita were allo deoxycholic acid (5), 12-oxo-3α-hydroxycholanic acid (6), 3α,7α,12α-trihydroxy-24-cholesten-26-oic acid (7), 5α- and 5βanhydrocyprinol (8 and 9, respectively) and 5β-homocholane-3α,7α,12α-25-tetrol (10). Besides acting as emulsifying agent in the digestion process, in non-mammalian vertebrates, e.g., fish, reptiles, etc. the analytical and elucidative studies on the bile contents disclose the diversity in metabolic pathways of cholesterol and indicate the existence of molecular evolution in the basic C27 skeleton of cholesterol. en_US
dc.language.iso en en_US
dc.subject GC-MS en_US
dc.subject marine and fresh water fish en_US
dc.title Bile acids and bile alcohols from Muraenesox bagio, Pomadasys argenteus and Lobeo rohita en_US
dc.type Article en_US


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